Maintenance chemotherapy

Phase 2Small molecule

UUniversity of Texas Southwestern Medical Center

Maintenance chemotherapy is one of 107 small molecule programs targeting Metastatic Colorectal Cancer. It is currently in Phase 2.

Indications

Total Trials

Active Trials

106

Competitors

Pipeline

Status by Indication[3][1]

Indication

Metastatic Colorectal CancerActive, not recruiting

Non-Small Cell Lung CancerActive, not recruiting

MedulloblastomaActive, not recruiting

Metastatic Colorectal CancerPhase 2

Active, not recruiting

Non-Small Cell Lung CancerPhase 2

Active, not recruiting

MedulloblastomaPhase 2/Phase 3

Active, not recruiting

Competition

Competitive Landscape

1639 competitors in Non-Small Cell Lung Cancer

#DrugCompanyPhaseTrials

Yervoy

Bristol-Myers Squibb

Preclinical

31 2

Lenvima

Eisai

Preclinical

6 3

Imjudo

AstraZeneca

Preclinical

5 4

Vizimpro

Pfizer

Preclinical

4 5

Gilotrif

Boehringer Ingelheim

Preclinical

12 6

Maintenance chemotherapy

UUniversity of Texas Southwestern Medical Center

Phase 2

1 7

Ofev

Boehringer Ingelheim

Preclinical

7 8

Immunotherapy

Bristol-Myers Squibb

Preclinical

12 9

Remeron

OOrganon and Co

Preclinical

1 10

Tyrosine Kinase Inhibitor

Pfizer

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 2/3Active, not recruiting

Medulloblastoma

NCT02066220

Clinical

Trials by Indication[1]

Metastatic Colorectal Cancer2 trials

Maintenance Therapy With 5-FU/FA Plus Panitumumab vs. 5-FU/FA Alone After Prior Induction and Re-induction After Progress for 1st-line Treatment of Metastatic Colorectal Cancer

Completed·AAIO-Studien-gGmbH·Phase 2·NCT01991873·387 enrolled

Consolidative Radiotherapy Plus Maintenance Chemotherapy for Metastatic Colorectal Cancer

Unknown status·UUnion Hospital, Tongji Medical College, Huazhong University of Science and Technology·Phase 2·NCT03142282·200 enrolled

Medulloblastoma2 trials

International Society of Paediatric Oncology (SIOP) PNET 5 Medulloblastoma

Active, not recruiting·UUniversitätsklinikum Hamburg-Eppendorf·Phase 2/3·NCT02066220·360 enrolled

Multicenter Pilot-study for the Therapy of Medulloblastoma of Adults

Completed·UUniversity of Regensburg·Phase 1/2·NCT01614132·33 enrolled

Non-Small Cell Lung Cancer1 trial

Maintenance Chemotherapy Versus Consolidative Stereotactic Body Radiation Therapy (SBRT) Plus Maintenance Chemotherapy for Stage IV Non-Small Cell Lung Cancer (NSCLC): A Randomized Phase II Trial

Completed·UUniversity of Texas Southwestern Medical Center·Phase 2·NCT02045446·29 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Maintenance chemotherapy. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Maintenance chemotherapy compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Maintenance chemotherapy. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — University of Texas Southwestern Medical Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: UUniversity of Texas Southwestern Medical Center

Maintenance chemotherapy

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Trials by Indication[1]

Metastatic Colorectal Cancer2 trials

Medulloblastoma2 trials

Non-Small Cell Lung Cancer1 trial

References

Drug Info

Quick Facts

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