ROC-101

Phase 2Small molecule

ROC-101 is one of 4 small molecule programs targeting Pulmonary Arterial Hypertension (PAH). It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Pulmonary Arterial Hypertension (PAH)Recruiting

Pulmonary Arterial Hypertension (PAH)Phase 2

Recruiting

Competition

Competitive Landscape

4 competitors in Pulmonary Arterial Hypertension (PAH)

#DrugCompanyPhaseTrials

Intropin

Pfizer

Preclinical

1 2

Levophed

GGeneral Hospital of Ningxia Medical University

Preclinical

1 3

Adrenaline

SSamson Clinical Operations Pty Ltd

Preclinical

1 4

ROC-101

AAllRock Bio, Inc.

Phase 2

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2029

Phase 2Recruiting

Pulmonary Arterial Hypertension (PAH)

NCT07175038

Clinical

Trials by Indication[1]

Pulmonary Arterial Hypertension (PAH)1 trial

A Phase 2A, Open-Label Single Arm Multicenter Exploratory Study to Evaluate the Safety, Tolerability, and Efficacy of Oral Doses of ROC-101 in Patients With Pulmonary Arterial Hypertension (PAH) and Pulmonary Hypertension Associated With Interstitial Lung Disease (ILD-PH).

Recruiting·AAllRock Bio, Inc.·Phase 2·NCT07175038·40 enrolled

Sources

References

[1]
ClinicalTrials.gov — 1 trial record for ROC-101. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — ROC-101 compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for ROC-101. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — AllRock Bio, Inc. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: AAllRock Bio, Inc.

ROC-101

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2029

Trials by Indication[1]

Pulmonary Arterial Hypertension (PAH)1 trial

References

Drug Info

Quick Facts

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