Oxycodone/Acetaminophen

PreclinicalSmall molecule

Oxycodone/Acetaminophen is one of 8 small molecule programs targeting Alpha-1 Antitrypsin Deficiency. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Alpha-1 Antitrypsin DeficiencyActive, not recruiting

Alpha-1 Antitrypsin DeficiencyPreclinical

Active, not recruiting

Competition

Competitive Landscape

11 competitors in Alpha-1 Antitrypsin Deficiency

#DrugCompanyPhaseTrials

Zofran

Novartis

Preclinical

1 2

SAR447537

Sanofi

Phase 2

1 3

Duragesic

CCephalon

Preclinical

1 4

Xylocaine

MMEDRx USA, Inc.

Preclinical

1 5

Tylenol

KKenvue Brands

Preclinical

1 6

Ativan

BBausch Health Americas, Inc.

Preclinical

1 7

Versed

CConrado Roberto Hoffmann Filho

Preclinical

1 8

Oxycodone/Acetaminophen

MMontefiore Medical Center

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Injury1 trial

Safety and Efficacy Study of Fentanyl Buccal Tablet Use in the Emergency Department for Isolated Extremity Injury

Completed·UUniversity of Oklahoma·Phase 3·NCT01270659·60 enrolled

Mucositis1 trial

Gabapentin Compared to Standard of Care in Preventing Mucositis in Patients With Stage III-IV Head and Neck Cancer Undergoing Primary or Adjuvant Chemoradiation Therapy

Completed·VVanderbilt-Ingram Cancer Center·Phase 3·NCT02480114·79 enrolled

Recurrent1 trial

A Study Comparing Recurrent Use of MSIR, Percocet, and Vicodin at Discharge From the ED

Withdrawn·AAntonios Likourezos·Phase 4·NCT03529331

Analgesic1 trial

Comparative Efficacy of 4 Oral Analgesics

Completed·MMontefiore Medical Center·Phase 4·NCT02455518·416 enrolled

Randomized1 trial

Randomized Trial of Two Analgesics in Elderly ED Patients

Withdrawn·—·Phase 4·NCT02703610

1 more indication

Alpha-1 Antitrypsin Deficiency1 trial

Liver Fibrosis in Alpha-1 Antitrypsin Deficiency (Liver AATD)

Completed·UUniversity of Florida··NCT01810458·109 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Oxycodone/Acetaminophen. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Oxycodone/Acetaminophen compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Oxycodone/Acetaminophen. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Montefiore Medical Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: MMontefiore Medical Center

Oxycodone/Acetaminophen

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Injury1 trial

Mucositis1 trial

Recurrent1 trial

Analgesic1 trial

Randomized1 trial

Alpha-1 Antitrypsin Deficiency1 trial

References

Drug Info

Quick Facts

Related News