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Other/Analgesia

Analgesia

62

Pipeline Programs↗

96

Active Trials↗

27

Companies Involved↗

Analgesia is a moderately active landscape with 62 programs across 27 companies. 14 programs are in Phase 3.

Intelligence

Pipeline Metrics

Competitive Density

70/100

Pipeline Velocity

65/100

Mech. Concentration

24/100

Completion Rate

84/100

Attrition Rate

11/100

Pipeline

Programs by Phase

Preclinical42

Remifentanyl

Assistance Publique - Hôpitaux de Paris

Rescue IA

Medical University of Silesia

Alfentanil

Jazz Pharmaceuticals

Flurbiprofen Axetil

Sun Yat-sen University

Ramosetron

Astellas

Phase 14

Naloxone

Scienture

Bupivacaine

Innocoll

Triamcinolone

Bassett Healthcare

Liposomal Irinotecan and Apatinib

Second Affiliated Hospital, School of Medicine, Zhejiang University

Phase 22

HRS-2129

Shandong Suncadia Medicine Co., Ltd.

TRD205

Beijing Tide Pharmaceutical Co., Ltd

Phase 314

Ketamine Hydrochloride

Boehringer Ingelheim

Esketamine Combined With Dexmedetomidine

The First Affiliated Hospital with Nanjing Medical University

Intrathecal Morphine

Pacira Pharmaceuticals, Inc

Methoxyflurane

Purdue Pharma, Canada

Oxycodone Hydrochloride

Purdue Pharma LP

Approved

No programs

Analysis

Trial Status

524

clinical trials

Completed299 · 57%

Unknown status71 · 14%

Recruiting41 · 8%

Not yet recruiting38 · 7%

Terminated37 · 7%

Withdrawn20 · 4%

Other18 · 3%

Clinical Trials

Trial Activity

524 trials

Predictors of Maladaptive Behaviors in Children Undergoing Procedural Sedation

Recruiting·LLondon Health Sciences Centre Research Institute·N/A·NCT07495826·2,145 enrolled

Analysis of the Incidence and Risk Factors of Epidural Analgesia Failure During Labor: A Prospective Multicenter Observational Study

Recruiting·—·N/A·NCT07473609·500 enrolled

Efficacy of Ultrasound-guided Sacral Multifidus Plane Block as Perioperative Analgesia for Anal and Penile Surgeries in High-risk Pediatric Patients

Recruiting·ZZagazig University·Preclinical·NCT07602894·60 enrolled

Impact of the EpiFaith® Syringe on the Learning Curve of Anesthesia Residents for the Labor Epidural Technique: A Quasi-Experimental Study

Recruiting·BBrigham and Women's Hospital·Preclinical·NCT07395622·34 enrolled

Evaluation of the Effect of Ultrasound-Guided Bilateral Recto-Intercostal Fascial Plane Block on Postoperative Pain, Opioid Consumption, and Quality of Recovery in Laparoscopic Cholecystectomy Surgery: A Prospective, Randomized, Double-Blind Controlled Clinical Study

Recruiting·IIstinye University·Preclinical·NCT07745972·60 enrolled

A Comparison of Nausea and Vomiting in Postoperative Paediatric Patients With Patient-controlled Analgesia (PCA): Morphine vs Oxycodone (POPCORN)

Recruiting·MMurdoch Childrens Research Institute·Approved·NCT06186141·690 enrolled

Comparison of the Analgesic Effects of Ultrasound-Guided Transversalis Fascia Plane Block and Transversus Abdominis Plane Block in Pediatric Laparoscopic Surgery

Recruiting·SSakarya University·N/A·NCT07242196·36 enrolled

Efficacy of Single Level Versus Bilevel Serratus Anterior Plane Block With Dexmedetomidine During Breast Cancer Surgery

Recruiting·National Cancer Institute, Egypt·Preclinical·NCT05361837·172 enrolled

Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain

Recruiting·National Cancer Institute, Egypt·Preclinical·NCT05851768·60 enrolled

a Comparive Study of Ketamine-Propofol Versus Dexmedetomidine-Propofol Sedation in Pediatric Patients Undergoing Cardiac Catheterization for Device Closure of Simple Left-to-right Shunts

Recruiting·AAin Shams University·Phase 1·NCT07669012·124 enrolled

Long Term Safety of Preoperative Percutaneous Intercostal Cryoneurolysis: Neuropathic Pain, Quality of Life and Sensory Recovery in a Paediatric Cohort Following Pectus Excavatum Repair

Recruiting·Papa Giovanni XXIII Hospital·N/A·NCT07657845·50 enrolled

Prehospital Analgesia INtervention Trial (PAIN)

Recruiting·—·Phase 3·NCT05437575·994 enrolled

Intrathecal Versus Epidural Morphine for Post-Cesarean Analgesia

Recruiting·HHospital Central do Funchal·Phase 4·NCT07386353·120 enrolled

Determining the Optimal Dose of Intrathecal Morphine for Post-Cesarean Analgesia

Recruiting·UUniversity of Ioannina·N/A·NCT07023497·100 enrolled

Serratus Posterior Superior Intercostal Plane Block for Analgesia in Off-Pump Minimally Invasive CABG

Recruiting·—·N/A·NCT07412522·60 enrolled

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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)