Dimenhydrinate

ApprovedSmall molecule

SSt. Justine's Hospital

Dimenhydrinate is one of 62 small molecule programs targeting Vertigo. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

VertigoActive, not recruiting

GastroenteritisActive, not recruiting

Nausea and VomitingActive, not recruiting

VertigoApproved

Active, not recruiting

GastroenteritisApproved

Active, not recruiting

Nausea and VomitingPreclinical

Active, not recruiting

Competition

Competitive Landscape

224 competitors in Nausea and Vomiting

#DrugCompanyPhaseTrials

Dimenhydrinate

SSt. Justine's Hospital

Approved

2 2

Aloxi

AAvyxa

Preclinical

27 3

Alfenta

Alnylam Pharmaceuticals

Preclinical

1 4

Ramosetron

Astellas

Preclinical

15 5

Phenergan

BBassett Healthcare

Preclinical

5 6

MS Contin

HHikma Pharmaceuticals LLC

Preclinical

3 7

Haldol

DDePuy Orthopaedics

Preclinical

3 8

Adriamycin

GGynecologic Oncology Group

Preclinical

2 9

Cytoxan

BBaxter Healthcare Corporation

Preclinical

2 10

Anerem

AAcacia Pharma Ltd

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Nausea and vomiting2 trials

Prophylactic Dimenhydrinate for Intraoperative Nausea and Vomiting

Completed·SSamuel Lunenfeld Research Institute, Mount Sinai Hospital·N/A·NCT00791960·149 enrolled

The Effect of Dimenhydrinate on Postoperative Nausea and Vomiting After Abdominal Hysterectomy: Randomized-controlled Trial

Not yet recruiting·PPreeyaporn Jirakittidul·N/A·NCT06395064·160 enrolled

Vertigo2 trials

Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin

Completed·AApsen Farmaceutica S.A.·Phase 3·NCT02112578·292 enrolled

Comparison of Efficacy Dimenhydrinate and Metoclopramide in the Treatment of Nausea Due to Vertigo

Completed·PPamukkale University·Phase 4·NCT02253524·200 enrolled

Gastroenteritis1 trial

A Trial Comparing the Effect of Oral Dimenhydrinate Versus Placebo in Children With Gastroenteritis

Completed·SSt. Justine's Hospital·Phase 4·NCT00124787·150 enrolled

Ondansetron1 trial

Dimenydrinate vs Ondansetron for PONV (DONV)

Completed·UUniversity of Thessaly·N/A·NCT05590936·190 enrolled

Vomiting1 trial

Prevention Post Operative Nausea Vomiting in Ambulatory Gynecologic Laparoscopy

Completed·PPrince of Songkla University·Phase 2·NCT01543945·340 enrolled

1 more indication

Enhanced Recovery1 trial

Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data

Completed·JJennifer Holder-Murray·Phase 3·NCT04606264·2,977 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Dimenhydrinate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Dimenhydrinate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Dimenhydrinate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — St. Justine's Hospital company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: SSt. Justine's Hospital

Dimenhydrinate

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Nausea and vomiting2 trials

Vertigo2 trials

Gastroenteritis1 trial

Ondansetron1 trial

Vomiting1 trial

Enhanced Recovery1 trial

References

Drug Info

Quick Facts

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