Huaier Granule

Phase 3Small molecule

QQidong Gaitianli Medicines Co., Ltd

Huaier Granule is one of 325 small molecule programs targeting Pancreatic Cancer. It is currently in Phase 3.

Indications

Total Trials

Active Trials

324

Competitors

Pipeline

Status by Indication[3][1]

Indication

Pancreatic CancerRecruiting

Fallopian Tube CancerActive, not recruiting

Ovarian CancerActive, not recruiting

Non-Small Cell Lung CancerNot yet recruiting

Lung CancerNot yet recruiting

Triple-Negative Breast CancerRecruiting

Breast CancerNot yet recruiting

Colorectal CancerNot yet recruiting

Gastric CancerNot yet recruiting

Membranous NephropathyRecruiting

Pancreatic CancerPhase 3

Recruiting

Fallopian Tube CancerPreclinical

Active, not recruiting

Ovarian CancerPreclinical

Active, not recruiting

Non-Small Cell Lung CancerPhase 3

Not yet recruiting

Lung CancerPhase 3

Not yet recruiting

Triple-Negative Breast CancerPhase 3

Recruiting

Breast CancerPhase 3

Not yet recruiting

Colorectal CancerPhase 3

Not yet recruiting

Gastric CancerPhase 3

Not yet recruiting

Membranous NephropathyPhase 3

Recruiting

Competition

Competitive Landscape

744 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Huaier Granule

QQidong Gaitianli Medicines Co., Ltd

Phase 3

4 2

Lexiscan

Astellas

Preclinical

1 3

Blenoxane

Bristol-Myers Squibb

Preclinical

1 4

Duragesic

CCephalon

Preclinical

1 5

Sporanox

SSebela Pharmaceuticals Development LLC

Preclinical

1 6

Neoadjuvant Treatment

SShanghai Zhongshan Hospital

Preclinical

1 7

Tianeptine

Pfizer

Preclinical

1 8

Diuretic

RReprieve Cardiovascular, Inc

Preclinical

1 9

Recombinant Human Endostatin

PPeking University Third Hospital

Preclinical

1 10

Metfomin

UUniversity of Texas Southwestern Medical Center

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2027

Post-ApprovalRecruiting

Membranous Nephropathy

NCT05839314

Q4 2027

Post-ApprovalNot yet recruiting

Breast Cancer

NCT05860907

Q1 2028

Post-ApprovalNot yet recruiting

Breast Cancer

NCT05871437

Post-ApprovalNot yet recruiting

Lung Cancer

NCT07358520

Post-ApprovalRecruiting

Pancreatic Cancer

NCT06368063

Q2 2028

Phase 2Not yet recruiting

Proteinuria

NCT07355361

Clinical

Trials by Indication[1]

Colorectal Cancer4 trials

To Explore the Effect of Huaier Granule on the Negative Conversion Rate After the CEA Level Increases Again After Colorectal Cancer Surgery

Not yet recruiting·FFudan University·Phase 4·NCT06665334·134 enrolled

Huaier Granule As Adjuvant Therapy for Colorectal Cancer After Radical Surgery

Unknown status·SSixth Affiliated Hospital, Sun Yat-sen University·Phase 3·NCT02796820·230 enrolled

Adjuvant Chemotherapy Combined With Huaier Granule for Treating High-risk Stage II, Stage III Colorectal Cancer

Unknown status·SSixth Affiliated Hospital, Sun Yat-sen University·Phase 3·NCT02785146·230 enrolled

Show 1 more trial

Prevention of Recurrence and Metastasis of Colorectal Cancer by Comparing Huaier With Capecitabine Monotherapy

Recruiting·FFudan University·Phase 4·NCT06090994·756 enrolled

Breast Cancer4 trials

Clinical Study of Huaier Granules in Patients With Advanced Breast Cancer Without Visceral Metastasis

Not yet recruiting·FFudan University·Phase 4·NCT05860907·384 enrolled

Huaier Granule in Treating Women With Triple Negative Breast Cancer

Unknown status·SShandong University·Phase 4·NCT02615457·300 enrolled

Randomized Controlled Clinical Study on the Reduction of Tumor Marker Levels in Breast Cancer Patients by Huaier Granules

Not yet recruiting·FFudan University·Phase 4·NCT05871437·232 enrolled

Show 1 more trial

Neoadjuvant Chemotherapy With or Without Huaier Granule in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery

Unknown status·SShandong University·Phase 4·NCT02627248·200 enrolled

Non-Small Cell Lung Cancer3 trials

Observation on the Therapeutic Effect of Huaier Granules in the Adjuvant Treatment of Non-small Cell Lung Cancer After Radical Surgery

