Lipitor

(atorvastatin)

ApprovedSmall molecule

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Atorvastatin is used to lower cholesterol and reduce the risk of heart disease and stroke by helping your body remove excess cholesterol from the blood.[2] Lipitor is currently approved and in use across 192 indications[4].[1]

Lipitor is one of 3030 small molecule programs targeting Insulin resistance. It is currently in Approved.

192

Indications

645

Total Trials

Active Trials

3,029

Competitors

FDA Applications

NDA/BLA/ANDA regulatory filings

Patents

Pipeline

Status by Indication[4][1]

Indication

Insulin ResistanceActive, not recruiting

Percutaneous Transluminal Coronary AngioplastyApproved

Childhood CancerActive, not recruiting

Coronary Artery DiseaseApproved

CalcificationActive, not recruiting

Metabolic SyndromeApproved

HIV InfectionApproved

Systemic Lupus ErythematosusActive, not recruiting

Cirrhosis of LiverApproved

Disorder of Lipid MetabolismApproved

Insulin ResistanceApproved

Active, not recruiting

Percutaneous Transluminal Coronary AngioplastyApproved

Approved

Childhood CancerPhase 2

Active, not recruiting

Coronary Artery DiseaseApproved

Approved

CalcificationApproved

Active, not recruiting

Metabolic SyndromeApproved

Approved

HIV InfectionApproved

Approved

Systemic Lupus ErythematosusPhase 2

Active, not recruiting

Cirrhosis of LiverApproved

Approved

Disorder of Lipid MetabolismApproved

Approved

Showing 10 of 189 indications

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Lipitor

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

9 2

Trodelvy

Gilead

Preclinical

37 3

Nolvadex

SSan Diego Pacific Oncology & Hematology Associates

Preclinical

78 4

Prolia

Amgen

Preclinical

14 5

Voltaren

Novartis

Preclinical

1 6

Systemic Therapy

Bristol-Myers Squibb

Preclinical

1 7

QS21

MMemorial Sloan Kettering Cancer Center

Preclinical

3 8

Perflutren Lipid Microsphere

IImaRx Therapeutics

Preclinical

1 9

Bisphosphonate

Amgen

Preclinical

2 10

Ablavar

LLantheus Medical Imaging

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Post-ApprovalRecruiting

Cardiovascular

NCT06632379

Q1 2027

Post-ApprovalActive, not recruiting

Hepatocellular Carcinoma

NCT03024684

Phase 1Recruiting

Cardiovascular

NCT06961630

Q3 2027

Recruiting

Cardiovascular Disease

NCT06858332

Q4 2027

Phase 3Recruiting

Exercise

NCT05796973

Clinical

Trials by Indication[1]

Atorvastatin39 trials

Study to Evaluate the Pharmacokinetic Interaction Between Fimasartan and Atorvastatin in Healthy Male Volunteers

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT02397590·36 enrolled

A Pre-Op Window Study Evaluating Anti-Proliferative Effects of Atorvastatin on the Endometrium

Completed·UUNC Lineberger Comprehensive Cancer Center·Phase 1·NCT02767362·24 enrolled

Ezetimibe Plus (+) Simvastatin Versus Atorvastatin Comparative Study (0653A-092)(COMPLETED)

Completed·OOrganon and Co·Phase 4·NCT00166504·203 enrolled

Show 36 more trials

Atorvastatin for Preventing Occlusion and Restenosis After Intracranial Artery Stenting

Completed·JJinling Hospital, China·Phase 4·NCT01255852·100 enrolled

Drug-Drug Interaction Study Between Colchicine and Atorvastatin

Completed·MMutual Pharmaceutical Company, Inc.·Phase 1·NCT00960323·24 enrolled

A Phase 1 Study to Evaluate the Effects of Fluconazole and Atorvastatin on the Pharmacokinetics of TAK-385 in Healthy Subjects

Completed· Takeda logo

Takeda·Phase 1·NCT02093390·40 enrolled

Effects of Atorvastatin on Human Semen and Gonadal Hormones

Completed·UUniversity Hospital, Clermont-Ferrand·Phase 1·NCT02094313·17 enrolled

Single Dose of Atorvastatin and Circulating Endothelial Microparticles

Unknown status·SSun Yat-sen University·Phase 4·NCT02023892·30 enrolled

A Study to Compare the Pharmacokinetics of Fimasartan/Atorvastatin Combination Tablet

Completed· Boryung Pharmaceutical Co., Ltd logo

Boryung Pharmaceutical Co., Ltd·Phase 1·NCT02566187·99 enrolled

STUDY TO EVALUATE THE EFFECT OF PF-06882961 ON SINGLE DOSE ATORVASTATIN, MEDAZOLAM AND ORALCONTRACEPTIVE PHARMACOKINETICS IN HEALTHY ADULT PARTICIPANTS

Completed· Pfizer logo

Pfizer·Phase 1·NCT05093205·35 enrolled

ECC5004 DDI Study With Atorvastatin, Rosuvastatin, Digoxin and Midazolam in Healthy Participants

Completed·EEccogene·Phase 1·NCT06293742·48 enrolled

A Formulation Screening Study of Dalcetrapib and Atorvastatin in Healthy Volunteers

Completed· Roche logo

Roche·Phase 1·NCT01363999·24 enrolled

Carotid B-Mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrpib/Atorvastatin to Atorvastatin Alone.

Completed· Pfizer logo

Pfizer·Phase 3·NCT00136981·800 enrolled

Effect of Atorvastatin on Glycemic Control in Prediabetic Patients

Completed·—··NCT02470455·75 enrolled

Comparison of Vascular Effects After Therapy With Irbesartan and Atorvastatin.

