Benzathine Penicillin

ApprovedSmall molecule

NNational Institute of Allergy and Infectious Diseases (NIAID)

Benzathine Penicillin is one of 86 small molecule programs targeting HIV infection. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

HIV InfectionActive, not recruiting

SyphilisActive, not recruiting

ArthritisActive, not recruiting

HIV InfectionApproved

Active, not recruiting

SyphilisPhase 3

Active, not recruiting

ArthritisApproved

Active, not recruiting

Competition

Competitive Landscape

326 competitors in HIV Infection

#DrugCompanyPhaseTrials

Leukine

Sanofi

Phase 3

2 2

Intron a

Merck & Co.

Phase 3

1 3

Sunlenca

Gilead

Phase 3

1 4

Buprenorphine/naloxone

Astellas

Phase 3

1 5

TWINRIX™

GSK

Phase 3

1 6

Benzathine Penicillin

NNational Institute of Allergy and Infectious Diseases (NIAID)

Approved

1 7

F/TAF

Gilead

Phase 3

1 8

F/TDF

Gilead

Phase 3

1 9

Interleukin 2

EEssen Biotech

Phase 3

1 10

Motexafin Gadolinium

PPharmacyclics LLC.

Phase 3

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Phase 3Recruiting

Clinical Trial

NCT04958122

Q3 2027

Post-ApprovalRecruiting

Arthritis

NCT06707194

Q3 2031

Post-ApprovalNot yet recruiting

Syphilis

NCT07457385

Clinical

Trials by Indication[1]

Syphilis3 trials

Azithromycin/Bicillin Syphilis

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 3·NCT00031499·593 enrolled

Serological Response to Retreatment of Serofast Early Syphilis Cases With Benzathine Penicillin

Unknown status·PPeking Union Medical College Hospital·Phase 4·NCT02884115·150 enrolled

Congenital Syphilis Treatment Trial (CONSISTENT) in Neonates

Not yet recruiting·UUniversity of Alabama at Birmingham·Phase 4·NCT07457385·374 enrolled

HIV infection1 trial

Phase 4 Comparative Trial of Benzathine Penicillin G for Treatment of Early Syphilis in Subjects With or Without HIV Infection

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 4·NCT03637660·249 enrolled

Arthritis1 trial

Effect and Safety of Benzathine Penicillin Combined With Etanercept on Spondyloarthritis

Recruiting·NNanfang Hospital, Southern Medical University·Phase 4·NCT06707194·340 enrolled

Clinical Trial1 trial

Cefixime Clinical Trial

Recruiting·UUniversity of Southern California·Phase 3·NCT04958122·400 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Benzathine Penicillin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Benzathine Penicillin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Benzathine Penicillin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Institute of Allergy and Infectious Diseases (NIAID) company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: NNational Institute of Allergy and Infectious Diseases (NIAID)

Benzathine Penicillin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Q3 2027

Q3 2031

Trials by Indication[1]

Syphilis3 trials

HIV infection1 trial

Arthritis1 trial

Clinical Trial1 trial

References

Drug Info

Quick Facts

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