balanced crystalloid

PreclinicalSmall molecule

SSeoul National University Hospital

balanced crystalloid is one of 63 small molecule programs targeting Septic Shock. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Septic ShockActive, not recruiting

IntraoperativeCompleted

Septic ShockPreclinical

Active, not recruiting

IntraoperativePreclinical

Completed

Competition

Competitive Landscape

72 competitors in Septic Shock

#DrugCompanyPhaseTrials

Levophed

GGeneral Hospital of Ningxia Medical University

Approved

16 2

Giapreza

LLa Jolla Pharmaceutical Company

Approved

6 3

Merrem

BB. Braun Medical Inc.

Approved

3 4

Duragesic

CCephalon

Approved

2 5

Florinef

Jazz Pharmaceuticals

Phase 3

5 6

Osmitrol

BB. Braun Medical Inc.

Approved

—7

Integrilin

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Approved

—8

Methylthioninium Chloride

PProvepharm SAS

Phase 3

10 9

Brevibloc

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Phase 3

9 10

Albumin

LLaboratoire français de Fractionnement et de Biotechnologies

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2028

ApprovedRecruiting

Acute Kidney Injury

NCT07464431

Q3 2029

Phase 3Recruiting

Traumatic Brain Injury (TBI) Patients

NCT06953674

Clinical

Trials by Indication[1]

Acute Kidney Injury2 trials

Intraoperative Normal Saline Administration and Acute Kidney Injury in Patients Undergoing Liver Transplantation

Unknown status·SSeoul National University Hospital··NCT05386953·1,440 enrolled

Evaluating the Clinical Effectiveness of Sodium Bicarbonate for Critically Ill Patients With Metabolic Acidosis and Acute Kidney Injury (ESCALATE)

Recruiting·UUniversität Münster·Approved·NCT07464431·660 enrolled

Hemorrhagic Shock1 trial

Initial Resuscitation With Albumin in Hemorrhagic Shock to Reduce Positive Fluid Balance

Unknown status·SSeoul National University Hospital·N/A·NCT06111261·36 enrolled

Intraoperative1 trial

Metabolomics of Intraoperative Saline and Balanced Crystalloid Infusion

Completed·NNational Taiwan University Hospital·N/A·NCT04137042·56 enrolled

Colorectal Surgery1 trial

Perioperative Colloid vs Crystalloid in Patients Undergoing Colorectal Surgery

Terminated·UUniversity Hospital Muenster·Phase 4·NCT01303250·31 enrolled

Fluid Therapy1 trial

Fluid Therapy During Brain Tumor Resection in Children

Completed·FFederal University of São Paulo·Phase 2·NCT02707549·53 enrolled

4 more indications

Septic Shock1 trial

Balanced Crystalloid vs. Saline in Children With Septic Shock

Completed·—·N/A·NCT02835157·708 enrolled

Acute Pancreatitis1 trial

Balanced Crystalloid Solutions for Acute Pancreatitis

Unknown status·UUniversity Hospital Rijeka·Phase 4·NCT04688645·276 enrolled

Sepsis1 trial

Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital

Completed·UUniversity of Edinburgh·Phase 3·NCT04540094·300 enrolled

Traumatic Brain Injury (TBI) Patients1 trial

Saline vs. Balanced Crystalloid in Traumatic Brain Injury

Recruiting·UUniversity of Louisville·Phase 3·NCT06953674·600 enrolled

Sources

References

[1]
ClinicalTrials.gov — 10 trial records for balanced crystalloid. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — balanced crystalloid compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for balanced crystalloid. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Seoul National University Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: SSeoul National University Hospital

balanced crystalloid

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2028

Q3 2029

Trials by Indication[1]

Acute Kidney Injury2 trials

Hemorrhagic Shock1 trial

Intraoperative1 trial

Colorectal Surgery1 trial

Fluid Therapy1 trial

Septic Shock1 trial

Acute Pancreatitis1 trial

Sepsis1 trial

Traumatic Brain Injury (TBI) Patients1 trial

References

Drug Info

Quick Facts

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