Psilocybin therapy

Phase 2Small molecule

UUniversity of California, San Francisco

Psilocybin therapy is one of 36 small molecule programs targeting Bipolar II Disorder. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Bipolar II DisorderActive, not recruiting

AnxietyActive, not recruiting

Bipolar II DisorderPhase 2

Active, not recruiting

AnxietyPhase 2

Active, not recruiting

Competition

Competitive Landscape

165 competitors in Anxiety

#DrugCompanyPhaseTrials

Circadin

NNeurim Pharmaceuticals Ltd.

Phase 3

4 2

Valium

Akero Therapeutics

Phase 3

2 3

Duragesic

CCephalon

Phase 3

1 4

Duloxetine Hydrochloride

Eli Lilly

Phase 3

—5

Yohimbine Hydrochloride

UUnknown Sponsor

Phase 3

1 6

Celexa

AbbVie

Preclinical

1 7

Spravato

WWim Janssens

Preclinical

4 8

Campral

FForest Laboratories

Preclinical

2 9

Luvox

SSolvay Pharmaceuticals

Preclinical

2 10

Anerem

AAcacia Pharma Ltd

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2027

Phase 2Recruiting

Psilocybin-Assisted Psychotherapy

NCT07072728

Q1 2028

Phase 2Not yet recruiting

Psilocybin

NCT06782724

Clinical

Trials by Indication[1]

Psilocybin-Assisted Psychotherapy1 trial

Psilocybin-Assisted Psychotherapy in Cancer Patients With Adjustment Disorder

Recruiting·PPsyence Australia Pty Ltd·Phase 2·NCT07072728·87 enrolled

Anxiety1 trial

Psilocybin Therapy for Depression and Anxiety in Parkinson's Disease

Completed·JJoshua Woolley, MD, PhD·Phase 2·NCT04932434·12 enrolled

Psilocybin1 trial

Psilocybin Therapy for Psychological Distress in Palliative Patients

Not yet recruiting·UUniversity Medical Center Groningen·Phase 2·NCT06782724·108 enrolled

Alcohol Use Disorder1 trial

Psilocybin in Alcohol Use Disorder With Comorbid Depression

Completed·—·N/A·NCT06235411·30 enrolled

Bipolar II Disorder1 trial

Psilocybin Therapy for Depression in Bipolar II Disorder

Active, not recruiting·UUniversity of California, San Francisco·Phase 2·NCT05065294·14 enrolled

Sources

References

[1]
ClinicalTrials.gov — 5 trial records for Psilocybin therapy. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Psilocybin therapy compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Psilocybin therapy. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — University of California, San Francisco company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: UUniversity of California, San Francisco

Psilocybin therapy

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2027

Q1 2028

Trials by Indication[1]

Psilocybin-Assisted Psychotherapy1 trial

Anxiety1 trial

Psilocybin1 trial

Alcohol Use Disorder1 trial

Bipolar II Disorder1 trial

References

Drug Info

Quick Facts

Related News