VivoSeq
Other

Cachexia

36

Pipeline Programs

14

Active Trials

24

Companies Involved

Cachexia is a moderately active landscape with 36 programs across 24 companies. The most active players are AVEO Pharmaceuticals, Inc., Genfleet Therapeutics (Shanghai) Inc., Jiangsu Nutai Biologics Co., Ltd. 3 therapies are approved with 7 more in late-stage development.

Pipeline Metrics

Competitive Density

57/100

Pipeline Velocity

22/100

Mech. Concentration

17/100

Completion Rate

75/100

Attrition Rate

11/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

85%

Small molecule

33 of 39 classified programs — the dominant modality here.

15%ALL OTHERSMonoclonal antibody410%Protein / enzyme13%Peptide13%

Small molecule leads; the ring shows all 39 classified programs, each share of the total. Modality classified for 98% of 42 pipeline programs.

Trial Status

37

clinical trials

Completed15 · 41%
Recruiting9 · 24%
Terminated4 · 11%
Not yet recruiting3 · 8%
Active, not recruiting2 · 5%
Unknown status2 · 5%
Other2 · 5%

Trial Activity

37 trials

A Study of JMT203 in Patients With Cancer Cachexia
Recruiting·SShanghai JMT-Bio Inc.·Phase 1·NCT06868849·130 enrolled
Visugromab in Cachexia International Trial
Recruiting·CCatalYm GmbH·Phase 2/3·NCT07112196·518 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)