diphenhydramine HCl

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

HIV-1 InfectionUrticariaHemodynamic

66 competitors in HIV-1 Infection

#DrugCompanyPhaseTrials

1

Venclexta

AbbVie

Approved

12

Vemlidy

Gilead

Approved

—3

Taxol

Teva

Approved

—4

Niacor

AbbVie

Approved

—5

Epidiolex

Jazz Pharmaceuticals

Approved

—6

Bayer Aspirin

Bayer

Approved

—7

Crestor

AstraZeneca

Approved

—8

Ziagen

GSK

Approved

—9

Oncovin

Eli Lilly

Approved

—10

Emtriva

Gilead

Approved

—Show 43 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Papilloma1 trial

E7 TCR T Cells for Human Papillomavirus-Associated Cancers

Completed·NNational Cancer Institute (NCI)·Phase 1/2·NCT02858310·224 enrolled

Orthostatic Hypotension1 trial

Treatment of Orthostatic Hypotension in Autonomic Failure

Completed·VVanderbilt University·Phase 1·NCT00223691·389 enrolled

Systemic Lupus Erythematosus1 trial

A Study to Evaluate the Efficacy and Safety of Obinutuzumab in Participants With Systemic Lupus Erythematosus

Active, not recruiting·Roche·Phase 3·NCT04963296·303 enrolled

Idiopathic Nephrotic Syndrome1 trial

A Study to Evaluate the Efficacy and Safety of Obinutuzumab Versus MMF in Participants With Childhood Onset Idiopathic Nephrotic Syndrome

Active, not recruiting·Roche·Phase 3·NCT05627557·85 enrolled

Oral1 trial

Bioequivalence Between Two Oral Formulations of Diphenhydramine Hydrochloride

Completed·JJohnson & Johnson Consumer and Personal Products Worldwide·Phase 1·NCT00662337·36 enrolled

9 more indications

Urticaria1 trial

Phase III Clinical Study of Cetirizine Hydrochloride Injection in Treatment of Acute Urticaria

Recruiting·SShandong New Time Pharmaceutical Co., LTD·Phase 3·NCT06819774·284 enrolled

HIV-1 infection1 trial

Controlled Clinical Trial of Antiviral Cytotoxic T Lymphocyte (CTL) Infusion Following Combination Antiretroviral Drug Therapy for Asymptomatic HIV-1 Infection

Terminated·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000875·16 enrolled

Locally-advanced Rectal Cancer1 trial

A Phase 1-2 Trial of Cetuximab in Combination With Oxaliplatin, Capecitabine, and Radiation Therapy Followed by Surgery for Locally-advanced Rectal Cancer

Terminated·GGeorge Albert Fisher·Phase 1/2·NCT00226941·23 enrolled

Sleep1 trial

Evaluation of Diphenhydramine Hydrochloride Effects in Subjects With Occasional Sleeplessness

Completed·PProcter and Gamble·Phase 4·NCT02578186·33 enrolled

Adolescent1 trial

Study to Evaluate Diphenhydramine in Children and Adolescents

Completed·JJohnson & Johnson Consumer and Personal Products Worldwide·Phase 1·NCT00762749·36 enrolled

Hemodynamic1 trial

Histamines and Central Hemodynamics

Recruiting·UUniversity of British Columbia·N/A·NCT07285031·20 enrolled

MPA1 trial

Compare Pharmacokinetic (PK) Profiles of Naproxen Sodium, Diphenhydramine Hydrochloride, and Naproxen Sodium and Diphenhydramine Hydrochloride Combination

Completed·Bayer·Phase 1·NCT01666678·32 enrolled

Lupus Nephritis1 trial

A Phase II, Randomized, Double-Blind, Placebo-Controlled, Multicenter Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of Obinutuzumab in Adolescent Patients With Active Class III or IV Lupus Nephritis, Including an Evaluation of Open Label Safety and PK in a Cohort of Pediatric Patients (Aged 5 to < 12)

Recruiting·Roche·Phase 2·NCT05039619·40 enrolled

Unspecified1 trial

Lorazepam, Diphenhydramine Hydrochloride, and Haloperidol Gel in Healthy Volunteers

Completed·VVirginia Commonwealth University·N/A·NCT01204255·11 enrolled

Details

Drug Info

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