Glucophage

Pipeline

Status by Indication[3][1]

Competition

Competitive Landscape

Type 2 DiabetesType 2 Diabetes MellitusAlcoholic Fatty Liver Disease

885 competitors in Type 2 Diabetes

#DrugCompanyPhaseTrials

1

Glucophage

AstraZeneca

Approved

12

Byetta

AstraZeneca

Preclinical

553

Jardiance

Boehringer Ingelheim

Preclinical

314

NOVOLIN R

Novo Nordisk

Preclinical

55

Cysteine Hydrochloride

Novartis

Preclinical

16

Nexium

DDexcel Pharma Technologies Ltd.

Preclinical

17

Inderal

WWyeth-Lederle Vaccines

Preclinical

18

Pravachol

KKaruna Therapeutics, Inc., a Bristol Myers Squibb company

Preclinical

19

Cecon

MMcGuff Pharmaceuticals, Inc.

Preclinical

110

Forxiga

AstraZeneca

Preclinical

3Show 21 more competitors

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Clinical

Trials by Indication[1]

Metformin5 trials

Bioequivalence Study of Metformin 1000 mg Tablets Immediate Release (IR) Versus Glucophage® 1000 mg Tablets IR In Healthy Subjects

Completed·GGeropharm·Phase 1·NCT03458208·18 enrolled

Bioequivalence Study for Acarbose/Metformin FDC

Completed·Bayer·Phase 1·NCT04065581·24 enrolled

Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fed Condition

Completed·—·Phase 1·NCT01160068·50 enrolled

Show 2 more trials

BE Study of Metformin GSK 500mg

Completed·GSK·Phase 2·NCT01710527·32 enrolled

Bioequivalence Study of Metformin Hydrochloride Tablets 1000 mg Tablets of Dr. Reddy's Laboratories Limited Under Fasting Condition

Completed·—·Phase 1·NCT01160042·54 enrolled

Dapagliflozin1 trial

Bioavailability Study of Fixed Dose Combination (FDC) Formulations of Dapagliflozin and Metformin XR Versus Individual Component Coadministered to Healthy Subjects in a Fasted State

Completed·AstraZeneca·Phase 1·NCT01002807·15 enrolled

Type 2 Diabetes1 trial

Response of Gut Microbiota in Type 2 Diabetes to Hypoglycemic Agents

Unknown status·PPeking Union Medical College Hospital·Phase 4·NCT04287387·180 enrolled

Treatment1 trial

Myoinositol Treatment and Asprosin Levels in PCOS

Completed·NNear East University, Turkey·N/A·NCT05951309·30 enrolled

Fasting Conditions1 trial

A Relative Bioavailability Study of Metformin HCL Tablets, 1000 mg Under Fasting Conditions

Completed·Novartis·Phase 1·NCT00865033·32 enrolled

5 more indications

Endothelial Function1 trial

Evaluate the Effect of Exenatide Treatment on Coronary Artery Endothelial Function

Unknown status·—·Phase 4·NCT02584075·100 enrolled

Clinical Trial1 trial

Clinical Trial to Compare the Pharmacokinetics and Pharmacodynamics After Oral Administration of Glucophage and HL-018

Completed·—·Phase 1·NCT01232036·28 enrolled

Type 2 Diabetes Mellitus1 trial

Metformin Hydrochloride Sustained-release Tablets (Ⅲ) in Patients With Type 2 Diabetes Mellitus Complicated With Coronary Heart Disease

Recruiting·CChina National Center for Cardiovascular Diseases·Phase 4·NCT06932874·356 enrolled

Alcoholic Fatty Liver Disease1 trial

Metformin for the Treatment of Nonalcoholic Fatty Liver Disease (NAFLD)

Terminated·—·Phase 4·NCT00736385·11 enrolled

Diabetes, Type 21 trial

Evaluate Adherence to Treatment With Glucophage Sachets Versus Tablets in Diabetes Type 2 Patients Previously Treated With Metformin Tablets

Withdrawn·Merck & Co.·Phase 4·NCT01510522

Details

Drug Info

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