Completed·TTechnische Universität Dresden·N/A·NCT00154024

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

Completed· AstraZeneca logo

AstraZeneca·Phase 1·NCT00722956·12 enrolled

Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney

Completed·IInstituto Mexicano del Seguro Social·Phase 3·NCT02355704·48 enrolled

STELLAR-Rosuvastatin vs. Atorvastatin, Pravastatin, Simvastatin Across Dose Ranges

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654537·5,625 enrolled

Study of Influence of Atorvastatin on the Repolarisation Phase of Cardiomyocytes

Unknown status·MMasaryk University·N/A·NCT00520585

A Drug-Drug Interaction (DDI) Study of HDM1002 With Repaglinide, Atorvastatin, Digoxin and Rosuvastatin in Healthy Subjects and Overweight Subjects.

Not yet recruiting·HHangzhou Zhongmei Huadong Pharmaceutical Co., Ltd.·Phase 1·NCT06601517·30 enrolled

Optimalization of Nephroprotection Using Atorvastatin (Sortis)

Completed·MMedical University of Gdansk·N/A·NCT00572312

Clinical Assessment Of Association Pharmacokinetics Atorvastatin + Losartana + Hydrochlorothiazide

Completed·AAzidus Brasil·Phase 1·NCT01692717·90 enrolled

Study to Determine if Atorvastatin Reduces Size and Stiffness of Muscle in the Left Ventricle of the Heart

Completed·UUniversity of Calgary·Phase 3·NCT00317967·22 enrolled

Atorvastatin in Perioperative Vascular Surgery - Pilot Study

Completed·UUniversity of Campinas, Brazil·Phase 4·NCT00610545·100 enrolled

A 16 Week Comparative Study of Fenofibrate Versus Ezetimibe as Add-on Therapy to Atorvastatin

Completed·AAbbott·Phase 3·NCT00195793·174 enrolled

Randomized Placebo-Controlled Trial of Atorvastatin in HIV-Positive Patients Not on Antiretroviral Therapy

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00367458·24 enrolled

Evaluate the Effect of Atorvastatin on the Pharmacokinetics of Lomitapide in Healthy Subjects.

Completed·AAegerion Pharmaceuticals, Inc.·Phase 1·NCT02080455·32 enrolled

Effect of Gemcabene on the Pharmacokinetics of Atorvastatin in Healthy Volunteers

Completed·NNeuroBo Pharmaceuticals Inc.·Phase 1·NCT02587416·20 enrolled

Investigating the Influence of Semaglutide on the Pharmacokinetics of Single Doses of Atorvastatin and Digoxin in Healthy Subjects

Completed· Novo Nordisk logo

Novo Nordisk·Phase 1·NCT02243098·31 enrolled

Ezetimibe (EZ)/Atorvastatin (Ator) (MK-0653C) vs. Ator in Chinese Hypercholesterolemic Participants (MK-0653C-439)

Completed·OOrganon and Co·Phase 3·NCT03768427·454 enrolled

Polaris - Crestor 40 mg vs Atorvastatin 80 mg for 26 Weeks

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653588

Atorvastatin Study For The Treatment Of High Cholesterol In Patients From Thailand

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00647543·242 enrolled

Crossover Evaluation of Effect of Atorvastatin on PK of Irinotecan in CRC Patients Receiving FOLFIRI

Withdrawn·UUNC Lineberger Comprehensive Cancer Center·Phase 1·NCT01605344

A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides

Completed· Pfizer logo

Pfizer·Phase 3·NCT00134498·160 enrolled

Drug-Drug Interaction Study of Vadadustat With Rosuvastatin, Sulfasalazine, Pravastatin, Atorvastatin and Simvastatin

Completed·AAkebia Therapeutics·Phase 1·NCT03801733·134 enrolled

Carotid B-mode Ultrasound Study to Compare Anti-Atherosclerotic Effect of Torcetrapib/Atorvastatin to Atorvastatin.

Terminated· Pfizer logo

Pfizer·Phase 3·NCT00134238·755 enrolled

Effect of Short Term Atorvastatin Treatment,80mg/Day on Early Regression of Carotid Artery Atherosclerotic Lesions

Unknown status·—·Phase 4·NCT00640744·12 enrolled

Clopidogrel and Atorvastatin Treatment During Carotid Artery Stenting

Unknown status·—·Phase 4·NCT01572623·150 enrolled

A Study Evaluating Bioequivalence of a Fixed Dose Combination Versus Individual Tablets of Bempedoic Acid, Ezetimibe, and Atorvastatin

Completed· Daiichi Sankyo logo

Daiichi Sankyo·Phase 1·NCT07235189·58 enrolled

Hypercholesterolemia11 trials

A Study of Evacetrapib (LY2484595) in Combination With Atorvastatin in Japanese Participants With Primary Hypercholesterolemia

Terminated· Eli Lilly logo

Eli Lilly·Phase 3·NCT02260648·149 enrolled

Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy

Completed· Sanofi logo

Sanofi·Phase 2·NCT01288443·183 enrolled

Evaluation of Ezetimibe and Atorvastatin Coadministration Versus Atorvastatin or Rosuvastatin Monotherapy in Japanese Patients With Hypercholesterolemia (Study P06027)(COMPLETED)

Completed·OOrganon and Co·Phase 4·NCT00871351·125 enrolled

Show 8 more trials

Usability Study of the Commercial Auto-injector Device and the New Auto-injector Device (SYDNEY) in Patients With High or Very High CV Risk With Hypercholesterolemia Not Adequately Controlled With Their Lipid-Modifying Therapy

Completed· Sanofi logo

Sanofi·Phase 3·NCT03415178·69 enrolled

Statins in Children With Type 1 Diabetes and Hypercholesterolemia

Completed·NNemours Children's Clinic·Phase 3·NCT01236365·42 enrolled

Efficacy And Safety Study Of Atorvastatin Versus Simvastatin In Type 2 Diabetic Subjects With Hypercholesterolemia

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00141141·383 enrolled

Mercury II - Compare the Efficacy and Safety of Lipid Lowering Agents Atorvastatin and Simvastatin With Rosuvastatin in High Risk Subjects With Type IIa and IIb Hypercholesterolemia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654407·4,875 enrolled

