Adjuvant Chemotherapy

Phase 3Small molecule

NNizhny Novgorod Regional Clinical Oncology Center

Adjuvant Chemotherapy is one of 565 small molecule programs targeting Pancreatic Carcinoma. It is currently in Phase 3.

Indications

Total Trials

Active Trials

564

Competitors

Pipeline

Status by Indication[3][1]

Indication

Pancreatic CarcinomaActive, not recruiting

Gallbladder CarcinomaActive, not recruiting

Nasopharyngeal CarcinomaActive, not recruiting

Lung CancerActive, not recruiting

Esophageal CancerActive, not recruiting

Malignant Pleural MesotheliomaActive, not recruiting

Gastric AdenocarcinomaActive, not recruiting

AdenocarcinomaActive, not recruiting

Triple-Negative Breast CancerActive, not recruiting

Pancreatic Ductal AdenocarcinomaActive, not recruiting

Pancreatic CarcinomaPhase 2

Active, not recruiting

Gallbladder CarcinomaPhase 3

Active, not recruiting

Nasopharyngeal CarcinomaPhase 3

Active, not recruiting

Lung CancerPhase 3

Active, not recruiting

Esophageal CancerPhase 3

Active, not recruiting

Malignant Pleural MesotheliomaPhase 2

Active, not recruiting

Gastric AdenocarcinomaPhase 2/Phase 3

Active, not recruiting

AdenocarcinomaPreclinical

Active, not recruiting

Triple-Negative Breast CancerPreclinical

Active, not recruiting

Pancreatic Ductal AdenocarcinomaPreclinical

Active, not recruiting

Showing 10 of 22 indications

Competition

Competitive Landscape

2828 competitors in Breast Cancer

#DrugCompanyPhaseTrials

Adjuvant Chemotherapy

NNizhny Novgorod Regional Clinical Oncology Center

Phase 3

2 2

Tykerb

GSK

Preclinical

80 3

Adriamycin

GGynecologic Oncology Group

Preclinical

87 4

Prolia

Amgen

Preclinical

14 5

Gemzar

GGynecologic Oncology Group

Preclinical

22 6

Megace

Bristol-Myers Squibb

Preclinical

4 7

Spravato

WWim Janssens

Preclinical

2 8

Chirocaine

PPurdue Pharma LP

Preclinical

1 9

Avastin

Roche

Preclinical

4 10

Feraheme

AAzurity Pharmaceuticals

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2026

N/ARecruiting

Randomized Controlled Trial

NCT05496491

Q4 2026

Phase 3Recruiting

Colon Cancer

NCT05194878

Recruiting

Urothelial Carcinoma

NCT05595408

Q2 2027

N/AActive, not recruiting

Non-Small Cell Lung Cancer

NCT01817192

Q3 2027

N/ANot yet recruiting

Locally Advanced Colon Cancer

NCT07413146

Phase 2Active, not recruiting

Glioblastoma

NCT04747145

Clinical

Trials by Indication[1]

Ovarian Cancer6 trials

SUROVA - Surgery in Ovarian Cancer, Comparing Primary and Interval Cytoreductive Surgery

Unknown status·—··NCT06223763·5,000 enrolled

HOT: HIPEC in Ovarian Cancer as Initial Treatment

Active, not recruiting·MMercy Medical Center·Phase 2·NCT02124421·32 enrolled

Short-course HIPEC in Advanced Epithelial Ovarian Cancer

Completed·PProfessor Fernando Figueira Integral Medicine Institute·Phase 2·NCT02249013·15 enrolled

Show 3 more trials

Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery

Unknown status·—·Phase 3·NCT03373058·310 enrolled

Efficacy of HIPEC as NACT and Postoperative Chemotherapy in the Treatment of Advanced-Stage Epithelial Ovarian Cancer

Unknown status·SShu-Zhong Cui·Phase 3·NCT03180177·263 enrolled

Phase III Trial of Stage I Ovarian Cancer After Surgery

Recruiting·JJapanese Gynecologic Oncology Group·Phase 3·NCT04063527·360 enrolled

Gastric Cancer5 trials

Neoadjuvant Chemoradiotherapy vs. Chemotherapy Followed by Radical Gastrectomy and Adjuvant Chemotherapy for Advanced Gastric Cancer

Completed·SSun Yat-sen University·Phase 3·NCT01815853·620 enrolled

A Comparison of Laparoscopic With Open Distal Gastrectomy in Advanced Gastric Cancer After Neoadjuvant Chemotherapy

