Coenzyme Q10

ApprovedSmall molecule

MMclean Hospital

Coenzyme Q10 is one of 528 small molecule programs targeting Charcot-Marie-Tooth disease. It is currently in Approved.

Indications

Total Trials

Active Trials

527

Competitors

Pipeline

Status by Indication[3][1]

Indication

Charcot-Marie-Tooth DiseaseActive, not recruiting

Systemic Lupus ErythematosusActive, not recruiting

Cardiac ArrestActive, not recruiting

Aphthous UlcerActive, not recruiting

HepatitisActive, not recruiting

Peripheral NeuropathyActive, not recruiting

MyopathyActive, not recruiting

Progressive Supranuclear PalsyActive, not recruiting

EncephalopathyActive, not recruiting

Congestive Heart FailureActive, not recruiting

Charcot-Marie-Tooth DiseasePhase 1/Phase 2

Active, not recruiting

Systemic Lupus ErythematosusPhase 2

Active, not recruiting

Cardiac ArrestPhase 2

Active, not recruiting

Aphthous UlcerPreclinical

Active, not recruiting

HepatitisPhase 3

Active, not recruiting

Peripheral NeuropathyPhase 1

Active, not recruiting

MyopathyPreclinical

Active, not recruiting

Progressive Supranuclear PalsyPhase 2

Active, not recruiting

EncephalopathyPreclinical

Active, not recruiting

Congestive Heart FailurePreclinical

Active, not recruiting

Showing 10 of 19 indications

Competition

Competitive Landscape

2829 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Coenzyme Q10

MMclean Hospital

Approved

2 2

DATROWAY

Daiichi Sankyo

Preclinical

4 3

Megace

Bristol-Myers Squibb

Preclinical

4 4

Zolymbus

AbbVie

Preclinical

1 5

Methylthioninium Chloride

PProvepharm SAS

Preclinical

3 6

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 7

Effexor

WWyeth-Lederle Vaccines

Preclinical

2 8

Recentin

NNational Cancer Institute (NCI)

Preclinical

2 9

Chirocaine

PPurdue Pharma LP

Preclinical

1 10

Acupan

YYonsei University

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Bipolar Depression2 trials

CoQ10 in Geriatric Bipolar Depression

Completed·MMclean Hospital·N/A·NCT00720369·42 enrolled

Exploring the Effects of Coenzyme Q10 on Bioenergetics Metabolism in Geriatric Bipolar Depression

Completed·MMclean Hospital·N/A·NCT01390389·19 enrolled

Breast Cancer2 trials

Immediate or Delayed Naturopathic Medicine in Combination With Neo-Adjuvant Chemotherapy for Breast Cancer

Terminated·MMidwestern Regional Medical Center·Phase 1/2·NCT02486796·5 enrolled

Coenzyme Q10 and Chemotherapeutic Toxicity in Breast Cancer Patients

Completed·—·Phase 2·NCT06570811·40 enrolled

Encephalopathy1 trial

Coenzyme Q10 and Meclofenoxate in Hepatic Encephalopathy

Unknown status·ZZagazig University·N/A·NCT03961087·300 enrolled

Outcome1 trial

Coenzyme q 10 and Fertility Outcome in Women With Clomiphene Resistant PCOS

Completed·—·Phase 4·NCT04302532·149 enrolled

Polycystic Ovary Syndrome1 trial

Coenzyme Q10 and Clomiphene Citrate (CC) for Ovulation Induction in Polycystic Ovary Syndrome

Completed·MMansoura University·N/A·NCT01910766·110 enrolled

25 more indications

Clinical Trial1 trial

Clinical Trial of High Dose CoQ10 in ALS

Completed·—·Phase 2·NCT00243932·185 enrolled

Charcot-Marie-Tooth disease1 trial

Effects of Coenzyme Q10 on Charcot-Marie-Tooth Disease

Completed·—·Phase 1/2·NCT00541164·23 enrolled

COVID-191 trial

Coenzyme Q10 as Treatment for Long Term COVID-19

Completed·—·Phase 2·NCT04960215·121 enrolled

Inflammatory Response1 trial

Protective Effect of CoQ10 Against Negative Inflammatory Response and Organ Dysfunction in Cardiovascular Surgery (PANDA V)

Recruiting·NNanjing Medical University·N/A·NCT04444349·500 enrolled

Terminated·MMassachusetts General Hospital·Phase 3·NCT00608881·609 enrolled

Dilated Cardiomyopathy1 trial

Coenzyme Q10 Supplementation in Children With Idiopathic Dilated Cardiomyopathy

Completed·—·Phase 4·NCT02115581·38 enrolled

Congestive Heart Failure1 trial

Atorvastatin/CoenzymeQ10 in Congestive Heart Failure

Unknown status·IIsfahan University of Medical Sciences·N/A·NCT01925937·30 enrolled

