MgSO4

ApprovedSmall molecule

SServices Institute of Medical Sciences, Pakistan

MgSO4 is one of 131 small molecule programs targeting Encephalopathy. It is currently in Approved.

Indications

Total Trials

Active Trials

130

Competitors

Pipeline

Status by Indication[3][1]

Indication

EncephalopathyActive, not recruiting

HysterectomyActive, not recruiting

PreeclampsiaActive, not recruiting

Cesarean SectionActive, not recruiting

EncephalopathyPhase 2

Active, not recruiting

HysterectomyApproved

Active, not recruiting

PreeclampsiaPreclinical

Active, not recruiting

Cesarean SectionPhase 2/Phase 3

Active, not recruiting

Competition

Competitive Landscape

230 competitors in Cesarean Section

#DrugCompanyPhaseTrials

MgSO4

SServices Institute of Medical Sciences, Pakistan

Approved

1 2

Pitocin

RRetrophin

Preclinical

16 3

Dynastat

Pfizer

Preclinical

1 4

Ancef

BBaxter Healthcare Corporation

Preclinical

3 5

Nubain

AAultman Health Foundation

Preclinical

3 6

Intrathecal Morphine

Pacira Pharmaceuticals, Inc

Preclinical

5 7

Sufenta

LLeaf Vertical Inc.

Preclinical

1 8

Imdur

OOmnivium

Preclinical

1 9

Bactroban

PPadagis LLC

Preclinical

1 10

Imitrex

GGlaxo Dba Glaxosmithkline

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

N/ANot yet recruiting

Magnesium Sulfate

NCT07199595

Clinical

Trials by Indication[1]

Magnesium Sulfate8 trials

Dexmedetomidine Versus Magnesium Sulfate Infusion in Craniotomy

Not yet recruiting·—·N/A·NCT07199595·60 enrolled

Effect of Administering Intravenous Magnesium Sulfate on Fetal Cardiotocography and Neonatal Outcome in Preeclamptic Patients

Unknown status·—·Phase 4·NCT03237000·100 enrolled

Adding Magnesium Sulfate to Bupivacaine for Ilioinguinal and Iliohypogastric Nerve Block

Completed·—·Phase 2·NCT05158647·90 enrolled

Show 5 more trials

Comparison Between Botox and Magnesium Sulfate Effect in Treatment of Myofascial Pain Trigger Points Within the Masseter Muscle

Not yet recruiting·MMisr University for Science and Technology·Phase 2/3·NCT06676475·60 enrolled

Evaluation of the Role of Low Dose Magnesium Sulfate in Anesthesia for Toxic Goiter Resection

Completed·FFayoum University Hospital·Phase 4·NCT04632524·60 enrolled

Magnesium Sulfate for Fetal Neuroprotection

Unknown status·—·N/A·NCT04401852·200 enrolled

The Effect of Intrathecal Magnesium Sulfate on Shivering

Completed·YYuzuncu Yil University·N/A·NCT05427149·120 enrolled

Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial

Withdrawn·—·Phase 2/3·NCT00293735

Preeclampsia3 trials

The Effect of Loading Dose of Magnesium Sulfate on Uterine, Umbilical, and Fetal Middle Cerebral Arteries Doppler, Biophysical Profile, CTG, Maternal Vital Signs in Women With Severe Preeclampsia

Unknown status·—·N/A·NCT03891498·100 enrolled

Risk Analysis of Intensive Care Mangement on Maternal and Fetal Outcome of Severe Preeclampsia and Eclampsia

Completed·—··NCT03412552·1,238 enrolled

New Magnesium Sulphate Protocol for Pre-eclampsia

Completed·—·Phase 3·NCT01846156·240 enrolled

Efficacy and Safety1 trial

Efficacy and Safety of MgSO4 as Tocolytics Compared to Ritodrine in Preterm Labor

Completed·SSeoul National University Hospital·N/A·NCT02538718·34 enrolled

Intravenous1 trial

Effects Of Additional MgSO4 30 Mg/KgBW Intravenous and Ketorolac

Completed·IIndonesia University·Phase 4·NCT05609955·48 enrolled

Cesarean Section1 trial

Shivering Prevention During Cesarean Section by Intrathecal Injection of Magnesium Sulfate

Completed·—·Phase 2/3·NCT03008850·84 enrolled

4 more indications

Abdominal Surgery1 trial

Effect of Magnesium Sulphate Pretreatment in Pediatric Abdominal Surgery

Recruiting·—·Phase 2/3·NCT05736744·58 enrolled

Hysterectomy1 trial

Comparative Study Between the Analgesic Effect of Dexmedetomidine and Magnesium Sulfate As Adjuvant to Bupivacaine Using Ultrasound-Guided Transversus Abdominis Plane Block in Abdominal Hysterectomy : a Randomized Double-blinded Study

Not yet recruiting·—·Phase 4·NCT06720337·64 enrolled

Encephalopathy1 trial

Beneficial Effect of Intravenous Magnesium Sulphate in Term Neonates With Hypoxic Ischemic Encephalopathy(HIE)

Completed·SServices Institute of Medical Sciences, Pakistan·Phase 2·NCT04705142·200 enrolled

Hemodynamic1 trial

Magnesium Sulphate for Attenuation of Hemodynamic Pressor Response After Myfield's Clamp Application

Completed·EEl-Sahel Teaching Hospital·Phase 4·NCT03318471·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 18 trial records for MgSO4. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — MgSO4 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for MgSO4. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Services Institute of Medical Sciences, Pakistan company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: SServices Institute of Medical Sciences, Pakistan

MgSO4

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Trials by Indication[1]

Magnesium Sulfate8 trials

Preeclampsia3 trials

Efficacy and Safety1 trial

Intravenous1 trial

Cesarean Section1 trial

Abdominal Surgery1 trial

Hysterectomy1 trial

Encephalopathy1 trial

Hemodynamic1 trial

References

Drug Info

Quick Facts

Related News