magnesium oxide

ApprovedSmall molecule

VVirginia Commonwealth University

magnesium oxide is one of 156 small molecule programs targeting Constipation. It is currently in Approved.

Indications

Total Trials

Active Trials

155

Competitors

Pipeline

Status by Indication[3][1]

Indication

Brain InjuryActive, not recruiting

Breast CancerActive, not recruiting

Heart FailureActive, not recruiting

Atrial FibrillationActive, not recruiting

Hot FlashesActive, not recruiting

Brain InjuryPhase 1

Active, not recruiting

Breast CancerPhase 2

Active, not recruiting

Heart FailurePhase 3

Active, not recruiting

Atrial FibrillationApproved

Active, not recruiting

Hot FlashesPhase 2

Active, not recruiting

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

magnesium oxide

VVirginia Commonwealth University

Approved

1 2

Tykerb

GSK

Preclinical

80 3

Avastin

BBio-Thera Solutions

Preclinical

153 4

Nolvadex

SSan Diego Pacific Oncology & Hematology Associates

Preclinical

78 5

Prolia

Amgen

Preclinical

14 6

Adenocard

Astellas

Preclinical

1 7

Voltaren

Novartis

Preclinical

1 8

Blenoxane

Bristol-Myers Squibb

Preclinical

1 9

Lupron

EEastern Cooperative Oncology Group

Preclinical

5 10

Sporanox

SSebela Pharmaceuticals Development LLC

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q2 2027

Post-ApprovalRecruiting

Atrial Fibrillation

NCT07173855

Clinical

Trials by Indication[1]

Atrial Fibrillation1 trial

Effect of Protocolized Magnesium Replacement on Mortality and Atrial Fibrillation in Critically Ill Patients

Recruiting·SScarborough General Hospital·Phase 4·NCT07173855·3,253 enrolled

Heart Failure1 trial

The Impact of Magnesium on Exercise Tolerance, Quality of Life and Clinical Outcomes in Chronic Heart Failure Patients

Unknown status·SSheba Medical Center·Phase 3·NCT03840226·320 enrolled

Brain Injury1 trial

A Cohort Study Evaluating the Efficacy of PO Magnesium in the Treatment of Acute Traumatic Brain Injury in Adolescents

Completed·CCorewell Health South·Phase 1·NCT03475693·17 enrolled

Breast Cancer1 trial

Magnesium Oxide in Treating Postmenopausal Women With Hot Flashes and a History of Breast Cancer

Completed·AAlliance for Clinical Trials in Oncology·Phase 2·NCT01439945·289 enrolled

Constipation1 trial

The Effect of Probiotics on Constipation, and Intestinal Microflora in Children With Functional Constipation

Completed·—·Phase 4·NCT03054805·153 enrolled

3 more indications

Pregnancy1 trial

Effect of Magnesium Supplement in Early Pregnancy After ICSI

Unknown status·—·Phase 3·NCT03398031·180 enrolled

Hot flashes1 trial

Magnesium Oxide in Treating Hot Flashes in Menopausal Women With Cancer

Completed·VVirginia Commonwealth University·Phase 2·NCT01008904·31 enrolled

Treatment1 trial

Magnesium Supplements In The Treatment Of Pseudoxanthoma Elasticum (PXE)

Completed·MMark Lebwohl·Phase 2·NCT01525875·44 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for magnesium oxide. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — magnesium oxide compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for magnesium oxide. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Virginia Commonwealth University company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: VVirginia Commonwealth University

magnesium oxide

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q2 2027

Trials by Indication[1]

Atrial Fibrillation1 trial

Heart Failure1 trial

Brain Injury1 trial

Breast Cancer1 trial

Constipation1 trial

Pregnancy1 trial

Hot flashes1 trial

Treatment1 trial

References

Drug Info

Quick Facts

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