Heparin sodium

ApprovedSmall molecule

Heparin sodium is one of 208 small molecule programs targeting Severe Acute Respiratory Syndrome. It is currently in Approved.

Indications

Total Trials

Active Trials

207

Competitors

Pipeline

Status by Indication[3][1]

Indication

Severe Acute Respiratory SyndromeActive, not recruiting

AneurysmActive, not recruiting

SepsisActive, not recruiting

Venous MalformationActive, not recruiting

Acute Kidney InjuryActive, not recruiting

COVID-19Active, not recruiting

Lung TransplantationActive, not recruiting

Severe Acute Respiratory SyndromeApproved

Active, not recruiting

AneurysmPreclinical

Active, not recruiting

SepsisPhase 3

Active, not recruiting

Venous MalformationPreclinical

Active, not recruiting

Acute Kidney InjuryApproved

Active, not recruiting

COVID-19Phase 1/Phase 2

Active, not recruiting

Lung TransplantationApproved

Active, not recruiting

Competition

Competitive Landscape

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

Heparin sodium

Haisco Pharmaceutical Group Co., Ltd.

Approved

1 2

Activella

Eli Lilly

Preclinical

—3

Proventil

Mylan Pharmaceuticals Inc

Preclinical

1 4

Precedex

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Preclinical

1 5

Aprotinin

Bayer

Preclinical

1 6

Antithrombin-III

Octapharma

Preclinical

1 7

Interferon-Gamma

SSPP Pharmaclon Ltd.

Preclinical

1 8

Antihypertensive Agents

NNational Heart, Lung, and Blood Institute (NHLBI)

Preclinical

1 9

Conventional

PPopulation Health Research Institute

Preclinical

1 10

Moderna COVID-19 Vaccine

Moderna

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Tics2 trials

Evaluation of the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamic Effects of PER977 Following Heparin

Completed·AAMAG Pharmaceuticals, Inc.·Phase 1/2·NCT02206087·60 enrolled

A Study of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Ascending Dosed of HSK36273 in Healthy Volunteers

Completed· Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.·Phase 1·NCT05742126·54 enrolled

Severe Acute Respiratory Syndrome1 trial

Nebulized Heparin in Severe Acute Respiratory Syndrome COVID-19

Unknown status·CClinica San Camilo, Argentina·Phase 4·NCT04530578·200 enrolled

Acute Kidney Injury1 trial

Oxidative Stress and Circulating Nuclear DNA (cfDNA) in Acute Kidney Injury and Continuous Renal Replacement Therapies.

Terminated·FFernando Sanchez·Phase 4·NCT06646328·20 enrolled

Chronic Renal Failure1 trial

Study of Clinical Non-inferiority of Actparin® (Laboratorio Bergamo) Compared to Heparin Sodium (APP Pharmaceuticals), in Patients With Chronic Renal Failure

Unknown status·LLaboratório Químico Farmacêutico Bergamo Ltda.·Phase 3·NCT01346215·132 enrolled

COVID-191 trial

Enriched Heparin Anti COVID-19 Trial

Completed·UUPECLIN HC FM Botucatu Unesp·Phase 1/2·NCT04743011·27 enrolled

11 more indications

Aneurysm1 trial

Effect of Different Heparinization Schemes on Prognosis of Intracranial Aneurysm

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·N/A·NCT05749393·90 enrolled

Sepsis1 trial

Efficacy and Safety of Unfractionated Heparin on Severe Sepsis With Suspected Disseminated Intravascular Coagulation

Unknown status·—·Phase 3·NCT02654561·600 enrolled

Lung Transplantation1 trial

Heparin-free Extracorporeal Membrane Oxygenation Support During Clinical Lung Transplantation

Unknown status·MMedical University of Vienna·Phase 4·NCT05697692·80 enrolled

Venous malformation1 trial

Exploration of Anticoagulation Program in Cerebral Aneurysm and Arteriovenous Malformations With Hybrid Operation 2

Unknown status·—·N/A·NCT03306836·408 enrolled

ECMO1 trial

Bivalirudin vs Heparin in ECMO Patients

Withdrawn·JJohns Hopkins University·Phase 1·NCT03707418

Hemodialysis1 trial

Taurolock Hep 500 Versus Unfractionated Heparin as Anti-inflammatory in Hemodialysis Catheters.

Unknown status·—·Phase 4·NCT03539718·60 enrolled

Renal Replacement Therapy1 trial

A Clinical Study to Evaluate the Efficacy, Safety and PK/PD Profiles of Anticoagulation of HSK36273 for Injection in Continuous Renal Replacement Therapy Subjects

Unknown status· Haisco Pharmaceutical Group Co., Ltd. logo

Haisco Pharmaceutical Group Co., Ltd.·Phase 2·NCT05602129·156 enrolled

STEMI1 trial

Early Administration of Heparin At FMC for PPCI of STEMI Patients

Completed·RRenmin Hospital of Wuhan University·N/A·NCT05329155·1,145 enrolled

Safety and Efficacy1 trial

Safety and Efficacy of Low-dose hEparinization in Cerebral Angiography sTudy

Completed·XXuanwu Hospital, Beijing·Phase 4·NCT06365398·180 enrolled

Thrombosis1 trial

Continuous Heparin Infusion to Prevent Catheter-related Thrombosis

Completed·GGuangdong Provincial People's Hospital·N/A·NCT04767113·35 enrolled

Unspecified1 trial

The Effect of Heparinization Due to LBW

Unknown status·—·Phase 4·NCT03113708·50 enrolled

Sources

References

[1]
ClinicalTrials.gov — 17 trial records for Heparin sodium. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Heparin sodium compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Heparin sodium. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Haisco Pharmaceutical Group Co., Ltd. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Haisco Pharmaceutical Group Co., Ltd.

Heparin sodium

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Tics2 trials

Severe Acute Respiratory Syndrome1 trial

Acute Kidney Injury1 trial

Chronic Renal Failure1 trial

COVID-191 trial

Aneurysm1 trial

Sepsis1 trial

Lung Transplantation1 trial

Venous malformation1 trial

ECMO1 trial

Hemodialysis1 trial

Renal Replacement Therapy1 trial

STEMI1 trial

Safety and Efficacy1 trial

Thrombosis1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

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