Unknown status·PPeking University·Phase 2·NCT02404753·102 enrolled

Randomized Phase II Trial Evaluating DFS in The Absence of an Adjuvant Component of Perioperative Chemotherapy in Patients With Gastric Cancer

Not yet recruiting·NNizhny Novgorod Regional Clinical Oncology Center·Phase 2·NCT06942663·228 enrolled

Show 2 more trials

Oncological Benefits of Pressured Intraperitoneal Aerosol Chemotherapy (PIPAC) in Patients With T3-4 Gastric Cancer Cyt-

Recruiting·SSt. Petersburg State Pavlov Medical University·N/A·NCT04595929·304 enrolled

Perioperative Chemotherapy Combined With HIPEC for High-risk Advanced Gastric Cancer

Unknown status·SSixth Affiliated Hospital, Sun Yat-sen University·Phase 3·NCT02960061·640 enrolled

Adjuvant Chemotherapy4 trials

The Clinical Study of Adjuvant Chemotherapy on Intestinal and Urethral Flora in Patients With Gastric and Colon Cancer

Unknown status·TThe First Affiliated Hospital of Dalian Medical University·N/A·NCT04198051·120 enrolled

ctDNA-Based Adjuvant Chemotherapy for High-Risk Rectal Cancer

Not yet recruiting·EErasmus Medical Center·Phase 3·NCT07188025·103 enrolled

Adjuvant Chemotherapy With FOLFOX in HCC Patients After Resection

Unknown status·SSun Yat-sen University·Phase 3·NCT02738697·290 enrolled

Show 1 more trial

Adjuvant Chemotherapy in Clinical Local Advanced CRC Following Preoperational Therapies and pT0-3N0M0 Diagnosis

Recruiting·SSixth Affiliated Hospital, Sun Yat-sen University·N/A·NCT03748485·650 enrolled

Triple-Negative Breast Cancer2 trials

Breast-Conserving Therapy in Patients With Triple-Negative Breast Cancer

Unknown status·XXiaoming Xie·N/A·NCT02464774·464 enrolled

OPTImaL:Optimisation of Treatment for Patients With Low Stage Triple-negative Breast Cancer With High Stromal Tumor-infiltrating Lymphocytes

Recruiting·TThe Netherlands Cancer Institute··NCT06476119·490 enrolled

Gastric Adenocarcinoma2 trials

Adujvant CT+CRT vs Adujvant CT After D2 Resection for Locally Advanced Proximal Gastric Adenocarcinoma

Unknown status·ZZhejiang Cancer Hospital·Phase 3·NCT03973008·408 enrolled

Preoperative Concurrent Chemoradiotherapy for Locally Advanced Gastroesophageal Junction or Upper Gastric Adenocarcinoma

Unknown status·PPeking University·Phase 2/3·NCT02193594·214 enrolled

29 more indications

Esophageal Cancer2 trials

Improve the Treatment of Thoracic Esophageal Cancer

Completed·SSun Yat-sen University·Phase 3·NCT01137123·301 enrolled

Adjuvant Therapies or Surgery Alone for High Risk pN0 Esophageal Cancer

Unknown status·SShanghai Chest Hospital·Phase 3·NCT02891083·486 enrolled

Cervical Cancer2 trials

Clinical Efficacy of the Neoadjuvant Chemotherapy for IB2 and IIA2 Stage Cervical Cancer Patients

Completed·HHuazhong University of Science and Technology·Phase 3·NCT03308591·774 enrolled

Clinical Efficacy of Adjuvant Chemotherapy in Patients With Locally Advanced Cervical Cancer Who Did Not Meet the NCCN Guidelines for Adjuvant Treatment After NACT Combined With Surgery

Recruiting·HHuazhong University of Science and Technology·Phase 3·NCT04733820·340 enrolled

Colorectal Cancer2 trials

Cytokine-induced Killer Cell Immunotherapy for Surgical Resected Stage III Colorectal Cancer Patients After Chemotherapy

Unknown status·SSun Yat-sen University·Phase 3·NCT02280278·550 enrolled

Adjuvant PD-1 Blockade for High-risk Stage-II DMMR/MSI-H Colorectal Cancer

Recruiting·SSun Yat-sen University·Phase 3·NCT06520683·180 enrolled

Non-Small Cell Lung Cancer2 trials

Adjuvant Chemotherapy in Patients With Intermediate or High Risk Stage I or Stage IIA Non-squamous Non-Small Cell Lung Cancer: AIM-HIGH (Adjuvant Intervention in Molecular High Risk Patients)

