VivoSeq
Musculoskeletal

Rib Fracture

31

Pipeline Programs↗

9

Active Trials↗

13

Companies Involved↗

Rib Fracture is a moderately active landscape with 31 programs across 13 companies. The most active players are Viatris Specialty LLC, Hikma Pharmaceuticals LLC, Pfizer. 18 therapies are approved with 3 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

54/100

Pipeline Velocity

15/100

Mech. Concentration

18/100

Completion Rate

39/100

Attrition Rate

38/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

V

Viatris Specialty LLC

1 program

Phase 1H

Hikma Pharmaceuticals LLC

1 program

Phase 3Pfizer logo

Pfizer

2 programs

Phase 3K

Kenvue Brands

2 programs

ApprovedPacira Pharmaceuticals, Inc logo

Pacira Pharmaceuticals, Inc

2 programs

ApprovedM

Milestone Pharmaceuticals Inc.

1 program

Approved

Pipeline

Programs by Phase

Analysis

Trial Status

37

clinical trials

Terminated10 · 27%
Completed9 · 24%
Unknown status5 · 14%
Recruiting4 · 11%
Withdrawn4 · 11%
Active, not recruiting2 · 5%
Other3 · 8%

Clinical Trials

Trial Activity

37 trials

Breathing Exercise for Rib Fracture
Recruiting·KKastamonu University·N/A·NCT06222333·62 enrolled
Cryo Rib Fracture Study
Recruiting·UUniversity of Minnesota·Phase 4·NCT06347874·48 enrolled
Ultrasound Guided Serratus Anterior Plane Block for Rib Fractures
Recruiting·WWellSpan Health·N/A·NCT05748366·60 enrolled
INTERCOSTAL NERVE BLOCK: Efficacy of CINB for Patients With Multiple Rib Fractures
Recruiting·—·Phase 4·NCT05642026·180 enrolled
Analgesic Techniques for Rib Fractures
Active, not recruiting·TThomas Jefferson University·Phase 4·NCT06519929·24 enrolled
Ketamine vs Lidocaine in Traumatic Rib Fractures
Active, not recruiting·—·Phase 4·NCT04781673·74 enrolled
Comparison of Continuous Intravenous Lidocaine Infusion Versus ESP Block for Rib Fracture Analgesia
Not yet recruiting·SStanford University·Phase 2·NCT04707183·160 enrolled
Role of Nerve Block in Management of Multiple Rib Fractures
Not yet recruiting·—·Phase 4·NCT06958549·74 enrolled
Suzetrigine for Acute Pain Control in Patients With Multiple Rib Fractures
Enrolling by invitation·UUniversity of California, Irvine·Phase 4·NCT07145346·80 enrolled
Efficacy of Gabapentin vs. Placebo for Adjuvant Pain Control Following Acute Rib Fractures
Completed·—·Phase 1·NCT02856750·100 enrolled
Ultrasound- Guided Continuous Retro Laminar Block Versus Continuous Erector Spinae Plane Block in Multiple Rib Fractures
Completed·TTanta University·N/A·NCT06088836·60 enrolled
Dexmedotomidine for Acute Pain Control in Patients With Multiple Rib FracturesRandomized Controlled Trial
Completed·UUniversity of California, Irvine·Phase 4·NCT05321121·41 enrolled
Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients
Completed·MMedical College of Wisconsin·Phase 4·NCT02432456·153 enrolled
Lidocaine Spray for Pain Control in Rib Fractures
Completed·—·Phase 4·NCT05500677·48 enrolled
Rib Fracture Analgesia Using Cryoanalgesia
Completed·UUniversity of California, San Diego·Phase 4·NCT04198662·20 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)