Oncovin
(Vincristine Sulfate)Phase 3Small molecule
Vincristine sulfate is a chemotherapy drug used to treat various types of cancer, including leukemia and lymphoma, by stopping cancer cells from dividing and growing.[1] Oncovin is currently being investigated across 71 indications[3], with its most advanced program in Phase 3.[1]
Oncovin is one of 979 small molecule programs targeting Glioma. It is currently in Phase 3.
71
Indications
442
Total Trials
26
Active Trials
978
Competitors
Pipeline
Status by Indication[3][1]
Indication
Showing 10 of 70 indications
Competition
Competitive Landscape
1774 competitors in Lymphoma
#DrugCompanyPhaseTrials
1Oncovin
EEastern Cooperative Oncology Group
Phase 3
Blenoxane
SSequus Pharmaceuticals
Preclinical
Zofran
NovartisPreclinical
Norvir
AbbViePreclinical
Wellcovorin
GGlaxo Dba Glaxosmithkline
Preclinical
PEG-Intron
Merck & Co.Preclinical
Decadron
QQuince Therapeutics S.p.A.
Preclinical
Solu-Medrol
MMassachusetts Eye and Ear Infirmary
Preclinical
Rhg-CSF
CCSPC Baike (Shandong) Biopharmaceutical Co., Ltd.
Preclinical
Stem Cells
KKang Stem Biotech Co., Ltd.
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Lymphoma49 trials
Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma
Active, not recruiting·—·Phase 2·NCT03749018·30 enrolled
Show 46 more trials
Gene Therapy and Combination Chemotherapy in Treating Patients With AIDS-Related Non-Hodgkin Lymphoma
Active, not recruiting·—·Phase 1·NCT02337985·10 enrolled
Combination Chemotherapy With or Without Rituximab in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
Completed·EEuropean Organisation for Research and Treatment of Cancer - EORTC·Phase 3·NCT00004179·475 enrolled
Fludeoxyglucose F 18 Positron Emission Tomography in Predicting Risk of Relapse in Patients With Non-Hodgkin's Lymphoma Who Are Undergoing Combination Chemotherapy With or Without Autologous Stem Cell or Bone Marrow Transplant
Completed·SSidney Kimmel Comprehensive Cancer Center at Johns Hopkins·Phase 2·NCT00238368·59 enrolled
Molecular Risk Assessment in Planning Treatment for Patients With Non-Hodgkin's Lymphoma
Completed·—·Phase 2·NCT00055640·9 enrolled
Vincristine Sulfate Liposome Injection (Marqibo®), Bendamustine and Rituximab-Phase I Trial in Indolent B-cell Lymphoma
Completed·—·Phase 1·NCT02257242·11 enrolled
Acute Lymphoblastic Leukemia43 trials
Show 40 more trials
Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia
Recruiting·—·Phase 1·NCT05157971·24 enrolled
Asparaginase Erwinia Chrysanthemi With Chemotherapy for the Treatment of High-Risk Adults With Newly Diagnosed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Recruiting·—·Phase 2·NCT06918431·53 enrolled
Imatinib Mesylate and Combination Chemotherapy With or Without a Donor Stem Cell Transplant in Treating Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Completed·—·Phase 2·NCT00618501·50 enrolled
05-001: Treatment of Acute Lymphoblastic Leukemia in Children
Completed·—·Phase 3·NCT00400946·800 enrolled
Neuroblastoma14 trials
Show 11 more trials
Combination Chemotherapy or Observation Following Surgery in Treating Infants With Neuroblastoma
Completed·—·Phase 2·NCT00002803·44 enrolled
Leukemia10 trials
Show 7 more trials
Rhabdomyosarcoma6 trials
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50 more indications
Primitive Neuroectodermal Tumor5 trials
Medulloblastoma5 trials
Diffuse Large B-Cell Lymphoma5 trials
Carfilzomib, Rituximab, and Combination Chemotherapy in Treating Patients With Diffuse Large B-Cell Lymphoma
Completed·—·Phase 1/2·NCT02073097·48 enrolled
Multiple Myeloma4 trials
Retinoblastoma4 trials
Glioma3 trials
Hodgkin's Disease3 trials
Chemotherapy2 trials
Anaplastic Large Cell Lymphoma2 trials
Mantle Cell Lymphoma2 trials
Bone Marrow Transplantation2 trials
Kaposi's sarcoma2 trials
A Study of Chemotherapy Plus Azidothymidine in the Treatment of Kaposi's Sarcoma in Patients With AIDS
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00000987·36 enrolled
Radiation Therapy2 trials
Kidney Cancer1 trial
Soft Tissue Sarcoma1 trial
Ewing's Sarcoma1 trial
Ewing sarcoma1 trial
Refractory Solid Tumors1 trial
T-cell non-Hodgkin lymphoma1 trial
Liver Cancer1 trial
Precursor B-Cell Acute Lymphoblastic Leukemia1 trial
Chronic Lymphocytic Leukemia1 trial
Central Nervous System1 trial
Ependymoma1 trial
Newly Diagnosed1 trial
Adult T-Cell Leukemia/lymphoma1 trial
Colon Cancer1 trial
Germ Cell Tumor1 trial
Hyperglycemia1 trial
Immunosuppression1 trial
Induction Therapy1 trial
Small Cell Lung Cancer1 trial
Colorectal Cancer1 trial
Adjuvant Chemotherapy1 trial
HIV infection1 trial
Stem Cell Transplantation1 trial
Lymphoblastic Lymphoma1 trial
Anaplastic Oligodendroglioma1 trial
T-cell acute lymphoblastic leukemia1 trial
Vomiting1 trial
Cervical Cancer1 trial
Neuroectodermal Tumors1 trial
Immunotherapy1 trial
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Vincristine Sulfate. EMBL-EBI & Wellcome Sanger Institute.
- [4]
Details