Efficacy and Safety of Alirocumab in Patients With Hypercholesterolemia Not Adequately Controlled With Non-statin Lipid Modifying Therapy or the Lowest Strength of Statin

Completed· Sanofi logo

Sanofi·Phase 3·NCT02584504·163 enrolled

A Clinical Trial Study to Evaluate Efficacy and Safety of Atorvastatin in Korean Patients With Hypercholesterolemia

Completed·YYonsei University·Phase 4·NCT01081548·17 enrolled

Efficacy and Safety Evaluation of Alirocumab (SAR236553/REGN727) in Patients With Primary Hypercholesterolemia on Stable Atorvastatin Therapy in Japan

Completed· Sanofi logo

Sanofi·Phase 2·NCT01812707·100 enrolled

Ezetimibe Plus Atorvastatin Versus Atorvastatin in Untreated Subjects With Primary Hypercholesterolemia and Coronary Heart Disease (P03396)

Completed·OOrganon and Co·Phase 3·NCT00650689·122 enrolled

Atherosclerosis6 trials

The Effects of Atorvastatin in Patients With Atherosclerosis

Completed·—·Phase 3·NCT00115817·36 enrolled

Lupus Atherosclerosis Prevention Study

Completed·JJohns Hopkins University·Phase 4·NCT00120887·200 enrolled

Evaluation of Atorvastatin on Atherosclerosis Composition

Completed·EEmory University·N/A·NCT00576576·27 enrolled

Show 3 more trials

Statin Therapy to Improve Atherosclerosis in HIV Patients

Completed·MMassachusetts General Hospital·N/A·NCT00965185·40 enrolled

Systemic Immunomodulatory Effects and Pharmacogenetics of Atorvastatin in Early Atherosclerosis

Completed·UUniversity of Florida·Phase 4·NCT00361283·108 enrolled

Effect of Atorvastatin and Lifestyle Intervention on Progression of Pre-Clinical Atherosclerosis

Unknown status·MMinistry of Science and Technology of the People´s Republic of China·N/A·NCT00723320·1,200 enrolled

Acute Coronary Syndrome5 trials

Comparison of Rosuvastatin and Atorvastatin in Patients With Acute Coronary Syndrome

Completed·QQueen's University·Phase 4·NCT00665834·18 enrolled

Atorvastatin Pre-Treatment Study In Asian Patients With Acute Coronary Syndrome

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00728988·499 enrolled

Intensive Lipid Lowering Treatment in Non-ST-elevation Acute Coronary Syndrome (NSTE-ACS) Patients

Unknown status·SShanghai Jiao Tong University School of Medicine·Phase 4·NCT01040936·300 enrolled

Show 2 more trials

Intensive Statin Therapy in PCI Patient With Acute Coronary Syndrome

Unknown status·XXijing Hospital·Phase 4·NCT01372839·300 enrolled

China Intensive Lipid Lowering With Statins in Acute Coronary Syndrome

Unknown status·MMinistry of Science and Technology of the People´s Republic of China·N/A·NCT00728013·1,600 enrolled

Safety and Efficacy5 trials

Safety and Efficacy of Lapaquistat Acetate Taken Alone and With Atorvastatin in Subjects With Primary Dyslipidemia

Completed· Takeda logo

Takeda·Phase 3·NCT00487994·2,130 enrolled

Safety and Efficacy of Atorvastatin v. Placebo on HCC Risk

Recruiting·RRaymond Chung·Phase 2·NCT05028829·60 enrolled

Safety and Efficacy Study Comparing ABT-335 Coadministered With Atorvastatin and Ezetimibe to Atorvastatin Coadministered With Ezetimibe in Subjects With Multiple Abnormal Lipid (Fat) Levels in the Blood

Completed·AAbbott·Phase 3·NCT00639158·543 enrolled

Show 2 more trials

Study To Evaluate The Safety And Efficacy Of Torcetrapib/Atorvastatin In Subjects With Familial Hypercholerolemia

Completed· Pfizer logo

Pfizer·Phase 3·NCT00134485·400 enrolled

Evaluate Safety and Efficacy of ABT-335 in Combination With Atorvastatin in Subjects With Multiple Abnormal Lipid Levels in the Blood

Completed·AAbbott·Phase 3·NCT00300469·613 enrolled

102 more indications

Coronary Artery Disease5 trials

Comparison of Pitavastatin With Atorvastatin in Increasing High Density Lipoprotein - Cholesterol (HDL-C) and Adiponectin in Patients With Dyslipidemia and Coronary Artery Disease (CAD)

Completed·KKumamoto University·Phase 4·NCT00861861·129 enrolled

Pharmacodynamic Comparison of Rosuvastatin Versus Atorvastatin on Platelet Reactivity in Patients With Coronary Artery Disease on Dual Antiplatelet Therapy With New P2Y12 Inhibitors (Trial gRANADa)

Unknown status·UUniversity of Roma La Sapienza·Phase 4·NCT02030054·150 enrolled

Intensive Statin Treatment in Chinese Coronary Artery Disease Patients Undergoing PCI

Completed·PPeking University First Hospital·Phase 4·NCT01293097·2,884 enrolled

Show 2 more trials

EASEGO Study: Doubling of Atorvastatin/Simvastatin or INEGY in Patients With Hypercholesterolemia and Coronary Artery Disease(CAD)(0653A-089)

Completed·OOrganon and Co·Phase 4·NCT00166530·367 enrolled

Effect of Atorvastatin on Fractional Flow Reserve in Coronary Artery Disease

Completed·KKeimyung University Dongsan Medical Center·Phase 3·NCT01946815·119 enrolled

Heart Disease4 trials

Study On Liprimar (Atorvastatin) In Patients With Coronary Heart Disease (CHD) And High Risk Of Cardiovascular Complications

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.··NCT00993915·687 enrolled

A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease

Completed· Pfizer logo

Pfizer·Phase 3·NCT00134173·1,100 enrolled

Ezetimibe and Atorvastatin vs. Atorvastatin in Patients Age 65 and Older at High Risk for Coronary Heart Disease (CHD)(0653-112)