Parkinson's Disease1 trial

Parkinson's Disease Treatment With Coenzyme Q10

Completed·NNational Institute of Neurological Disorders and Stroke (NINDS)·Phase 2·NCT00004731

Thoracoscopic Surgery1 trial

The Effect of Coenzyme Q10 in Preventing Pain After Thoracoscopic Surgery

Recruiting·TThe Second Affiliated Hospital of Chongqing Medical University·Phase 4·NCT06743802·264 enrolled

Ovarian Function1 trial

The Effect of Jiajian Guishen Granules on the Modulation of Ovarian Function in Patients With Poor Ovarian Response(POR)

Not yet recruiting·SShi Yun·Phase 1·NCT06089395·76 enrolled

Myopathy1 trial

CoEnzyme Q10 in Statin Myopathy

Unknown status·HHartford Hospital·N/A·NCT01140308·135 enrolled

Infertility1 trial

Neotililty Trial: Effect of Coenzyme Q10 on Semen Parameters in Men With Idiopathic Infertility

Withdrawn·PPharmEvo Pvt Ltd·Phase 4·NCT03104998

Progressive Supranuclear Palsy1 trial

Study About Safety and Efficacy of Coenzyme Q10 in Progressive Supranuclear Palsy

Completed·GGerman Parkinson Study Group (GPS)·Phase 2·NCT00328874·20 enrolled

Cardiac Arrest1 trial

Coenzyme Q10 in Post-Cardiac Arrest Cerebral Resuscitation

Completed·—·Phase 2·NCT01319110·10 enrolled

Systemic Lupus Erythematosus1 trial

The Effect of Co-enzyme Q10 on the Clinical Outcome of Pediatric Patients With Systemic Lupus Erythematosus

Completed·—·Phase 2·NCT07096557·60 enrolled

Peripheral Neuropathy1 trial

The Role of Coenzyme Q10 in the Prophylaxis of Oxaliplatin Induced Peripheral Neuropathy in Patients With Colorectal Cancer

Recruiting·Ttoqa saad mohammed mohammed·Phase 1·NCT06856447·22 enrolled

Ataxia1 trial

Coenzyme Q10 in Adult-Onset Ataxia

Completed·TThe University of Texas Medical Branch, Galveston·Phase 1·NCT00957216·1 enrolled

Coenzyme Q101 trial

Coenzyme Q10 and Dentoalveolar Cyst

Active, not recruiting·FFayoum University·Phase 2·NCT05873673·20 enrolled

Hepatitis1 trial

Comparative Clinical Study to Evaluate the Efficacy and Safety of Rosuvastatin Vs CoQ10 on Nonalcoholic Steatohepatitis

Unknown status·TTanta University·Phase 3·NCT05731596·46 enrolled

Dialysis Patients1 trial

The Effect of CoQ10 Administration on Hemodialysis Patients

Completed·UUniversity of Shizuoka·Phase 4·NCT00307996·40 enrolled

Aphthous Ulcer1 trial

Clinical Evaluation of Topical Coenzyme Q10 in Management of Oral Aphthous Ulcer

Unknown status·—·N/A·NCT03213769·52 enrolled

Tooth Extraction1 trial

Evaluation the Effect of Coenzyme Q10 on Tissue Healing Process in Patients Undergoing Wisdom Tooth Extraction

Not yet recruiting·ZZahra Nejati·Phase 4·NCT06452134·70 enrolled

Mitochondria1 trial

Vestibular Function Using Mitochondrial Antioxidant Therapy

Withdrawn·TThe University of Texas Health Science Center at San Antonio·Phase 1·NCT05945160

Sources

References

[1]
ClinicalTrials.gov — 32 trial records for Coenzyme Q10. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Coenzyme Q10 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Coenzyme Q10. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Mclean Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: MMclean Hospital

Coenzyme Q10

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Bipolar Depression2 trials

Breast Cancer2 trials

Encephalopathy1 trial

Outcome1 trial

Polycystic Ovary Syndrome1 trial

Clinical Trial1 trial

Charcot-Marie-Tooth disease1 trial

COVID-191 trial

Inflammatory Response1 trial

Duchenne Muscular Dystrophy1 trial

Bipolar Disorder1 trial

Huntington's Disease (HD)1 trial

Dilated Cardiomyopathy1 trial

Congestive Heart Failure1 trial

Parkinson's Disease1 trial

Thoracoscopic Surgery1 trial

Ovarian Function1 trial

Myopathy1 trial

Infertility1 trial

Progressive Supranuclear Palsy1 trial

Cardiac Arrest1 trial

Systemic Lupus Erythematosus1 trial

Peripheral Neuropathy1 trial

Ataxia1 trial

Coenzyme Q101 trial

Hepatitis1 trial

Dialysis Patients1 trial

Aphthous Ulcer1 trial

Tooth Extraction1 trial

Mitochondria1 trial

References

Drug Info

Quick Facts

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