Centanafadine

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Major Depressive DisorderAnxietySmoking CessationEating Disorder

386 competitors in Major Depressive Disorder

#DrugCompanyPhaseTrials

1

Crestor

AstraZeneca

Phase 3

12

Fetzima

AbbVie

Phase 3

93

Bupropion XL

GSK

Phase 3

14

Venlafaxine ER

Pfizer

Phase 3

25

Seltorexant

Johnson & Johnson

Phase 3

56

Rapastinel

AbbVie

Phase 3

107

TC-5214

AstraZeneca

Phase 3

68

Centanafadine

Otsuka

Phase 3

19

SR58611A

Sanofi

Phase 3

410

NMRA-335140

NNeumora Therapeutics, Inc.

Phase 3

4Show 35 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Attention Deficit Hyperactivity Disorder5 trials

A Trial of Centanafadine Long-term Safety in Children and Adolescents With Attention-deficit/Hyperactivity Disorder.

Active, not recruiting·Otsuka·Phase 3·NCT05279313·680 enrolled

A Trial Evaluating the Efficacy, Safety, & Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder

Completed·Otsuka·Phase 3·NCT03605680·604 enrolled

A Trial to Evaluate the Efficacy, Safety, and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-deficit/Hyperactivity Disorder

Completed·Otsuka·Phase 3·NCT03605836·590 enrolled

Show 2 more trials

A Trial Evaluating the Long-term Safety and Tolerability of Centanafadine Sustained-release Tablets in Adults With Attention-Deficit/Hyperactivity Disorder

Completed·Otsuka·Phase 3·NCT03605849·662 enrolled

A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine in Pediatric Subjects With Attention-deficit/Hyperactivity Disorder

Completed·Otsuka·Phase 1·NCT04398225·32 enrolled

Trial3 trials

Trial to Demonstrate the Equivalence of Two Different Strengths of Oral Centanafadine Capsules in Healthy Subjects

Completed·Otsuka·Phase 1·NCT07486895·44 enrolled

A Trial to Assess How Centanafadine Interacts With Stimulants in the Body

Recruiting·Otsuka·Phase 1·NCT07314333·42 enrolled

A Trial to Compare the Amount of Centanafadine That Enters the Bloodstream for Two Different Formulations of Centanafadine

Completed·Otsuka·Phase 1·NCT07465731·62 enrolled

Efficacy and Safety2 trials

A Trial of Centanafadine Efficacy and Safety in Children With Attention-deficit/ Hyperactivity Disorder (ADHD)

Completed·Otsuka·Phase 3·NCT05428033·574 enrolled

A Trial of Centanafadine Efficacy and Safety in Adolescents With Attention- Deficit/Hyperactivity Disorder

Completed·Otsuka·Phase 3·NCT05257265·459 enrolled

Pediatric1 trial

A Trial to Assess the Pharmacokinetics, Safety, and Tolerability of Centanafadine Capsules in Pediatric Subjects With Attention-deficit Hyperactivity Disorder

Completed·Otsuka·Phase 1·NCT04786730·50 enrolled

Attention Deficit Hyperactivity Disorder (ADHD)1 trial

Open-label, Single-dose Trial to Assess the Pharmacokinetics of Centanafadine Extended-release Capsules in Pediatric Participants With Attention-deficit Hyperactivity Disorder (ADHD)

Completed·Otsuka·Phase 2·NCT04081363·13 enrolled

4 more indications

Smoking Cessation1 trial

Efficacy of Centanafadine SR as a Potential Smoking Cessation Treatment

Completed·Otsuka·Phase 2·NCT05066724·50 enrolled

Eating Disorder1 trial

A Trial of Centanafadine Efficacy, Safety, and Tolerability in Adult Subjects With Binge Eating Disorder

Completed·Otsuka·Phase 2·NCT05113953·147 enrolled

Major Depressive Disorder1 trial

Trial of Centanafadine Efficacy and Safety as Monotherapy or as Adjunct to SSRI in Adults With Major Depressive Disorder

Completed·Otsuka·Phase 2·NCT05536414·337 enrolled

Anxiety1 trial

P3b Short-term Study of CTN in Patients With ADHD and Comorbid Anxiety

Recruiting·Otsuka·Phase 3·NCT06973577·308 enrolled

Details

Drug Info

Related News