Completed·OOrganon and Co·Phase 3·NCT00418834·1,053 enrolled

Show 1 more trial

Atorvastatin Versus Simvastatin In The Prevention Of Coronary Heart Disease (CHD) In Patients With Known CHD

Completed· Pfizer logo

Pfizer·Phase 4·NCT00159835·8,600 enrolled

Metabolic Syndrome4 trials

COMETS - Compare the Efficacy of Rosuvastatin With Atorvastatin and Placebo in the Treatment of Non-Diabetic, Non-Atheroscleric, Metabolic Syndrome Subjects

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654485·940 enrolled

ROMEO (Rosuvastatin in Metabolic syndrOme)

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00395486·258 enrolled

Ezetimibe (+) Simvastatin vs. Atorvastatin Comparative Study in DM or Metabolic Syndrome Patients (0653A-093)

Completed·OOrganon and Co·Phase 4·NCT00157924·190 enrolled

Show 1 more trial

Prothrombotic Inflammatory Markers in Women With Metabolic Syndrome - Effect of Atorvastatin

Completed·UUniversity of Rochester·Phase 1/2·NCT01785615·116 enrolled

Overweight3 trials

A Study to Learn How the Study Medicine Danuglipron is Taken Up Into the Blood and If Danuglipron Changes How the Body Processes Other Study Medicines (Atorvastatin and Rosuvastatin) in Healthy Adults Who Are Overweight or Obese

Completed· Pfizer logo

Pfizer·Phase 1·NCT06567327·82 enrolled

A Study to Evaluate LY3202328 in Overweight Healthy Participants and Dyslipidemia

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT02714569·60 enrolled

Safety and Benefit of MBX-8025 With and Without Commonly Used Statins in Moderately Overweight Patients With High Cholesterol

Completed· Gilead logo

Gilead·Phase 2·NCT00701883·183 enrolled

Toxicity3 trials

Preventing Anthracycline Cardiovascular Toxicity With Statins (PREVENT)

Completed·WWake Forest University Health Sciences·Phase 2·NCT01988571·279 enrolled

Differences in Atorvastatin Metabolite Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity

Completed·OOslo University Hospital·Phase 4·NCT00199745·53 enrolled

Investigations on Differences in Atorvastatin Metabolites Ratios as a Diagnostic Tool in Detecting Atorvastatin Induced Myotoxicity

Completed·UUniversity of Oslo School of Pharmacy·Phase 4·NCT00414531·53 enrolled

Cardiovascular3 trials

Post-Operative Biomarker-Guided Precision Medicine For Cardiovascular Risk Reduction

Recruiting·NNYU Langone Health·Phase 1·NCT06961630·50 enrolled

Pharmacodynamic Equivalence of Ramipril 10 mg and Atorvastatin 40 mg Administered as a Cardiovascular (CV) Polypill Acetylsalicylic Acid-Atorvastatin-Ramipril (AAR) as Compared to Monotherapy

Unknown status·FFerrer Internacional S.A.·Phase 2·NCT02791958·528 enrolled

AtorvaStatin Postpartum and Reduction of Cardiovascular risK

Recruiting·OOhio State University·Phase 4·NCT06632379·76 enrolled

Cardiovascular Disease3 trials

Lipoprotein(a) Levels in Patients With Atherosclerotic Cardiovascular Diseases in Russia

Recruiting· Novartis logo

Novartis··NCT06858332·2,382 enrolled

The Role of Statins in the Prevention of Contrast-induced Acute Kidney Injury in Patients With Cardiovascular Diseases

Completed·II.M. Sechenov First Moscow State Medical University·N/A·NCT04666389·150 enrolled

Atorvastatin Treatment to Attenuate the Progression of Cardiovascular Disease in Hemodialysis Patients

Completed·EErcan OK·Phase 3·NCT00481364·446 enrolled

Hypercholesterolaemia2 trials

Treatment of Hypercholesterolaemia in South Asian Subjects (IRIS)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00654225·2,340 enrolled

Rosuvastatin Versus Atorvastatin in the Treatment of Hypercholesterolaemia in African American Subjects(ARIES)

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00653744·1,700 enrolled

Diabetes Mellitus2 trials

Follow-On Study of Pitavastatin Versus Atorvastatin in Patients With Type II Diabetes Mellitus and Combined Dyslipidemia

Completed·KKowa Research Europe·Phase 3·NCT00344370·214 enrolled

Atorvastatin and LDL Profile in Non-Insulin Dependent Diabetes Mellitus

Terminated·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00640549·41 enrolled

Diastolic Heart Failure2 trials

Effects of Statin Therapy on Vascular Properties and Outcomes in Diastolic Heart Failure Patients

Terminated·UUniversity of Wisconsin, Madison·N/A·NCT00585611·1 enrolled

The Effect of Eplerenone and Atorvastatin on Markers of Collagen Turnover in Diastolic Heart Failure

Completed·SSt Vincent's University Hospital, Ireland·N/A·NCT00505336·43 enrolled

Atherosclerotic Plaque2 trials

Diagnosis and Therapy of Vulnerable Atherosclerotic Plaque

Completed·—·N/A·NCT00636766·300 enrolled

Assessment of Change in Atherosclerotic Plaque by Serial CCTA

Unknown status·YYonsei University··NCT03414840·400 enrolled

Efficacy and Safety2 trials

Evaluation of the Efficacy and Safety of Rosuvastatin 5 mg Versus Pravastatin 40 mg and Atorvastatin 10 mg in Type IIa and IIb Hypercholesterolaemic Patients

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00631189·668 enrolled

Efficacy and Safety of Gemcabene in Hypercholesterolemic Patients as Monotherapy or in Combination With Atorvastatin

Completed·NNeuroBo Pharmaceuticals Inc.·Phase 2·NCT02591836·277 enrolled

Dyslipidemia2 trials

Pharmacokinetics of Rosuvastatin and Atorvastatin in Pediatric Dyslipidemia Patients

