VivoSeq
Other

Bupivacaine

2

Pipeline Programs↗

11

Active Trials↗

3

Companies Involved↗

Bupivacaine is an early-stage landscape with 2 programs across 3 companies. The most active players are Heron Therapeutics, Grace Therapeutics Inc., AstraZeneca. 2 therapies are approved.

Intelligence

Pipeline Metrics

Competitive Density

32/100

Pipeline Velocity

22/100

Mech. Concentration

100/100

Completion Rate

82/100

Attrition Rate

11/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

H

Heron Therapeutics

0 programs

PreclinicalG

Grace Therapeutics Inc.

0 programs

PreclinicalAstraZeneca logo

AstraZeneca

0 programs

Preclinical

Pipeline

Programs by Phase

Preclinical
No programs
Phase 1
No programs
Phase 2
No programs
Phase 3
No programs
Approved2

Bupivacaine Liposomes(bl)

Huazhong University of Science and Technology

Bupivacaine

Innocoll

Analysis

Trial Status

118

clinical trials

Completed75 · 64%
Unknown status16 · 14%
Withdrawn7 · 6%
Recruiting6 · 5%
Terminated6 · 5%
Not yet recruiting4 · 3%
Other4 · 3%

Clinical Trials

Trial Activity

118 trials

Intrathecal Bupivacaine With or Without Dexmetomidine for Cesserian Delivery
Recruiting·—·Phase 2·NCT07465185·300 enrolled
Local LevoBupivacaine for Pain Relief After Endoscopic Submucosal Dissection for Esophageal Lesions
Recruiting·—·N/A·NCT06611176·88 enrolled
Efficacy of EXPAREL vs. Bupivacaine
Recruiting·EEmory University·Phase 3·NCT07212114·104 enrolled
Intravesical Bupivacaine on Post-Operative Ureteroscopy Pain
Recruiting·UUniversity of Chicago·Phase 2·NCT06635889·116 enrolled
Bupivacaine and Epinephrine Injection Study
Recruiting·—·Phase 2/3·NCT06456255·80 enrolled
Effect of Bupivacaine Liposomes or Bupivacaine for Ultrasound-guided CMB on Postoperative Analgesia in Laparoscopic Hepatobiliary Pancreatic Surgery: a Prospective, Single Blind, Completely Randomized, Active Controlled Clinical Trial
Recruiting·HHuazhong University of Science and Technology·Approved·NCT06737341·60 enrolled
Bupivacaine With Epinephrine Over Diaphragm in Laparoscopy
Not yet recruiting·—·Phase 4·NCT07400146·100 enrolled
Effect of Hyaluronidase in Different Doses Added to Bupivacaine on TAB Block Quality During CS
Not yet recruiting·—·Phase 1·NCT06839391·120 enrolled
Dexmeditomedine as an Adjuvant to Levobupivacaine in Transversus Thoracis Plane Block on the Management of Post-sternotomy Pain in Open-heart Surgeries
Not yet recruiting·—·N/A·NCT06410404·60 enrolled
Analgesic Effect of Bupivacaine Plus Ketamine Versus Bupivacaine Alone in Transversalis Fascia Plane Block
Not yet recruiting·—·Phase 1·NCT06935669·68 enrolled
Mepivacaine Versus Bupivacaine Onset Time in Ultrasound-guided Ankle Blocks
Enrolling by invitation·MMayo Clinic·Phase 4·NCT05425979·50 enrolled
Bupivacaine Liposome Suspension Versus a Concentrated Multi Drug Periarticular Injection
Completed·TTriHealth Inc.·N/A·NCT02299349·70 enrolled
Comparing Ropivacaine and Bupivacaine in DTFNB Anesthesia in Patients Undergoing Phacoemulsification
Completed·GGovernment Medical College, Haldwani·N/A·NCT02925832·100 enrolled
Duration of Blockade of Peripheral Nerves With Bupivacaine Depending of the Adjuvants
Completed·LLviv National Medical University·N/A·NCT04498923·68 enrolled
Rofecoxib and Bupivacaine to Prevent Pain After Third Molar (Wisdom Tooth) Extraction
Completed·National Institute of Dental and Craniofacial Research (NIDCR)·Phase 2·NCT00050362·136 enrolled
Page 1 of 8

Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)