isolated limb perfusion

Phase 3Small molecule

MMemorial Sloan Kettering Cancer Center

isolated limb perfusion is one of 73 small molecule programs targeting Melanoma. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

MelanomaActive, not recruiting

Soft Tissue SarcomaActive, not recruiting

MelanomaPhase 3

Active, not recruiting

Soft Tissue SarcomaPhase 2

Active, not recruiting

Competition

Competitive Landscape

947 competitors in Melanoma

#DrugCompanyPhaseTrials

Taxol

Teva

Phase 3

13 2

Fabhalta

Regeneron

Phase 3

3 3

Spartalizumab

Novartis

Phase 3

2 4

Deltavit

HHyundai Pharmaceutical Co., LTD.

Phase 3

—5

Zelboraf

CConrado Roberto Hoffmann Filho

Preclinical

39 6

isolated limb perfusion

MMemorial Sloan Kettering Cancer Center

Phase 3

2 7

Intron a

Merck & Co.

Preclinical

4 8

Opdualag

Bristol-Myers Squibb

Preclinical

3 9

Naporafenib

EErasca, Inc.

Phase 3

1 10

PEG-Intron

Merck & Co.

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Soft Tissue Sarcoma2 trials

Isolated Limb Infusion of Chemotherapy in Treating Patients With Melanoma or Soft Tissue Sarcoma of the Arm or Leg That Cannot Be Removed By Surgery

Completed·MMemorial Sloan Kettering Cancer Center·Phase 2·NCT00004250·35 enrolled

Combination Chemotherapy in Treating Patients With Soft Tissue Sarcoma

Completed·UUniversity of Miami·Phase 2·NCT00002492

Melanoma2 trials

Isolated Limb Perfusion With Melphalan in Treating Patients With Stage IIIB-IV Melanoma or Sarcoma

Withdrawn·—·N/A·NCT02507076

Melphalan With or Without Tumor Necrosis Factor in Treating Patients With Locally Advanced Melanoma of the Arm or Leg

Completed·NNational Cancer Institute (NCI)·Phase 3·NCT00003789·216 enrolled

Sources

References

[1]
ClinicalTrials.gov — 4 trial records for isolated limb perfusion. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — isolated limb perfusion compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for isolated limb perfusion. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Memorial Sloan Kettering Cancer Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: MMemorial Sloan Kettering Cancer Center

isolated limb perfusion

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Soft Tissue Sarcoma2 trials

Melanoma2 trials

References

Drug Info

Quick Facts

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