NNC0194-0499

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

13 competitors in Diabetes Mellitus, Type 1

#DrugCompanyPhaseTrials

1

Glucophage

EMD Serono

Approved

12

Olumiant

Eli Lilly

Phase 3

23

Opzelura

Pfizer

Phase 2

14

Insulin Icodec

Novo Nordisk

Phase 3

35

Bacillus Calmette-Guérin

Bristol-Myers Squibb

Phase 2

16

Ozempic

Novo Nordisk

Phase 1

17

Mounjaro

Eli Lilly

Phase 1

18

Tylenol

KKenvue Brands

Phase 1

19

Oraverse

LLife Extension Foundation Inc.

Preclinical

110

NNC0194-0499

Novo Nordisk

Phase 1

1

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Single Dose2 trials

A Research Study Looking at How a Single Dose of the Study Medicine NNC0194-0499 Behaves in Participants With Reduced Liver Function Compared to Participants With Normal Liver Function

Completed·Novo Nordisk·Phase 1·NCT05917938·33 enrolled

A Research Study Looking at How a Single Dose of the Medicine NNC0194-0499 Behaves in Chinese Men

Completed·Novo Nordisk·Phase 1·NCT05742919·24 enrolled

Overweight2 trials

A Research Study Looking at a New Study Medicine (NNC0194-0499) for Weight Control in People With Overweight or Obesity

Completed·Novo Nordisk·Phase 1·NCT03479892·57 enrolled

First Human Dose Trial Investigating Safety, Tolerability and Pharmacokinetics of NNC0194-0499 in Male Subjects With Overweight or Obesity

Completed·Novo Nordisk·Phase 1·NCT03015207·56 enrolled

Liver Disease1 trial

Effects of NNC0194-0499, Cagrilintide, and Semaglutide Alone or in Combinations on Liver Damage and Alcohol Use in People With Alcohol-related Liver Disease

Completed·Novo Nordisk·Phase 2·NCT06409130·270 enrolled

Children1 trial

A Research Study Looking at How the Compound NNC0194-0499 Works With Birth Control Pills in Women Not Able to Bear Children.

Completed·Novo Nordisk·Phase 1·NCT06188026·34 enrolled

Function1 trial

A Research Study Looking Into Blood and Urine Levels of the Medicine NNC0194-0499 in the Body and How Well it is Tolerated in Participants With Reduced Kidney Function and Normal Kidney Function

Completed·Novo Nordisk·Phase 1·NCT05727644·42 enrolled

3 more indications

Semaglutide1 trial

A Research Study Comparing Blood Levels of Medicines NNC0194-0499 and Semaglutide Administered as a Combination Formulation Versus Two Separate Formulations

Completed·Novo Nordisk·Phase 1·NCT05766709·53 enrolled

Diabetes Mellitus, Type 11 trial

A Study to Investigate Efficacy and Safety of NNC0194-0499 Versus Placebo, Both Administered Alone or in Combination With Semaglutide in People With Type 1 Diabetes

Active, not recruiting·Novo Nordisk·Phase 1·NCT07087795·96 enrolled

Unspecified1 trial

A Research Study Looking at How the Medicine NNC0194-0499 Behaves in Japanese and Non-Asian Men

Completed·Novo Nordisk·Phase 1·NCT04722653·42 enrolled

Details

Drug Info

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