Foscavir
(Foscarnet sodium)ApprovedSmall molecule
Foscarnet sodium is used to treat serious viral infections, particularly cytomegalovirus (CMV) infections in people with weakened immune systems, and herpes simplex virus infections that don't respond to other treatments.[2] Foscavir is currently approved and in use across 11 indications[4].[1]
Foscavir is one of 192 small molecule programs targeting HIV infection. It is currently in Approved.
11
Indications
24
Total Trials
1
Active Trials
191
Competitors
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
547 competitors in Pneumonia
#DrugCompanyPhaseTrials
1Foscavir
NNational Institute of Allergy and Infectious Diseases (NIAID)
Approved
Primaxin
PfizerPreclinical
Jakafi
IncytePreclinical
Acanya
PfizerPreclinical
Virazole
CConrado Roberto Hoffmann Filho
Preclinical
Gantanol
CConrado Roberto Hoffmann Filho
Preclinical
Primsol
CConrado Roberto Hoffmann Filho
Preclinical
Pepcid
KKenvue Brands
Preclinical
Aciphex
Akero TherapeuticsPreclinical
Protonix
WWyeth-Lederle Vaccines
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Timeline
Expected Milestones
Clinical
Trials by Indication[1]
Treatment6 trials
Show 3 more trials
CMV Retinitis Retreatment Trial
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000766·300 enrolled
Comparison of Two Methods in the Treatment of Cytomegalovirus of the Eyes in Patients With AIDS
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00001061·167 enrolled
Cytomegalovirus (CMV)3 trials
Immunodeficiency3 trials
Foscarnet Treatment of Serious CMV Retinitis Infection in Patients With Acquired Immunodeficiency Syndrome
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00000726·53 enrolled
Scar2 trials
The Effect of Stomach Acid on Foscarnet
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00000964·6 enrolled
Herpes Simplex Virus1 trial
9 more indications
Cytomegalovirus Infection1 trial
HIV infection1 trial
A Study of Foscarnet in the Treatment of HIV Infection in Patients Who Have Taken Zidovudine for a Long Time
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT00001002·12 enrolled
Intravenous1 trial
Myelosuppression1 trial
A Phase II Dose-Ranging, Open-Labelled Trial of Foscarnet Salvage Therapy for AIDS Patients With Sight-Threatening CMV Retinitis Who Cannot Be Treated With Ganciclovir Due To Myelosuppression or Treatment Failure
Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 2·NCT00000691·156 enrolled
Gastrointestinal1 trial
Cytomegalovirus (CMV) Infection1 trial
Infection Prophylaxis and Management in Treating Cytomegalovirus (CMV) Infection in Patients With Hematologic Malignancies Previously Treated With Donor Stem Cell Transplant
Active, not recruiting·—··NCT01199562·153 enrolled
Complication1 trial
Herpes Zoster1 trial
Safety and Efficacy1 trial
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Foscavir drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Foscarnet sodium. EMBL-EBI & Wellcome Sanger Institute.
- [5]
Details