Trospium Chloride

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Overactive BladderUrinary Bladder, Overactive

150 competitors in Overactive Bladder

#DrugCompanyPhaseTrials

1

Botox

VVitae Pharmaceuticals Inc., an Allergan affiliate

Phase 3

32

Botox

AbbVie

Phase 3

33

GSK1358820

GSK

Phase 3

14

Tolterodine PR

Pfizer

Phase 3

55

Trospium Chloride

AbbVie

Approved

26

Oxybutynin Chloride

Mylan Pharmaceuticals Inc

Phase 3

37

Vesicare

Astellas

Phase 3

28

YM178

Astellas

Phase 3

69

SPM 907

Pfizer

Phase 3

510

Onabotulinumtoxina 100 UNT

SStanford University

Phase 3

1Show 18 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Trial2 trials

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART) Trial

Completed·AbbVie·Phase 4·NCT00863551·12 enrolled

Sanctura Muscarinic Receptor Antagonist Resists Transport (SMART-II) Trial

Completed·AbbVie·Phase 4·NCT01178827·20 enrolled

Overactive Bladder2 trials

Trospium Chloride XR in Obese Female Patients With Overactive Bladder

Completed·AbbVie·Phase 4·NCT00932022·127 enrolled

Efficacy of Sanctura XR (Trospium Chloride) for Reducing Overactive Bladder Symptoms in Female Subjects Refractory to Detrol LA (Tolterodine Tartrate Extended Release) Daily

Completed·AbbVie·Phase 4·NCT01089751·322 enrolled

Prevention1 trial

Gabapentin Versus Trospium Chloride for Prevention of a Catheter-related Bladder Discomfort Inside the ICU

Completed·—·Phase 4·NCT06346522·120 enrolled

Metformin1 trial

Safety and Tolerability of Trospium Chloride and Metformin Hydrochloride in Healthy Subjects

Completed·AbbVie·Phase 1·NCT00986401·44 enrolled

Treatment1 trial

Trospium Chloride vs Tamsulosin in Treatment of Ureteral Stent Related Symptoms:

Suspended·MMansoura University·N/A·NCT03709992·200 enrolled

5 more indications

Cognitive Function1 trial

The Effect of Anticholinergics on Cognitive Function in the Elderly

Completed·UUniversity of North Carolina, Chapel Hill·Phase 4·NCT01922115·59 enrolled

Pilot Study1 trial

Pilot Study Comparing Effects of Xanomeline Alone to Xanomeline Plus Trospium

Completed·KKaruna Therapeutics·Phase 1·NCT02831231·70 enrolled

Botox1 trial

Anticholinergic vs. Botox Comparison Study

Completed·NNICHD Pelvic Floor Disorders Network·Phase 3·NCT01166438·249 enrolled

Urinary Bladder, Overactive1 trial

Comparative Effectiveness of Pelvic Floor Muscle Training, Mirabegron, and Trospium Among Older Women With Urgency Urinary Incontinence and High Fall Risk: a Feasibility Randomized Clinical Study

Completed·TThe University of Texas Medical Branch, Galveston·Phase 1·NCT05880862·48 enrolled

Unspecified1 trial

Phase 1, 3-Part, Open-label Study to Evaluate the Pharmacokinetics of Novel KarX (BMS-986519) and KarT (BMS-986520) Prototypes Versus the KarXT (BMS-986510) and KarX-EC (BMS-986519) Reference Following Single Doses, and to Explore the Effect of Food After Multiple Doses of Selected Prototypes in Healthy Adult Participants

Recruiting·Bristol-Myers Squibb·Phase 1·NCT07063342·72 enrolled

Details

Drug Info

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