Levothyroxine Sodium
ApprovedSmall molecule
Mylan Pharmaceuticals IncLevothyroxine Sodium is a small molecule that works as a Thyroid Hormone Receptor Agonist.[2] It is being used across 7 indications, with its most advanced program in Approved.[1]
Levothyroxine Sodium is one of 160 small molecule programs targeting Hypothyroidism. It is currently in Approved.
7
Indications
19
Total Trials
4
Active Trials
159
Competitors
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
210 competitors in Thyroid Cancer
#DrugCompanyPhaseTrials
1Nexavar
BayerPhase 3
Levothyroxine Sodium
Mylan Pharmaceuticals IncApproved
Koselugo
AstraZenecaPhase 3
Glucophage
EMD SeronoPhase 3
Afinitor
NovartisPhase 2
Votrient
NovartisPhase 2
Yervoy
Bristol-Myers SquibbPhase 2
Stivarga
BayerPhase 2
Mektovi
PfizerPhase 2
Cotellic
RochePhase 2
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Hypothyroidism4 trials
Thyroid Replacement Therapy in Patients With Subclinical Hypothyroidism
Unknown status·—·Phase 4·NCT04953195·30 enrolled
Thyroid3 trials
Individual Dosing of Levothyroxine After Thyroidectomy
Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·N/A·NCT05240911·202 enrolled
Randomized Controlled Trial1 trial
6 more indications
Non-Alcoholic Fatty Liver Disease1 trial
Levothyroxine for Non-Alcoholic Fatty Liver Disease (NAFLD)
Terminated·—·Phase 2·NCT03281083·29 enrolled
Treatment1 trial
Low Dose Euthyrox in Treatments of Paraquat Intoxication.
Unknown status·SSecond Affiliated Hospital, School of Medicine, Zhejiang University·Phase 4·NCT04132622·80 enrolled
Dialysis Patients1 trial
Congenital Hypothyroidism1 trial
Unspecified4 trials
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Levothyroxine Sodium. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Thyroid Hormone Receptor Agonist[2]
- Modality
- Small molecule[2]
- Highest Phase
- Approved[1]
- Company