cilastatine

Phase 2Small molecule

HHospital General Universitario Gregorio Marañon

cilastatine is one of 6 small molecule programs targeting Intraperitoneal Chemotherapy. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Intraperitoneal ChemotherapyRecruiting

Intraperitoneal ChemotherapyPhase 2

Recruiting

Competition

Competitive Landscape

6 competitors in Intraperitoneal Chemotherapy

#DrugCompanyPhaseTrials

Eloxatin

Teva

Phase 3

1 2

Camptosar

Pfizer

Phase 3

1 3

Platinol

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Phase 3

3 4

Sodium Thiosulfate

HHope Pharmaceuticals

Phase 2

1 5

Hyperthermic Intraperitoneal Chemotherapy

MMayo Clinic

Phase 2

1 6

cilastatine

HHospital General Universitario Gregorio Marañon

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2028

Phase 2Recruiting

Intraperitoneal Chemotherapy

NCT07229040

Clinical

Trials by Indication[1]

Intraperitoneal Chemotherapy1 trial

A Double-blind Non Inferiority Clinical Trial to Compare the Nephroprotection of Cilastatn Versus Thiosulfate in Patients Undergoing Debulking Surgery With Intraoperative Hyperthermic Intraperitoneal Chemotherapy With Cisplatin.

Recruiting·HHospital General Universitario Gregorio Marañon·Phase 2·NCT07229040·90 enrolled

Sources

References

[1]
ClinicalTrials.gov — 1 trial record for cilastatine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — cilastatine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for cilastatine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Hospital General Universitario Gregorio Marañon company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: HHospital General Universitario Gregorio Marañon

cilastatine

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2028

Trials by Indication[1]

Intraperitoneal Chemotherapy1 trial

References

Drug Info

Quick Facts

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