Artesunate-amodiaquine

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

COVID-19MalariaPlasmodium Falciparum MalariaPlasmodium Vivax Malaria

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

1

Artesunate-amodiaquine

Sanofi

Phase 3

12

Aldactone

Pfizer

Preclinical

13

Tricor

JJagotec

Preclinical

14

Rayaldee

OOrganon and Co

Preclinical

15

Statin

Bristol-Myers Squibb

Preclinical

16

Statins

Sanofi

Preclinical

17

Aprotinin

Bayer

Preclinical

18

Olokizumab

UCB

Preclinical

19

Hymecromone

SStanford University

Preclinical

110

Opaganib

RRedHill Biopharma Limited

Preclinical

1Show 10 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Malaria19 trials

Safe and Efficacious Artemisinin-based Combination Treatments for African Pregnant Women With Malaria

Completed·IInstitute of Tropical Medicine, Belgium·Phase 3·NCT00852423·3,428 enrolled

Artemisinin-Based Antimalarial Combinations and Clinical Response in Cameroon

Completed·UUniversity of Yaounde 1·Phase 3·NCT01845701·720 enrolled

Effectiveness and Safety of Intermittent Preventive Treatment for Malaria Using Either Dihydroartemisinin-piperaquine or Artesunate-amodiaquine in Reducing Malaria Related Morbidities and Improving Cognitive Ability in School-aged Children in Tanzania

Completed·NNational Institute for Medical Research, Tanzania·Phase 3·NCT03640403·1,555 enrolled

Show 16 more trials

Test Efficacy Study on the Recommended Antimalarial Drugs in the Democratic Republic of the Congo

Completed·MMinistry of Public Health, Democratic Republic of the Congo·Phase 4·NCT06076213·1,260 enrolled

Efficacy of Three ACTs for the Treatment of Falciparum Malaria in Maradi Niger

Completed·EEpicentre·Phase 4·NCT01755559·663 enrolled

Kintampo Trial of Combination Therapy for Malaria

Completed·LLondon School of Hygiene and Tropical Medicine·Phase 4·NCT00119145·510 enrolled

Effectiveness of Intermittent Preventive Treatment for Malaria in Children

Completed·LLondon School of Hygiene and Tropical Medicine·Phase 2/3·NCT00119132·2,602 enrolled

Amodiaquine+Artesunate for Uncomplicated Malaria Treatment

Completed·CCentre Muraz·Phase 4·NCT01213433·150 enrolled

Safety and Efficacy of Methylene Blue Combined With Amodiaquine or Artesunate for Malaria Treatment in Children of Burkina Faso

Completed·HHeidelberg University·Phase 2·NCT00545935·186 enrolled

Health Systems Implementation and Molecular Surveillance of Multiple First-Line Treatments for Uncomplicated Malaria in Western Kenya

Completed·SStrathmore University··NCT07362498·316 enrolled

A Study to Find Out if a Combination of 3 Medicines for the Treatment of Malaria Works as Well and is as Safe and Tolerable as Combinations of 2 Medicines

Recruiting·UUniversity of Oxford·Phase 3·NCT05951595·1,680 enrolled

OPTImizing Malaria And HIV Treatment in a Shifting Landscape in Africa

Recruiting·YYale University·Phase 4·NCT06967519·380 enrolled

In Vivo Efficacy of Artemether-Lumefantrine and Artesunate-Amodiaquine for Uncomplicated P. Falciparum Malaria

Completed·CCenters for Disease Control and Prevention·Phase 4·NCT02637128·452 enrolled

Artesunate Plus Amodiaquine in Malaria in Cote d'Ivoire

Completed·Sanofi·Phase 4·NCT01023399·580 enrolled

Artemether-lumefantrine (AL) Versus Artesunate + Amodiaquine (ASAQ) for the Treatment of Uncomplicated Falciparum Malaria in Burkina Faso

Completed·CCentre Muraz·Phase 4·NCT01017770·340 enrolled

Efficacy and Safety of ASAQ and PD for the Treatment of Uncomplicated Falciparum Malaria in Mainland Tanzania

Completed·NNational Institute for Medical Research, Tanzania·Phase 4·NCT03431714·333 enrolled

Safety and Efficacy of Recommended Antimalarial in the Democratic Republic of the Congo

Completed·MMinistry of Public Health, Democratic Republic of the Congo·Phase 4·NCT04618523·1,117 enrolled

Efficacy of Artesunate + Amodiaquine Versus Artemether-lumefantrine for Falciparum Malaria in Zanzibar, 2005

Completed·PProfessor Anders Björkman·Phase 4·NCT03768908·359 enrolled

In Vivo and in Vitro Efficacy of Antimalarial Treatments in Children in Burkina Faso

Completed·CCentre Muraz·Phase 4·NCT00808951·440 enrolled

Plasmodium vivax malaria1 trial

Efficacy and Tolerability of Artesunate Amodiaquine Versus Chloroquine in the Treatment of Uncomplicated Plasmodium Vivax Malaria

Completed·Sanofi·Phase 3·NCT01378286·380 enrolled

COVID-191 trial

Four Different Experimental Drug Regimens to Standard of Care for the Treatment of Symptomatic Outpatients With COVID-19

Completed·SShin Poong Pharmaceutical Co. Ltd.·Phase 2·NCT04532931·192 enrolled

ART1 trial

Bioavailability of the Fixed Combination of Amodiaquine and Artesunate Under Fed & Fasted Conditions

Completed·Sanofi·Phase 1·NCT00386503·22 enrolled

Efficacy1 trial

Efficacy of Artesunate + Amodiaquine Four Years After Its Introduction in Zanzibar

Suspended·KKarolinska University Hospital·Phase 4·NCT00465257·110 enrolled

4 more indications

Pregnancy1 trial

Efficacy,Safety and Tolerability of Dihydroartemisinin-Piperaquine for Uncomplicated Malaria in Pregnancy in Ghana

Completed·KKwame Nkrumah University of Science and Technology·Phase 3·NCT01231113·417 enrolled

Plasmodium falciparum malaria1 trial

ATAQ EASY: Artesunate + Amodiaquine Fixed Dose Combination in the Treatment of Uncomplicated Plasmodium Falciparum Malaria

Completed·Sanofi·Phase 3·NCT00316329·1,032 enrolled

Interaction1 trial

Dolutegravir Interactions With Artemisinin-based Combination Therapies

Completed·UUniversity of Liverpool·Phase 1·NCT02242799·46 enrolled

Efficacy and Safety1 trial

Efficacy and Safety of Artemisinin-based Combination Treatments in the Democratic Republic of the Congo

Completed·MMinistry of Public Health, Democratic Republic of the Congo·Phase 4·NCT02940756·1,615 enrolled

Details

Drug Info

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