Completed·—·Phase 1·NCT02364258·28 enrolled

Characterization of Multi-dose RVX000222 in Combination With Statin Treatment in Dyslipidemia

Terminated·RResverlogix Corp·Phase 2·NCT01863225·13 enrolled

Complication2 trials

Lowering the Risk of Operative Complications Using Atorvastatin Loading Dose

Completed·HHospital do Coracao·Phase 3·NCT01543555·648 enrolled

Study of Atorvastatin Versus Placebo to Reduce Cardiopulmonary Complications After Thoracic Surgery

Completed·MMemorial Sloan Kettering Cancer Center·N/A·NCT00375518·162 enrolled

Hyperlipidemia2 trials

An Open-Label Study to Compare the Lipid Effects of Niacin ER and Simvastatin (NS) to Atorvastatin in Subjects With Hyperlipidemia or Mixed Dyslipidemia (SUPREME)

Completed·AAbbott·Phase 3·NCT00465088·199 enrolled

IMPAACT P1063: Safety and Effectiveness of Atorvastatin in HIV Infected Children and Adolescents With Hyperlipidemia

Terminated·IInternational Maternal Pediatric Adolescent AIDS Clinical Trials Group·Phase 1/2·NCT00663234·28 enrolled

Chronic Kidney Disease2 trials

Effect of Pitavastatin on Erythrocyte Membrane Fatty Acid Contents in Patients With Chronic Kidney Disease

Completed·—·Phase 4·NCT02863185·45 enrolled

The Effect of Atorvastatin on Endothelial Cell Dysfunction in Chronic Kidney Disease

Terminated·—·Phase 4·NCT02133534·1 enrolled

Gastric Emptying2 trials

Influence of HRS9531 on Gastric Emptying and Pharmacokinetics of Metformin, Atorvastatin, Warfarin, and Digoxin in Healthy Subjects

Completed·FFujian Shengdi Pharmaceutical Co., Ltd.·Phase 1·NCT06723691·57 enrolled

Study of the Effects of ITCA 650 on Gastric Emptying and Interaction of ITCA 650 on 4 Commonly Studied Drugs

Completed·IIntarcia Therapeutics·Phase 1·NCT02641899·33 enrolled

Endothelial Function2 trials

Statins and Endothelial Function in Patients With Coarctation of the Aorta

Terminated·UUniversity of California, San Francisco·Phase 4·NCT00767572·12 enrolled

The Effect of Ticagrelor With or Without Atorvastatin on Endothelial Function in Healthy Males

Completed·MMedical University of Vienna·Phase 4·NCT02910778·32 enrolled

Symptomatic Intracranial Atherosclerotic Stenosis2 trials

Extra Alirocumab in Addition to Statin Therapy in Asymptomatic Intracranial Atherosclerotic Stenosis (EAST-aICAS)

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 3·NCT06080256·80 enrolled

Evolocumab Added to Statin Therapy in Symptomatic Intracranial Atherosclerotic Stenosis (EAST-ICAS)

Unknown status·TThe First Affiliated Hospital with Nanjing Medical University·Phase 3·NCT05741086·80 enrolled

Systemic Inflammatory Response Syndrome1 trial

Effect of Atorvastatin as a Renal Protection in Patients With Systemic Inflammatory Response Syndrome Using Renal Arterial Resistive Index

Unknown status·MMinia University·Phase 1·NCT05946122·106 enrolled

Type 1 Diabetic1 trial

Prediction and Prevention of Asymptomatic Cardiovascular Insult in Type 1 Diabetic Children: Comparative Effectiveness of Cardioprotective Drugs

Completed·TTanta University·N/A·NCT03660293·150 enrolled

Hepatitis B1 trial

Effects of Short-term Atorvastatin Treatment on Vaccination Efficacy in Nonresponder Persons to Hepatitis B Vaccine

Unknown status·NNematollah Jonaidi Jafari·Phase 4·NCT01548326·52 enrolled

ART1 trial

A Study of LY3478045 in Healthy Participants

Completed· Eli Lilly logo

Eli Lilly·Phase 1·NCT04270370·72 enrolled

Metabolism1 trial

Regulation of Lipoprotein Metabolism in Obese Men

Completed·TThe University of Western Australia·Phase 3·NCT00392717·48 enrolled

Psoriasis1 trial

Efficacy of Atorvastatin as Adjunctive Treatment for Chronic Plaque Type Psoriasis

Completed·PPhilippine Dermatological Society·Phase 2·NCT02432040·28 enrolled

Carotid Plaque1 trial

Evaluation of Atorvastatin Treatment on Carotid Plaque.

Terminated·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 3·NCT00343655·160 enrolled

Inflammation1 trial

Impact of Chronic Statin Use During Surgery on Inflammation and Infection Rates

Completed·OOttawa Hospital Research Institute··NCT00967252·50 enrolled

Type 1 Diabetes Mellitus1 trial

Atorvastatin in New Onset Type 1 Diabetes Mellitus (T1DM)

Completed·—·Phase 2·NCT00529191·40 enrolled

Overweight or Obese1 trial

A Study to Evaluate the Drug-drug Interactions (DDIs) of IBI362 With Metformin, Warfarin, Atorvastatin, Digoxin in Overweight or Obese Subjects

Completed· Innovent Biologics (Suzhou) Co. Ltd. logo

Innovent Biologics (Suzhou) Co. Ltd.·Phase 1·NCT05815680·48 enrolled

Exercise1 trial

Measuring Oncological Value of Exercise and Statin

Recruiting·TTampere University Hospital·Phase 3·NCT05796973·240 enrolled

Type 2 Diabetes Mellitus1 trial

Efficacy and Safety Study of Pitavastatin Compared to atoRvastatin in Type 2 dIabeTes Mellitus With Hypercholesterolemia

Completed·JJW Pharmaceutical·Phase 4·NCT00889226·161 enrolled

Immune Response1 trial

The Effect of Short-term Atorvastatin Treatment on Immune Responses to Pneumovax 23

