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PrEP

PreclinicalSmall molecule

UUniversity of Washington

PrEP is one of 43 small molecule programs targeting Female. It is currently in Preclinical.

3

Indications

18

Total Trials

1

Active Trials

42

Competitors

Pipeline

Status by Indication[3][1]

Indication

FemaleCompleted

ProphylaxisCompleted

TelemedicineCompleted

FemalePreclinical

Completed

ProphylaxisPreclinical

Completed

TelemedicinePreclinical

Completed

Competition

Competitive Landscape

27 competitors in Prophylaxis

#DrugCompanyPhaseTrials

Eliquis

Bristol-Myers Squibb

Cymbalta

Jazz Pharmaceuticals

Xarelto

Coreg

Akero Therapeutics

Vibramycin

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Lovenox

Cabenuva

Bayer Aspirin

Lovenox

Prevymis

CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Prophylaxis3 trials

Evaluation of PrEP-30: a Demonstration Project of Pre-exposure Prophylaxis for MSM and Other High-risk Group Clients at the Thai Red Cross Anonymous Clinic

Enrolling by invitation·TThai Red Cross AIDS Research Centre··NCT02437981·20,000 enrolled

Pre-exposure Prophylaxis: A Miracle Drug or a Moral Hazard

Completed·NNew York University··NCT04325555·2,647 enrolled

Storytelling to Increase Family Support for Pre Exposure Prophylaxis Use

Completed·VVanderbilt University Medical Center·N/A·NCT04071470·128 enrolled

PrEP3 trials

Integrating Enhanced HIV PrEP Into a STI Clinic in Lilongwe

Completed·UUniversity of North Carolina, Chapel Hill··NCT05307991·249 enrolled

Partners PrEP Program

Completed·UUniversity of Washington··NCT03586128·1,381 enrolled

Mixed-methods Protocol for the WiSSPr Study: Women in Sex Work, Stigma and Psychosocial Barriers to Pre-exposure Prophylaxis in Zambia

Completed·CCentre for Infectious Disease Research in Zambia··NCT06898112·299 enrolled

Women3 trials

Alignment of PrEP Use With HIV Risk in Young Women and Men

Completed·UUniversity of Washington·Phase 4·NCT04664998·212 enrolled

Project EMPOWERING: Evidence-based PrEP for Justice-Involved Women and Their Risk Networks

Completed·YYale University·Phase 1·NCT03293290·105 enrolled

A Cohort for Evaluation of Open-label PrEP Use and PreP Preferences Among African Women

Completed·UUniversity of Washington··NCT05746065·3,087 enrolled

ART1 trial

The Partners Scale-Up Project

Completed·UUniversity of Washington·Phase 4·NCT03052010·4,898 enrolled

HIV-11 trial

Safer Conception Intervention for HIV-1 Serodiscordant Couples

Completed·UUniversity of Washington··NCT03030768·74 enrolled

7 more indications

Liver1 trial

Virtual PrEP: Rendering PrEP Delivery More Efficient

Terminated·UUnity Health Toronto·Phase 4·NCT05159531·2 enrolled

HIV Prevention1 trial

PrEParing Family Planning Clinics to Streamline Integration of HIV Prevention Services for Young Women in Kenya

Completed·UUniversity of Washington·Phase 4·NCT04666792·25,457 enrolled

Effectiveness1 trial

The Impact and Cost-effectiveness of Safer Conception Strategies for HIV-discordant Couples (SAFER)

Completed·UUniversity of California, San Francisco··NCT03049176·46 enrolled

Female1 trial

IPREP Study #2: Evaluating Enhanced PrEP Packages for Young Female Sex Workers in Kisumu, Kenya

Completed·—·N/A·NCT03988387·200 enrolled

Fall1 trial

Parrying the Pitfalls of PrEP: Project PEACH

Completed·EEmory University·Phase 4·NCT05072093·240 enrolled

Pre-Exposure Prophylaxis (PrEP)1 trial

Pre-exposure Prophylaxis (PrEP) Adherence Enhancement Guided by iTAB and Drug Levels for Women

Completed·UUniversity of California, Los Angeles·Phase 4·NCT02584140·136 enrolled

Telemedicine1 trial

Providing Suboxone and PrEP Using Telemedicine

Completed·—·N/A·NCT04521920·17 enrolled

Sources

References

[1]
ClinicalTrials.gov — 18 trial records for PrEP. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — PrEP compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for PrEP. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — University of Washington company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: UUniversity of Washington

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