Gonal-f
(Follitropin alfa)PreclinicalSmall molecule
EMD SeronoFollitropin alfa is a fertility medication that helps stimulate the ovaries in women to produce eggs, and is also used to stimulate sperm production in men with certain fertility problems.[1] Gonal-f is currently being investigated across 5 indications[3], with its most advanced program in Preclinical.[1]
Gonal-f is one of 62 small molecule programs targeting Female Infertility. It is currently in Preclinical.
5
Indications
31
Total Trials
3
Active Trials
61
Competitors
1
FDA Application
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[3][1]
Indication
Competition
Competitive Landscape
46 competitors in Pregnancy
#DrugCompanyPhaseTrials
1Femara
NovartisApproved
Bayer Aspirin
BayerApproved
Marinol
Jazz PharmaceuticalsApproved
Rayos
RRoxane Laboratories
Approved
Pifeltro
CCidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)
Approved
BEYFORTUS
SanofiPhase 3
Dihydroartemisinin-Piperaquine
GSKPhase 3
Monoferric
PPharmacosmos A/S
Phase 3
Cimzia
UCBPhase 2
Sulfadoxine Pyrimethamine
PfizerPhase 3
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Controlled Ovarian Stimulation5 trials
Efficacy and Safety4 trials
Infertility4 trials
Show 1 more trial
Trial2 trials
10 more indications
Ovarian Stimulation2 trials
Intracytoplasmic Sperm Injection2 trials
Women2 trials
Gene Expression1 trial
Observational Study1 trial
Frozen Embryo Transfer1 trial
Estradiol and Progesterone Levels Following Frozen Embryo Transfer
Completed·—·Phase 4·NCT04997525·305 enrolled
Infertility (IVF Patients)1 trial
Regulatory
FDA Approval Timeline[4]
Sep 29, 1997
GONAL-F
BLA BLA020378
Sources
References
- [1]
- [2]
- [3]Open Targets Platform — Drug–disease associations for Follitropin alfa. EMBL-EBI & Wellcome Sanger Institute.
- [4]
- [5]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Follicle Stimulating Hormone Receptor Agonist[2]
- Modality
- Small molecule[2]
- Highest Phase
- Preclinical[1]
- Company