Completed·UUniversity of Florida·Phase 1·NCT02097589·33 enrolled

Pilot Study1 trial

Cerebral and Peripheral Perfusion Pilot Study

Completed·UUniversity of Wisconsin, Madison·Phase 2·NCT00751907·16 enrolled

Erectile Dysfunction1 trial

Pentoxifylline, Atorvastatin, and Vitamin E in Treating Patients With Erectile Dysfunction After Radiation Therapy for Prostate Cancer

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT03830164·14 enrolled

Aspirin1 trial

Aspirin Statins Or Both For The Reduction Of Thrombin Generation In Diabetic People

Completed·FFundacion GESICA·Phase 4·NCT00793754·30 enrolled

Genetic Polymorphism1 trial

Effect of CYP3A Genetic Polymorphisms on the Pharmacokinetics of Atorvastatin

Completed·—·Phase 1·NCT00973986·20 enrolled

Mood Disorder1 trial

Anti-inflmmation Treatment in Mood Disorder and Deep Learning Prediction Model

Unknown status·TTaipei Veterans General Hospital, Taiwan·Phase 4·NCT04685642·180 enrolled

Mesenchymal Stem Cells1 trial

Transplantation Efficacy of Autologous Bone Marrow Mesenchymal Stem Cells With Intensive Atorvastatin in AMI Patients

Unknown status·YYuejin Yang·Phase 2·NCT03047772·124 enrolled

Retinal Vein Occlusion1 trial

Atorvastatin for the Treatment of Retinal Vein Occlusion

Unknown status·UUniversity of Toronto·Phase 3·NCT00517257·180 enrolled

GLP-11 trial

The Effect of HMG-CoA Reductase Inhibition on Postprandial GLP-1 Secretion

Completed·UUniversity Hospital, Gentofte, Copenhagen·N/A·NCT03018444·15 enrolled

Combination Therapy1 trial

Study of Atorvastatin/Fenofibrate (LCP-AtorFen) Combination Therapy in Dyslipidemia

Completed·VVeloxis Pharmaceuticals·Phase 2·NCT00504829·220 enrolled

Type 1 Diabetes1 trial

Treatment Effects of Atorvastatin on Hemostasis and Skin Microcirculation in Patients With Type 1 Diabetes

Completed·KKarolinska Institutet·Phase 4·NCT01497912·20 enrolled

Calcification1 trial

CARE-2 (Calcium Acetate [PhosLo®]/Sevelamer[Renagel®] Evaluation Study 2) for Heart Calcification in Dialysis Patients

Completed·NNabi Biopharmaceuticals·Phase 4·NCT00211939·203 enrolled

Trial1 trial

LIpitor and biGuanide to Androgen Delay Trial

Withdrawn·UUniversity Health Network, Toronto·Phase 2·NCT02497638

Ischemic stroke1 trial

Blood Pressure Variability and the Prognosis of Ischemic Stroke With Intracranial Artery Stenosis

Unknown status·RRenJi Hospital·N/A·NCT01665235·200 enrolled

Clinical Trial1 trial

Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects Who Are Intolerant to Statins

Completed· Pfizer logo

Pfizer·Phase 3·NCT02135029·184 enrolled

Dual Antiplatelet Therapy1 trial

Statin and Dual Antiplatelet Therapy to Prevent Early Neurological Deterioration in Branch Atheromatous Disease

Completed·—·Phase 2·NCT04824911·376 enrolled

Platelet Inhibition1 trial

Effect of Platelet Inhibition and / or Lipid Lowering in Non-ACS-patients With Positive Troponin

Terminated·DDr. med. Mahir Karakas·Phase 3·NCT03820466·68 enrolled

Hypertension1 trial

Comparing Amlodipine/Atorvastatin Co-Administration To Amlodipine Alone In Patients With Hypertension And Dyslipidemia

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 4·NCT00174330·330 enrolled

Midazolam1 trial

Effects of Statins on the Pharmacokinetics for Midazolam in Healthy Volunteers

Completed·HHamamatsu University·N/A·NCT00716846·11 enrolled

Imaging1 trial

CRESTOR Athero Imaging Head to Head IVUS Study

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00620542·2,333 enrolled

Vaccine Response1 trial

Systems Biological Assessment of Statin Effect on Vaccine Responses

Completed·EEmory University·Phase 4·NCT06024096·63 enrolled

COVID-191 trial

HElping Alleviate the Longer-term Consequences of COVID-19 (HEAL-COVID)

Unknown status·—·Phase 3·NCT04801940·2,631 enrolled

Alcoholic Fatty Liver Disease1 trial

Assessment of Endothelial Function in Patients With Non Alcoholic Fatty Liver Disease and the Impact of Statin Treatment

Withdrawn·SSheba Medical Center·N/A·NCT01987310

Systemic Lupus Erythematosus1 trial

An Open Labeled Pilot Study of Atorvastatin in Systemic Lupus Erythematosus

Unknown status·—·Phase 2/3·NCT00432354·40 enrolled

Alagille Syndrome1 trial

Atorvastatin Therapy on Xanthoma in Alagille Syndrome

Recruiting·—·Phase 4·NCT05488067·10 enrolled

Cardiotoxicity1 trial

STOP-CA (Statins TO Prevent the Cardiotoxicity From Anthracyclines)

Completed·MMassachusetts General Hospital·Phase 2·NCT02943590·300 enrolled

Fasting Conditions1 trial

A Bioequivalence Study Of 80 Mg Atorvastatin Calcium Tablets Versus 80 Mg Lipitor® Tablets Under Fasting Conditions.

