Depakote

ApprovedSmall molecule

Teva

Depakote is one of 152 small molecule programs targeting Epilepsy. It is currently in Approved.

Indications

Total Trials

Active Trials

151

Competitors

Pipeline

Status by Indication[3][1]

Indication

EpilepsyActive, not recruiting

SchizophreniaActive, not recruiting

Bipolar DisorderActive, not recruiting

DementiaActive, not recruiting

EpilepsyPhase 1

Active, not recruiting

SchizophreniaPreclinical

Active, not recruiting

Bipolar DisorderApproved

Active, not recruiting

DementiaPhase 1

Active, not recruiting

Competition

Competitive Landscape

583 competitors in Schizophrenia

#DrugCompanyPhaseTrials

Depakote

Teva

Approved

1 2

Celexa

AbbVie

Preclinical

4 3

Inapsine

Alnylam Pharmaceuticals

Preclinical

1 4

Zocor

OOrganon and Co

Preclinical

6 5

Depakote

AbbVie

Preclinical

—6

Comtan

Orion Corporation, Orion Pharma

Preclinical

1 7

Permax

VValeant Pharmaceuticals

Preclinical

1 8

Catapres

Boehringer Ingelheim

Preclinical

1 9

Inversine

TTargacept Inc.

Preclinical

1 10

Vivarin

HHikma Pharmaceuticals LLC

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Fasting Conditions4 trials

Divalproex Sodium 500 mg Extended Release Tablets Under Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT00974441·48 enrolled

Divalproex Sodium Delayed-Release Tablets Under Non-Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT00834990·24 enrolled

Divalproex Sodium Delayed-Release Tablets Under Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT00834639·24 enrolled

Show 1 more trial

Divalproex Sodium 500 mg Extended Release Tablets Under Non-Fasting Conditions

Completed· Teva logo

Teva·Phase 1·NCT00974012·24 enrolled

Bipolar Disorder3 trials

Safety Study of Depakote Versus Lithium in African Americans With Bipolar Disorder

Withdrawn·LLawson, William B., M.D., PhD, DFAPA·Phase 4·NCT01075126·50 enrolled

Abilify in Bipolar Disorder for 24 Weeks Treatment Effectiveness

Completed·KKorea Otsuka Pharmaceutical Co., Ltd.·Phase 4·NCT00545675·146 enrolled

Abilify in Bipolar Disorder for 6 Weeks Treatment Effectiveness

Completed·KKorea Otsuka Pharmaceutical Co., Ltd.·Phase 4·NCT00545142·280 enrolled

Solid Tumor Malignancies1 trial

Treatment With ATRA-IV and Depakote in Patients With Advanced Solid Tumor Malignancies

Terminated·WWeill Medical College of Cornell University·Phase 1·NCT00195156

Dementia1 trial

Study of Depakote for Behavioral and Psychological Symptoms in Dementia

Unknown status·HHearthstone Alzheimer Care·Phase 1·NCT00197834·20 enrolled

Schizophrenia1 trial

Effects of Atypical Antipsychotic and Valproate Combination Therapy on Glucose and Lipid Metabolism in Schizophrenia

Completed·WWashington University School of Medicine·N/A·NCT00552500·120 enrolled

3 more indications

Fed1 trial

Fed Bioequivalence Study of Divalproex Sodium Delayed-Release Tablets, 500 mg

Completed· Mylan Pharmaceuticals Inc logo

Mylan Pharmaceuticals Inc·Phase 1·NCT01183676·20 enrolled

Epilepsy1 trial

A Study in Stable Epilepsy Patients Comparing Brand and Generic Divalproex Sodium Extended Release Tablets

Unknown status·VVince & Associates Clinical Research, Inc.·Phase 1·NCT01898676·16 enrolled

Unspecified1 trial

Bioequivalence Study of Divalproex Sodium Delayed-Release Tablets, 500 mg

Completed· Mylan Pharmaceuticals Inc logo

Mylan Pharmaceuticals Inc·Phase 1·NCT01184391·17 enrolled

Sources

References

[1]
ClinicalTrials.gov — 13 trial records for Depakote. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Depakote compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Depakote. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Teva company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Teva

Depakote

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Fasting Conditions4 trials

Bipolar Disorder3 trials

Solid Tumor Malignancies1 trial

Dementia1 trial

Schizophrenia1 trial

Fed1 trial

Epilepsy1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

Related News