Active, not recruiting·RRazor Genomics·N/A·NCT01817192·420 enrolled

Perioperative Cemiplimab for Resectable Non-Small Cell Lung Cancer With High PD-L1

Not yet recruiting·HHenry Ford Health System·Phase 2·NCT07450183·33 enrolled

Breast Cancer2 trials

Phase II NCT (Neoadjuvant Chemotherapy) w/ Weekly Abraxane in Combination With Carboplatin & Bevacizumab in Breast Cancer

Completed·OOhio State University Comprehensive Cancer Center·Phase 2·NCT00675259·33 enrolled

Neoadjuvant SBRT Followed by Nab-Paclitaxel Combined With Toripalimab in HR+/HER2- Breast Cancer: A Single-arm, Prospective Clinical Trial

Recruiting·XXijing Hospital·Phase 2·NCT06914440·27 enrolled

Total Neoadjuvant Treatment1 trial

Total Neoadjuvant Treatment vs. Chemoradiotherapy in Local Advanced Rectal Cancer With High Risk Factors

Unknown status·WWest China Hospital·Phase 3·NCT03177382·458 enrolled

Cholangiocarcinoma1 trial

Role of Adjuvant Chemotherapy in Distal Cholangiocarcinoma

Completed·SSeoul National University Hospital··NCT06671431·578 enrolled

Pancreatic Ductal Adenocarcinoma1 trial

Adjuvant Chemoradiation Following Radical Resection of Pancreatic Ductal Adenocarcinoma, a Prospective Cohort Study

Unknown status·SShanghai Zhongshan Hospital··NCT04737551·400 enrolled

Pancreatic Carcinoma1 trial

Neoadjuvant mFolfirinox With or Without Preoperative Concomitant Chemoradiotherapy in Patients With Borderline Resectable Pancreatic Carcinoma (PANDAS-PRODIGE 44)

Active, not recruiting·IInstitut de Cancérologie de Lorraine·Phase 2·NCT02676349·130 enrolled

Rectal Cancer1 trial

Avoiding Surgery in Rectal Cancer After Pre-Operative Therapy

Unknown status·RRoyal Marsden NHS Foundation Trust·Phase 2·NCT01047969·99 enrolled

Pancreatic Adenocarcinoma1 trial

Neo-adjuvant FOLF(IRIN)OX for Resectable Pancreatic Adenocarcinoma

Completed·UUniversity Hospital, Rouen·Phase 2·NCT02959879·153 enrolled

Total Neoadjuvant Therapy1 trial

Total Neoadjuvant Therapy in Rectal Cancer Treatment

Unknown status·SState Scientific Centre of Coloproctology, Russian Federation·Phase 4·NCT04747951·280 enrolled

Adenocarcinoma1 trial

Quantitative Nodal Burden as a Determinant Identifying Ampullary Adenocarcinoma Patients Benefiting From Adjuvant Chemotherapy

Recruiting·—··NCT06435767·300 enrolled

Colon Cancer1 trial

Neoadjuvant FOLFOXIRI Versus Immediate Surgery for Stage II and III Colon Cancers

Recruiting·SSun Yat-sen University·Phase 3·NCT05194878·840 enrolled

Malignant Pleural Mesothelioma1 trial

Intrapleural Photodynamic Therapy in a Multimodal Treatment for Patients With Malignant Pleural Mesothelioma

Completed·UUniversity Hospital, Lille·Phase 2·NCT02662504·6 enrolled

Randomized Controlled Trial1 trial

Neoadjuvant Chemoradiotherapy and Consolidation Chemotherapy for Rectal Cancer: A Randomized Controlled Trial

Recruiting·LLarissa University Hospital·N/A·NCT05496491·84 enrolled

Urothelial Carcinoma1 trial

Circulating and Urine Tumor DNA Dynamics Predict Minimal Residual Disease and Recurrence Risk in Locally Advanced Upper Tract Urothelial Carcinoma

Recruiting·RRenJi Hospital··NCT05595408·84 enrolled

Neoadjuvant Chemotherapy1 trial

Outcome of Neoadjuvant Chemotherapy for Obstructive Colon Cancer

Not yet recruiting·TThe Catholic University of Korea·N/A·NCT04889820·204 enrolled

Immune Checkpoint Blockade1 trial

Study of an Individualized Vaccine Targeting Neoantigens in Combination With Immune Checkpoint Blockade for Patients With Colon Cancer

Withdrawn·GGritstone bio, Inc.·Phase 2·NCT05456165

Nasopharyngeal Carcinoma1 trial

A Trial of Adjuvant Chemotherapy in Nasopharyngeal Carcinoma Patients With Residual Epstein-Barr Virus (EBV) DNA Following Radiotherapy