Completed·RRanbaxy Laboratories Limited·Phase 1·NCT01499758·80 enrolled

Cardiovascular Events1 trial

Effect of RVX000222 on Time to Major Adverse Cardiovascular Events in High-Risk T2DM Subjects With CAD

Completed·RResverlogix Corp·Phase 3·NCT02586155·2,425 enrolled

Atrial Fibrillation1 trial

Fish Oil Versus Statins Versus Placebos in Reducing Atrial Fibrillation in Patients Undergoing Thoracic Surgery for Lung Cancer

Terminated·MM.D. Anderson Cancer Center·Phase 2/3·NCT01259284·2 enrolled

Chronic Asthma1 trial

Trial to Evaluate the Effect of Statins on Asthma Control of Patients With Chronic Asthma

Completed·UUniversity of Glasgow·Phase 2/3·NCT00126048·54 enrolled

Breast Cancer1 trial

Statins and Breast Cancer Biomarkers

Unknown status·UUniversity of Vermont·Phase 2·NCT00914017·100 enrolled

Acute Kidney Injury1 trial

Atorvastatin Versus Rosuvastatin on Contrast Induced Acute Kidney Injury (PRATO-ACS 2)

Completed·CCentro Cardiopatici Toscani·Phase 4·NCT01870804·760 enrolled

Hepatocellular Carcinoma1 trial

Statin for Preventing Hepatocellular Carcinoma Recurrence After Curative Treatment

Active, not recruiting·—·Phase 4·NCT03024684·240 enrolled

Plaque1 trial

CT COMPARE: CT Coronary Angiography to Measure Plaque Reduction

Terminated·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 4·NCT02740699·79 enrolled

Type 2 Diabetic Patients1 trial

Type 2 Diabetic Patients Maintained on Statin Therapy

Completed·—·Phase 4·NCT03784703·160 enrolled

Homozygous Familial Hypercholesterolemia1 trial

Safety and Tolerability Study of Ezetimibe (SCH 058235/MK-0653) Plus Atorvastatin or Simvastatin in Homozygous Familial Hypercholesterolemia (P01417/MK-0653-019)

Completed·OOrganon and Co·Phase 3·NCT03885921·44 enrolled

Statin1 trial

KF2023#1-Trial: Influence of Statin Intake on Cellular Readouts

Recruiting·MMikko Niemi·Phase 1·NCT06469450·15 enrolled

Treatment1 trial

Combined Effects of Non-statin Treatments on Apolipoprotein A-I Up-Regulation (CENTAUR): A Feasibility Study

Completed·UUniversity of Pennsylvania·Phase 2·NCT00728910·25 enrolled

Pregnancy1 trial

Atorvastatin as a Potential Adjunct to Misoprostol for Termination of Pregnancy

Completed·UUniversity of Utah·Phase 1·NCT05342974·9 enrolled

Oxidative Stress1 trial

Effect of Statins on Oxidative Stress and Endothelial Progenitor Cells

Completed·EEmory University·Phase 2·NCT00166036·36 enrolled

Relapsing-Remitting Multiple Sclerosis1 trial

Atorvastatin 40 mg in Patients With Relapsing-Remitting Multiple Sclerosis Treated With Interferon-Beta-1b

Completed·IInsel Gruppe AG, University Hospital Bern·Phase 2·NCT00942591·77 enrolled

Necrosis1 trial

Effects of Short Term, High Dose Atorvastatin Therapy on Periprocedural Myonecrosis and Platelet Inhibition After Percutaneous Coronary Intervention (PCI)

Terminated·IIndiana University School of Medicine·N/A·NCT00979940·60 enrolled

Blood Pressure1 trial

Effects of Atorvastatin on Blood Pressure and Urinary Albumin Excretion

Completed·—·N/A·NCT01126684·50 enrolled

Endometriosis1 trial

MicroRNA Activation of LOX-1 Mechanisms in Endometriosis

Terminated·PPenn State University·Phase 4·NCT05331053·6 enrolled

Chronic Periodontitis1 trial

Locally Delivered Atorvastatin & Rosuvastatin for Treatment of Furcation Defects in Chronic Periodontitis

Completed·GGovernment Dental College and Research Institute, Bangalore·Phase 2/3·NCT02800902·90 enrolled

ST Elevation Myocardial Infarction1 trial

Efficacy of High Dose atorvaSTATIN Loading Before Primary Percutaneous Coronary Intervention in ST Elevation Myocardial Infarction (STATIN STEMI)

Completed·YYonsei University·Phase 4·NCT00808717·170 enrolled

Elderly Patients1 trial

Effect of Atorvastatin Versus Rosuvastatin Intensive Statin Regimens on Chinese Elderly Patients Undergoing PCI

Unknown status·—·Phase 4·NCT01646307·1,000 enrolled

Myalgia1 trial

Study of the Safety and Tolerability Associated With PPD10558 Versus Atorvastatin in Patients Previously Intolerant to Statins Due to Statin-associated Myalgia (SAM)

Completed·FFuriex Pharmaceuticals, Inc·Phase 2·NCT01279590·282 enrolled

Hematoma1 trial

The Clinical Study of Atorvastatin and Dexamethasone on Treatment for Chronic Subdural Hematoma in the Patients With Coagulation Disorders

Unknown status·OOriental Neurosurgery Evidence-Based-Study Team·Phase 2·NCT02192320·60 enrolled

Abnormal Glucose Metabolism1 trial

Comparison of Atorvastatin and Pitavastatin on the Effect of HbA1c in AMI Patients With Abnormal Glucose Metabolism

Unknown status·—·Phase 4·NCT04945122·900 enrolled

Renal Cell Carcinoma1 trial

Zoledronate With Atorvastatin in Renal Cell Carcinoma

Completed·MM.D. Anderson Cancer Center·Phase 2·NCT00490698·11 enrolled

Aneurysm1 trial

Statin Treatment for UnruptureD Intracranial anEurysms Study

Unknown status·BBeijing Neurosurgical Institute·Phase 2·NCT04149483·60 enrolled

Non-Alcoholic Steatohepatitis1 trial

Atorvastatin, L-Carnitine and Non-Alcoholic Steatohepatitis

Unknown status·TTehran University of Medical Sciences·Phase 2·NCT01617772·440 enrolled