Recruiting·LLiaoning Cancer Hospital & Institute··NCT06109454·240 enrolled

Clinical Efficacy and Safety of Microwave Ablation Combined With Huaier Granules in Patients With Inoperable Stage IA Non-Small Cell Lung Cancer: A Prospective, Single-Center, Randomized Controlled Clinical Trial

Not yet recruiting·XXin Ye·Phase 3·NCT07197853·180 enrolled

Huaier Granule for Prevention of Recurrence and Metastasis of Stage II and III Non-small Cell Lung Cancer (NSCLC)

Terminated·QQidong Gaitianli Medicines Co., Ltd·N/A·NCT03198117·6 enrolled

Pancreatic Cancer2 trials

The Study of Huaier Granule in Postoperative Adjuvant Therapy of Resectable Pancreatic Cancer

Recruiting·XXi'an Jiaotong University·Phase 4·NCT06368063·642 enrolled

Clinical Study of Huaier Granule in the Treatment of Unresectable Pancreatic Cancer

Not yet recruiting·XXi'an Jiaotong University·Phase 4·NCT06387368·488 enrolled

Metastasis1 trial

Huaier Granule for Prevention of Recurrence and Metastasis of Hepatocarcinoma After Radical Hepatectomy

Completed·QQidong Gaitianli Medicines Co., Ltd·Phase 4·NCT01770431·1,044 enrolled

10 more indications

Proteinuria1 trial

Huaier Granule and Proteinuria

Not yet recruiting·FFudan University·Phase 2·NCT07355361·120 enrolled

Gastric Cancer1 trial

Effect and Safety of Huaier Granule Versus SOX Regimen in Gastric Cancer Patients

Not yet recruiting·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·Phase 4·NCT05498766·702 enrolled

Fallopian Tube Cancer1 trial

Huaier Granule in Patients With Stage I Primary Ovarian Fallopian Tube Cancer After Peritoneal Cancer

Unknown status·RRuijin Hospital·N/A·NCT05792254·30 enrolled

Disease Progression1 trial

Huaier Granule for Prevention of Disease Progression of Hepatocarcinoma After Non-radical Hepatectomy

Terminated·QQidong Gaitianli Medicines Co., Ltd·Phase 4·NCT01760616·790 enrolled

Toxicity1 trial

Effect of Huaier Granule on Nephrotoxicity Associated With Targeted Therapy for Advanced Hepatobiliary Malignancies.

Completed·FFudan University·Phase 2·NCT05673824·76 enrolled

Ovarian Cancer1 trial

Huaier Granule in Combination With Nilaparil in Therapy Patients With Stage III/IV BRCA Wild-type Ovarian Cancer

Unknown status·RRuijin Hospital·N/A·NCT05749211·59 enrolled

Membranous Nephropathy1 trial

Effect of Huaier Granule on the Treatment of Idiopathic Membranous Nephropathy

Recruiting·—·Phase 4·NCT05839314·480 enrolled

Triple-Negative Breast Cancer1 trial

Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer

Recruiting·FFudan University·Phase 4·NCT04790305·1,072 enrolled

COVID-191 trial

The Efficacy and Safety of Huai er in the Adjuvant Treatment of COVID-19

Unknown status·TTongji Hospital·Phase 2/3·NCT04291053·550 enrolled

Lung Cancer1 trial

Clinical Study on the Use of Huaier Granules for the Treatment of Proteinuria Related to Bevacizumab and Anlotinib in Lung Cancer Patients

Not yet recruiting·FFudan University·Phase 4·NCT07358520·40 enrolled

Sources

References

[1]
ClinicalTrials.gov — 24 trial records for Huaier Granule. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Huaier Granule compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Huaier Granule. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Qidong Gaitianli Medicines Co., Ltd company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: QQidong Gaitianli Medicines Co., Ltd

Huaier Granule

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2027

Q4 2027

Q1 2028

Q2 2028

Trials by Indication[1]

Colorectal Cancer4 trials

Breast Cancer4 trials

Non-Small Cell Lung Cancer3 trials

Pancreatic Cancer2 trials

Metastasis1 trial

Proteinuria1 trial

Gastric Cancer1 trial

Fallopian Tube Cancer1 trial

Disease Progression1 trial

Toxicity1 trial

Ovarian Cancer1 trial

Membranous Nephropathy1 trial

Triple-Negative Breast Cancer1 trial

COVID-191 trial

Lung Cancer1 trial

References

Drug Info

Quick Facts

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