VivoSeq
Neurology

Spinal Cord Injury

154

Pipeline Programs↗

49

Active Trials↗

74

Companies Involved↗

Spinal Cord Injury is a highly competitive landscape with 154 programs across 74 companies. The most active players are Tanabe Pharma America, Inc., AlaMab Therapeutics (Shanghai) Inc., NovaGo Therapeutics AG. 33 therapies are approved with 18 more in late-stage development.

Intelligence

Pipeline Metrics

Competitive Density

78/100

Pipeline Velocity

45/100

Mech. Concentration

7/100

Completion Rate

79/100

Attrition Rate

12/100

Competition

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Key Players

Top Companies Companies ranked by the number of pipeline programs they run for this disease.

T

Tanabe Pharma America, Inc.

1 program

Phase 1A

AlaMab Therapeutics (Shanghai) Inc.

1 program

Phase 1N

NovaGo Therapeutics AG

1 program

Phase 1B

Bukwang Pharmaceutical

1 program

Phase 1A

Adaptive Phage Therapeutics, Inc.

1 program

Phase 1J

Jiangsu Topcel-KH Pharmaceutical Co., Ltd.

1 program

Phase 1

Pipeline

Programs by Phase

Analysis

Modality Breakdown

88%

Small molecule

150 of 171 classified programs — the dominant modality here.

12%ALL OTHERSCell therapy148%Monoclonal antibody42%Peptide21%Protein / enzyme1<1%

Small molecule leads; the ring shows all 171 classified programs, each share of the total. Modality classified for 99% of 191 pipeline programs.

Analysis

Trial Status

214

clinical trials

Completed105 · 49%
Unknown status31 · 14%
Recruiting26 · 12%
Terminated19 · 9%
Not yet recruiting12 · 6%
Active, not recruiting7 · 3%
Other14 · 7%

Clinical Trials

Trial Activity

214 trials

Calcitonin Therapy on Incidence and Severity of Neuropathic Pain After Spinal Cord Injury
Recruiting·TTanta University·N/A·NCT05805683·50 enrolled
PMZ-1620 (Sovateltide) in Patients of Acute Spinal Cord Injury
Recruiting·PPharmazz, Inc.·Phase 2·NCT04054414·40 enrolled
Improvement of Reproductive Function in Men With Spinal Cord Injury (SCI)
Recruiting·UUniversity of Miami·Phase 3·NCT05903859·90 enrolled
Bacteriophage Therapy in Spinal Cord Injury Patients With Bacteriuria
Recruiting·—·Phase 1·NCT06559618·30 enrolled
Prophylactic Pregabalin Treatment Following Spinal Cord Injury
Recruiting·—·N/A·NCT06066918·50 enrolled
Safety and Early Efficacy of iPSC-Derived Motor Neuron Progenitor Cells (XS228) in Subacute Spinal Cord Injury: A Phase I Trial
Recruiting·XXellSmart Bio-Pharmaceutical (Suzhou) Co., Ltd.·Phase 1·NCT06976229·12 enrolled
Prevention of Thromboembolism Using Apixaban vs Enoxaparin Following Spinal Cord Injury
Recruiting·—·N/A·NCT05484557·60 enrolled
Can Brief Exposure to Hyperoxia Improve Function After Chronic Spinal Cord Injury?
Recruiting·UUniversity of Alberta·Phase 1·NCT05467215·25 enrolled
CBD for Lower Urinary Tract Dysfunction in Spinal Cord Injury
Recruiting·UUniversity of Wisconsin, Madison·Phase 2·NCT06840899·20 enrolled
NG004 in Spinal Cord Injury Patients
Recruiting·NNovaGo Therapeutics AG·Phase 1·NCT06817577·21 enrolled
Spinal Cord Injury Neuroprotection With Glyburide
Recruiting·—·Phase 1·NCT05426681·12 enrolled
Treating Central Neuropathic Pain With Low Dose Naltrexone for People With Spinal Cord Injury
Recruiting·MMedical College of Wisconsin·Phase 2·NCT06723561·10 enrolled
A Study to Evaluate the Safety of a Delivery Device for Administering LCTOPC1 in Participants With Spinal Cord Injury
Recruiting·LLineage Cell Therapeutics, Inc.·Phase 1·NCT06841770·10 enrolled
Contrast-enhanced Ultrasound in the Treatment of Acute Spinal Cord Injury
Recruiting·UUniversity of Washington·Phase 4·NCT06654804·50 enrolled
Locomotor Training With Testosterone to Promote Bone and Muscle Health After Spinal Cord Injury
Recruiting·NNorth Florida Foundation for Research and Education·Phase 2·NCT04460872·21 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)