Ischemia1 trial

Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers

Completed·KKarolinska Institutet·Phase 1·NCT02286544·36 enrolled

Endothelial Dysfunction1 trial

Effect of a Fibrate and a Statin on Endothelial Dysfunction

Terminated·—·N/A·NCT00491400·28 enrolled

Cholesterol1 trial

A Study in People With High Cholesterol

Completed· Eli Lilly logo

Eli Lilly·Phase 2·NCT00133380·300 enrolled

Function1 trial

Effect of Chronic Statin and Viagra Therapy in Persons With Endothelial Cell Dysfunction

Withdrawn·MMayo Clinic·N/A·NCT00587379

Type 2 Diabetes1 trial

Effect of Atorvastatin on Vascular Inflammation in Type 2 Diabetes

Withdrawn·KKorea University·N/A·NCT00932048

Nephropathy1 trial

Atorvastatin Effect on Contrast Induced Nephropathy in Diabetic Patients Undergoing Elective Coronary Intervention

Completed·MMohamed Abdelfatah·Phase 4·NCT04375787·200 enrolled

Nephrotic Syndrome1 trial

Effect of PCSK9-Antibody (Alirocumab) on Dyslipidemia Secondary to Nephrotic Syndrome

Terminated·GGloria Vega·Phase 2·NCT03004001·3 enrolled

Optical Coherence Tomography1 trial

Evaluation of Statin-induced Lipid-rich Plaque Progression by Optical Coherence Tomography (OCT) Combined With Intravascular Ultrasound (IVUS)

Completed·HHarbin Medical University·Phase 4·NCT01023607·120 enrolled

Pediatric1 trial

Bioequivalence Study Of Pediatric Appropriate Formulation

Completed·PPfizer's Upjohn has merged with Mylan to form Viatris Inc.·Phase 1·NCT00758004·76 enrolled

Effectiveness1 trial

A Study to Evaluate the Effectiveness of Ezetimibe/Atorvastatin 10 mg/20 mg Combination Tablet Compared to Marketed Ezetimibe 10 mg and Atorvastatin 20 mg Tablets in Participants With High Cholesterol (MK-0653C-185 AM1)

Completed·OOrganon and Co·Phase 3·NCT01370590·406 enrolled

Immune Thrombocytopenia1 trial

The Combination of Atorvastatin, Acetylcysteine and Danazol as the Treatment of Steroid-resistant/Relapse Immune Thrombocytopenia

Unknown status·PPeking University People's Hospital·Phase 1/2·NCT03460808·200 enrolled

Pulmonary Sarcoidosis1 trial

Atorvastatin to Treat Pulmonary Sarcoidosis

Completed·NNational Heart, Lung, and Blood Institute (NHLBI)·Phase 2·NCT00279708·55 enrolled

Statins1 trial

Statins and CPAP in Adipose Tissue of OSA

Completed·MMayo Clinic·Phase 1/2·NCT03308578·50 enrolled

Acute Graft Versus Host Disease1 trial

Safety & Efficacy of Atorvastatin for Prophylaxis of Acute Graft Versus Host Disease in Patients With Hematological Malignancies HLA- Donor Hematopoietic Stem Cell Transplantation

Completed·OOhio State University Comprehensive Cancer Center·Phase 2·NCT01491958·40 enrolled

Immune Checkpoint Inhibitor1 trial

Statins to Prevent Immune Checkpoint Inhibitor-induced PRogression of AtherosLerosis

Not yet recruiting·EErasmus Medical Center·Phase 4·NCT06785974·140 enrolled

Interaction1 trial

A Phase 1 Study to Evaluate the Drug-Drug Interaction Potential Between ALG-055009 and Statin Therapy(Ies)

Completed·AAligos Therapeutics·Phase 1·NCT06191991·14 enrolled

Phase 11 trial

A 2-Part, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, and Pharmacodynamics of CAT-2054 in Healthy Subjects

Completed·CCatabasis Pharmaceuticals·Phase 1·NCT02374047·118 enrolled

Unspecified3 trials

Pemvidutide (ALT-801) DDI Study in Healthy Volunteers

Completed· Altimmune logo

Altimmune·Phase 1·NCT04972396·40 enrolled

Diazoxide Choline Controlled-Release Tablet (DCCR) for Very High Triglycerides

Withdrawn·EEssentialis, Inc.·Phase 3·NCT00973271

A Study to Determine the Degree of Additional Reduction in CV Risk in Lowering LDL Below Minimum Target Levels

Completed· Pfizer logo

Pfizer·Phase 4·NCT00327691·8,600 enrolled

Regulatory

FDA Approval Timeline[5]

Dec 17, 1996

LIPITOR

NDA NDA020702

Feb 1, 2023

ATORVALIQ

NDA NDA213260

Sources

References

[1]
ClinicalTrials.gov — 645 trial records for atorvastatin. U.S. National Library of Medicine, National Institutes of Health.
[2]
MedlinePlus Drug Information — Lipitor drug information. U.S. National Library of Medicine, National Institutes of Health.
[3]
ChEMBL — atorvastatin compound record. European Bioinformatics Institute (EMBL-EBI).
[4]
Open Targets Platform — Drug–disease associations for atorvastatin. EMBL-EBI & Wellcome Sanger Institute.
[5]
OpenFDA — FDA approval records (NDA NDA213260). U.S. Food & Drug Administration.
[6]
FDA Orange Book — Patent and exclusivity data for Lipitor. U.S. Food & Drug Administration.
[7]
SEC EDGAR — Pfizer's Upjohn has merged with Mylan to form Viatris Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Mechanism of Action: HMG-Coa Reductase Inhibitor[3]
Modality: Small molecule[3]
Highest Phase: Approved[1]
Company: PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Patent Landscape[6]

Patent Cliff

Jun 7, 2037

Earliest patent expiration — generic entry possible after this date

Patent #Expires

11654106Jun 7, 2037

11925704Jun 7, 2037

12370136Jun 7, 2037

12168069Jun 7, 2037

11369567Jun 7, 2037

1 more patents

12599553Jun 7, 2037