Levonorgestrel IUS

ApprovedSmall molecule

Bayer

Levonorgestrel IUS is one of 161 small molecule programs targeting Contraception. It is currently in Approved.

Indications

Total Trials

Active Trials

160

Competitors

Pipeline

Status by Indication[3][1]

Indication

ContraceptionActive, not recruiting

AbortionActive, not recruiting

DysmenorrheaActive, not recruiting

Uterine FibroidActive, not recruiting

MenorrhagiaActive, not recruiting

EpilepsyActive, not recruiting

ContraceptionPreclinical

Active, not recruiting

AbortionPreclinical

Active, not recruiting

DysmenorrheaPreclinical

Active, not recruiting

Uterine FibroidApproved

Active, not recruiting

MenorrhagiaPhase 3

Active, not recruiting

EpilepsyApproved

Active, not recruiting

Competition

Competitive Landscape

221 competitors in Epilepsy

#DrugCompanyPhaseTrials

Epidiolex

Jazz Pharmaceuticals

Phase 3

9 2

Dayvigo

Eisai

Phase 3

1 3

Depacon

AbbVie

Phase 3

1 4

Levonorgestrel IUS

Bayer

Approved

1 5

Fintepla

IImmedica Pharma AB

Phase 3

4 6

Actemra

Roche

Phase 3

—7

Deltavit

HHyundai Pharmaceutical Co., LTD.

Phase 3

3 8

Narcan

SScienture

Phase 3

1 9

GWP42003-P

Jazz Pharmaceuticals

Phase 3

1 10

Immunoglobulin

Sanofi

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Menorrhagia2 trials

Study in Women With Idiopathic Menorrhagia to Determine the Reduction in Menstrual Blood Loss (MBL) After Treatment With the Levonorgestrel-releasing Intrauterine System (IUS)

Completed· Bayer logo

Bayer·Phase 3·NCT00360490·165 enrolled

Mirena in Idiopathic Menorrhagia

Completed· Bayer logo

Bayer··NCT00868153·1,125 enrolled

Epilepsy1 trial

Women With Epilepsy: a Pilot Study of PK and PD Anti-epileptic Drug Effects in Levonorgestrel Intrauterine System Users

Completed·—·Phase 4·NCT02362373·20 enrolled

OSA1 trial

Impact of Contraceptives on Cervico-Vaginal Mucosa

Completed·—·Phase 4·NCT04814927·112 enrolled

Uterine Fibroid1 trial

Treatment of Heavy Menstrual Bleeding in Women With Uterine Fibroids

Completed·—·Phase 4·NCT03317795·18 enrolled

Dysmenorrhea1 trial

Prospective, Non-interventional, Multi-center Safety Study of Mirena for Heavy Menstrual Bleeding and Dysmenorrhea

Completed· Bayer logo

Bayer··NCT02475356·601 enrolled

6 more indications

Phase II1 trial

GA Levonorgestrel Intrauterine Contraceptive System (LCS) Phase III Study China

Completed· Bayer logo

Bayer·Phase 3·NCT00884260·918 enrolled

Trial1 trial

Mirena Extension Trial

Completed· Bayer logo

Bayer·Phase 3·NCT02985541·364 enrolled

Contraception1 trial

Acceptability of Long-term Progestin-only Contraception in Europe

Completed· Bayer logo

Bayer··NCT00931827·436 enrolled

Abortion1 trial

Bleeding Pattern Difference Between Levonorgestrel Intrauterine System (LNG-IUS) and Copper Intrauterine Devices (IUDs) Immediately Inserted After Abortion

Completed· Bayer logo

Bayer··NCT01958684·512 enrolled

ART1 trial

Early Postpartum Intrauterine Device (IUD) Placement

Terminated·OOregon Health and Science University·Phase 4·NCT01594476·201 enrolled

Unspecified2 trials

Dose-finding Study for the Ultralow-dose Levonorgestrel Intrauterine Contraceptive System (LCS)

Completed· Bayer logo

Bayer·Phase 2·NCT00185380·742 enrolled

Mirena Post-marketing Surveillance in Japan

Completed· Bayer logo

Bayer··NCT01414140·567 enrolled

Sources

References

[1]
ClinicalTrials.gov — 13 trial records for Levonorgestrel IUS. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Levonorgestrel IUS compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Levonorgestrel IUS. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Bayer company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: Bayer

Levonorgestrel IUS

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Menorrhagia2 trials

Epilepsy1 trial

OSA1 trial

Uterine Fibroid1 trial

Dysmenorrhea1 trial

Phase II1 trial

Trial1 trial

Contraception1 trial

Abortion1 trial

ART1 trial

Unspecified2 trials

References

Drug Info

Quick Facts

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