Plenvu

Phase 3Small molecule

JJohannes Gutenberg University Mainz

Plenvu is one of 12 small molecule programs targeting Bowel Preparation. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Bowel PreparationCompleted

ColonoscopyRecruiting

Bowel PreparationPreclinical

Completed

ColonoscopyPhase 3

Recruiting

Competition

Competitive Landscape

15 competitors in Bowel Preparation

#DrugCompanyPhaseTrials

Resotran

Takeda

Phase 3

3 2

Dulcolax

Boehringer Ingelheim

Phase 3

4 3

Plenvu

JJohannes Gutenberg University Mainz

Phase 3

2 4

Mechanical Bowel Preparation

HHelsinki University Central Hospital

Phase 3

1 5

Reglan

IIstituto Clinico Humanitas

Preclinical

2 6

Senna

MMedtronic - MITG

Preclinical

3 7

PEG-ELS

Ferring

Preclinical

2 8

CLENPIQ

Ferring

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2027

Phase 3Recruiting

Colonoscopy

NCT07218523

Clinical

Trials by Indication[1]

Colonoscopy3 trials

Comparison of Two Preparations for the Study of the Colon Through Colonoscopy

Completed·UUnidade Local de Saúde do Alto Ave, EPE··NCT04497935·613 enrolled

A Study to Investigate Bowel Cleansing With PLENVU® Compared to Sodium Picosulfate in Participants Aged 1 to < 18 Years of Age in Preparation for Colonoscopy

Recruiting·NNorgine·Phase 3·NCT07218523·212 enrolled

A Trial to Compare Efficacy and Tolerability of Plenvu® and Picoprep® as Cleansing Agents Before Colonoscopy

Recruiting·—·Phase 4·NCT05436054·400 enrolled

Bowel Preparation2 trials

Effect of Low-volume (1L) vs Intermediate-volume (2L) Bowel Preparation on Cost-effectiveness and Quality of Life

Completed·RRadboud University Medical Center·N/A·NCT05242562·509 enrolled

QR Code for Endoscopic Bowel Preparation

Unknown status·JJohannes Gutenberg University Mainz··NCT04456231·404 enrolled

Colorectal Cancer1 trial

Two Low Volume Regimens for Colorectal Cancer Screening Colonoscopy

Completed·HHospital Clinic of Barcelona·Phase 4·NCT04297423·1,002 enrolled

Effectiveness1 trial

Effectiveness of PLENVU in the General Screening Population and Patients With IBD

Unknown status·JJohannes Gutenberg University Mainz··NCT04457934·290 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Plenvu. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Plenvu compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Plenvu. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Johannes Gutenberg University Mainz company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: JJohannes Gutenberg University Mainz

Plenvu

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2027

Trials by Indication[1]

Colonoscopy3 trials

Bowel Preparation2 trials

Colorectal Cancer1 trial

Effectiveness1 trial

References

Drug Info

Quick Facts

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