Polyethylene Glycols

PreclinicalSmall molecule

JJinnah Postgraduate Medical Centre

Polyethylene Glycols is one of 55 small molecule programs targeting Constipation. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Fecal IncontinenceActive, not recruiting

Inflammatory Bowel DiseaseActive, not recruiting

Fecal IncontinencePreclinical

Active, not recruiting

Inflammatory Bowel DiseasePreclinical

Active, not recruiting

Competition

Competitive Landscape

62 competitors in Inflammatory Bowel Disease

#DrugCompanyPhaseTrials

Remicade

Johnson & Johnson

Approved

17 2

Skyrizi

AbbVie

Approved

3 3

Dificlir

Merck & Co.

Approved

1 4

Humira

RRanbaxy Laboratories Limited

Approved

7 5

Calciferol

Mounjaro

Elavil

Vancocin

HHikma Pharmaceuticals LLC

Approved

1 9

Aplenzin

GGlaxo Dba Glaxosmithkline

Approved

1 10

Spravato

WWim Janssens

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Encephalopathy2 trials

Polyethylene Glycol Versus Lactulose on Hepatic Encephalopathy in Patients With Cirrhosis;(PEGHE Trial)

Unknown status·—·Phase 4·NCT04436601·102 enrolled

Efficacy of L-Ornithine L-Aspartate and Polyethylene Glycol in Cirrhotic Patients With Overt Hepatic Encephalopathy

Unknown status·JJinnah Postgraduate Medical Centre·Phase 4·NCT05920213·360 enrolled

Fecal Incontinence1 trial

Effect of MiniGo As Add-on to Oral Laxatives for Children with Constipation and Fecal Incontinence

Completed·UUniversity of Aarhus·N/A·NCT05570318·50 enrolled

Paralysis1 trial

Naloxegol to Prevent Lower Gastrointestinal Paralysis in Critically Ill Adults Administered Opioids

Terminated·TTufts Medical Center·Phase 4·NCT02977286·12 enrolled

Volume1 trial

Comparison of Low Volume PEG-Asc and Lower Volume PEG-Asc With Bisacodyl

Completed·KKorea University Anam Hospital·Phase 3·NCT02980562·200 enrolled

Colonoscopy1 trial

Polyethylene Glycol Versus Low Volume Solutions Prior to Colonoscopy

Completed·TTomas Bata Hospital, Czech Republic·Phase 4·NCT02956057·1,044 enrolled

3 more indications

Inflammatory Bowel Disease1 trial

A Prospective Study of the Effect of Modified Colonoscopy Bowel Preparation Program on Intestinal Cleaning, Examination and Disease in Patients With Inflammatory Bowel Disease

Unknown status·PPeking Union Medical College Hospital·N/A·NCT05485103·144 enrolled

Constipation1 trial

Physical Therapy for Functional Constipation in Children

Completed·—·N/A·NCT06207721·400 enrolled

Other1 trial

Conversion of Seddon III Nerve Injury to Seddon I/II Nerve Injury

Terminated·WWellSpan Health·Phase 1·NCT03236064·4 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for Polyethylene Glycols. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Polyethylene Glycols compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Polyethylene Glycols. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Jinnah Postgraduate Medical Centre company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: JJinnah Postgraduate Medical Centre

Polyethylene Glycols

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Encephalopathy2 trials

Fecal Incontinence1 trial

Paralysis1 trial

Volume1 trial

Colonoscopy1 trial

Inflammatory Bowel Disease1 trial

Constipation1 trial

Other1 trial

References

Drug Info

Quick Facts

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