Pentothal

(Thiopental)

ApprovedSmall molecule

AAbbott

Pentothal is one of 84 small molecule programs targeting Alcohol Dependence. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

FDA Application

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

Alcohol DependenceActive, not recruiting

MemoryActive, not recruiting

Alcohol DependencePreclinical

Active, not recruiting

MemoryApproved

Active, not recruiting

Competition

Competitive Landscape

52 competitors in Alcohol Dependence

#DrugCompanyPhaseTrials

Revia

Teva

Approved

21 2

Minipress

Pfizer

Approved

3 3

Antabuse

Teva

Approved

1 4

Depacon

AbbVie

Approved

1 5

Topamax

WWim Janssens

Approved

6 6

Selincro

IIndivior Inc.

Approved

5 7

Campral

FForest Laboratories

Approved

4 8

Zoloft

VViatris Specialty LLC

Approved

4 9

Vimpat

Celexa

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

IVF Outcome1 trial

Comparative Effect of Theipoental and Propofol in IVF Outcome

Completed·—·Phase 4·NCT02377778·180 enrolled

Remifentanil1 trial

The Effects of Remifentanil and Remifentanil-Alfentanil Administration in Children

Completed·HHallym University Medical Center·N/A·NCT02486926·102 enrolled

Septic Shock1 trial

Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock

Completed·—·Phase 3·NCT03104140·26 enrolled

Intracranial Hypertension1 trial

Comparison of Effectiveness of Pentobarbital and Thiopental in Patients With Refractory Intracranial Hypertension

Terminated·HHospital Universitari Son Dureta·Phase 3·NCT00622570·44 enrolled

Alcohol Dependence1 trial

GABA Mechanisms Underlying the Vulnerability to Alcohol Dependence

Completed·YYale University·N/A·NCT00611767·73 enrolled

3 more indications

Nitric Oxide1 trial

The Effects of Propofol and Thiopental on Nitric Oxide Production and Release in Erythrocytes

Completed·MMelike Cengiz·N/A·NCT06485388·12 enrolled

Memory1 trial

Neuroimaging the Effects of Intravenous Anesthetic on Amygdala Dependent Memory Processes

Terminated·WWeill Medical College of Cornell University·Phase 4·NCT00504894·60 enrolled

Propofol1 trial

Onset Time of Thiopental Versus Propofol in the Elderly

Completed·RRigshospitalet, Denmark·Phase 4·NCT00965107·78 enrolled

Regulatory

FDA Approval Timeline[4]

Jan 1, 1982

PENTOTHAL

NDA NDA011679

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Thiopental. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Thiopental compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Thiopental. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA011679). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Abbott company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: AAbbott

Pentothal

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

IVF Outcome1 trial

Remifentanil1 trial

Septic Shock1 trial

Intracranial Hypertension1 trial

Alcohol Dependence1 trial

Nitric Oxide1 trial

Memory1 trial

Propofol1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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