Completed·—·Phase 3·NCT00370890·104 enrolled

Chemoradiotherapy1 trial

A Prospective Phase II Study of Individualized Neoadjuvant Chemoradiotherapy for Rectal Cancer Based on Recurrence Risk

Unknown status·—·Phase 2·NCT04664504·150 enrolled

Bladder Cancer1 trial

CD155 in Bladder Cancer

Completed·FFudan University··NCT03789682·151 enrolled

Locally Advanced Colon Cancer1 trial

Neoadjuvant CAPEOX Versus Upfront Surgery for Locally Advanced Colon Cancer With Elevated CEA: A Single-Center, Open-Label, Randomized Controlled Trial

Not yet recruiting·SSun Yat-sen University·N/A·NCT07413146·100 enrolled

Gallbladder Carcinoma1 trial

Neoadjuvant Chemotherapy With Gemcitabine Plus Cisplatin Followed by Radical Liver Resection Versus Immediate Radical Liver Resection Alone With or Without Adjuvant Chemotherapy in Incidentally Detected Gallbladder Carcinoma After Simple Cholecystectomy or in Front of Radical Resection of BTC

Completed·KKrankenhaus Nordwest·Phase 3·NCT03673072·68 enrolled

Pembrolizumab1 trial

Neoadjuvant Pembrolizumab With a Watch-and-wait Strategy for dMMR/MSI-H Localized Colon Cancer: PREMICES Study.

Not yet recruiting·GGERCOR - Multidisciplinary Oncology Cooperative Group·Phase 2·NCT06646445·60 enrolled

Pancreatic Cancer1 trial

Adjuvant Chemoradiotherapy Versus Chemotherapy for Pancreatic Cancer (ADJUPANC)

Recruiting·—·Phase 3·NCT06427447·770 enrolled

Lung Cancer1 trial

Neoadjuvant or Adjuvant Chemotherapy in Patients With Operable Non-small-cell Lung Cancer

Completed·SSpanish Lung Cancer Group·Phase 3·NCT00913705·624 enrolled

Patients With Locally Advanced Rectal Cancer1 trial

Efficacy and Safety of Conventional Neoadjuvant Therapy Versus Total Neoadjuvant Therapy in Older Patients With Locally Advanced Rectal Cancer

Recruiting·JJules Bordet Institute·N/A·NCT06052332·230 enrolled

Glioblastoma1 trial

Analyzing Pulsed Reduced Dose Radiotherapy in Upfront Glioblastoma

Active, not recruiting·MMedical College of Wisconsin·Phase 2·NCT04747145·38 enrolled

Sources

References

[1]
ClinicalTrials.gov — 53 trial records for Adjuvant Chemotherapy. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Adjuvant Chemotherapy compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Adjuvant Chemotherapy. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Nizhny Novgorod Regional Clinical Oncology Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: NNizhny Novgorod Regional Clinical Oncology Center

Adjuvant Chemotherapy

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2026

Q4 2026

Q2 2027

Q3 2027

Trials by Indication[1]

Ovarian Cancer6 trials

Gastric Cancer5 trials

Adjuvant Chemotherapy4 trials

Triple-Negative Breast Cancer2 trials

Gastric Adenocarcinoma2 trials

Esophageal Cancer2 trials

Cervical Cancer2 trials

Colorectal Cancer2 trials

Non-Small Cell Lung Cancer2 trials

Breast Cancer2 trials

Total Neoadjuvant Treatment1 trial

Cholangiocarcinoma1 trial

Pancreatic Ductal Adenocarcinoma1 trial

Pancreatic Carcinoma1 trial

Rectal Cancer1 trial

Pancreatic Adenocarcinoma1 trial

Total Neoadjuvant Therapy1 trial

Adenocarcinoma1 trial

Colon Cancer1 trial

Malignant Pleural Mesothelioma1 trial

Randomized Controlled Trial1 trial

Urothelial Carcinoma1 trial

Neoadjuvant Chemotherapy1 trial

Immune Checkpoint Blockade1 trial

Nasopharyngeal Carcinoma1 trial

Chemoradiotherapy1 trial

Bladder Cancer1 trial

Locally Advanced Colon Cancer1 trial

Gallbladder Carcinoma1 trial

Pembrolizumab1 trial

Pancreatic Cancer1 trial

Lung Cancer1 trial

Patients With Locally Advanced Rectal Cancer1 trial

Glioblastoma1 trial

References

Drug Info

Quick Facts

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