Human albumin

PreclinicalSmall molecule

TTonghua Anrate Biopharmaceutical Co., Ltd.

Human albumin is one of 43 small molecule programs targeting Gastric Cancer. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Gastric CancerActive, not recruiting

Ovarian Hyperstimulation SyndromeActive, not recruiting

Gastric CancerPreclinical

Active, not recruiting

Ovarian Hyperstimulation SyndromePreclinical

Active, not recruiting

Competition

Competitive Landscape

193 competitors in Gastric Cancer

#DrugCompanyPhaseTrials

Platinol

MMcNeil Consumer & Specialty Pharmaceuticals, a Division of McNeil-PPC, Inc.

Phase 3

55 2

Taxotere

AAvyxa

Phase 3

45 3

Avastin

Roche

Phase 3

11 4

Cyramza

Eli Lilly

Phase 3

10 5

Tyvyt

Innovent Biologics (Suzhou) Co. Ltd.

Phase 3

20 6

Tuoyi

SSun Yat-sen University

Phase 3

18 7

Yervoy

Bristol-Myers Squibb

Phase 3

5 8

S-1

Taiho Oncology, Inc.

Phase 3

45 9

Apatinib

LLaNova Medicines Zhejiang Co., Ltd.

Phase 3

35 10

Tuoyi

CCoherus Oncology, Inc.

Phase 3

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

Phase 2Recruiting

Liver Cirrhosis

NCT05895136

Post-ApprovalNot yet recruiting

Preeclampsia

NCT06107335

Phase 3Recruiting

Heart Failure

NCT06630923

Q3 2027

N/ARecruiting

Subarachnoid Hemorrhage

NCT06548477

Q3 2028

Phase 3Not yet recruiting

Stiff-Person Syndrome

NCT07552987

Clinical

Trials by Indication[1]

Subarachnoid Hemorrhage2 trials

Human Albumin for Clinical Outcome in Aneurysmal Subarachnoid Hemorrhages

Recruiting·HHamad Medical Corporation·N/A·NCT06548477·84 enrolled

Treatment of Subarachnoid Hemorrhage With Human Albumin

Terminated·—·Phase 1·NCT01747408·47 enrolled

Hypoalbuminemia2 trials

The Therapeutic Role of Intravenous Albumin Administration for Peptic Ulcer Bleeding Patients With Hypoalbuminemia

Completed·NNational Cheng-Kung University Hospital·Phase 4·NCT01822600·91 enrolled

A Study of Recombinant Human Albumin Injection to Treat Hypoalbuminemia in Cirrhotic Patients With Ascites

Completed·TTonghua Anrate Biopharmaceutical Co., Ltd.·Phase 3·NCT06911554·416 enrolled

Peritonitis2 trials

Clinical, Inflammatory, and Economic Impact of Dextran 70 in Treating Spontaneous Bacterial Peritonitis

Terminated·UUniversity of Virginia·Phase 4·NCT00570960·8 enrolled

Albumin Administration in Patients With Cirrhosis and Infections Unrelated to Spontaneous Bacterial Peritonitis

Completed·HHospital Clinic of Barcelona·Phase 3·NCT00124228·110 enrolled

After Cardiac Surgery1 trial

Endothelial Function After Cardiac Surgery

Completed·TThe Cleveland Clinic·N/A·NCT02882074·85 enrolled

Cardiac Surgery1 trial

Influence of Albumin on Acute Renal Dysfunction Associated With Cardiac Surgery Under Extracorporeal Circulation

Unknown status·FFundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau·Phase 4·NCT03373318·250 enrolled

21 more indications

Septic Shock1 trial

Human Albumin Treatment in Adult Septic Shock. A Study Evaluating Immune Response and Organ Failure.

Withdrawn·AAlbimmune SL·Phase 2·NCT05645887

Systemic Inflammatory Response Syndrome1 trial

Albumin Administration in Cirrhotic Patients With Bacterial Infection and a Systemic Inflammatory Response Syndrome Unrelated to Spontaneous Bacterial Peritonitis

Terminated·—·Phase 3·NCT01359813·193 enrolled

Pancreaticoduodenectomy1 trial

Intravenous Human Albumin In Improving Pancreaticoduodenectomy Outcomes

Unknown status·UUniversiti Kebangsaan Malaysia Medical Centre·Phase 2·NCT04418739·122 enrolled

Cirrhosis1 trial

Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and Ascites

Recruiting·AAleksander Krag·Phase 3·NCT05056220·240 enrolled

Preeclampsia1 trial

Effect of Albumin Versus Routine Care on Hemodynamic Response and Stability in Patients With Preeclampsia Guided by a Non-invasive Hemodynamic Monitoring System During Cesarean Delivery With Spinal Anesthesia

Not yet recruiting·TThe University of Texas Health Science Center, Houston·Phase 4·NCT06107335·62 enrolled

Tolerance1 trial

Safety and Tolerance Study of Recombinant Human Albumin Injection in Healthy Subjects.

Completed·TThe First Hospital of Jilin University·Phase 1·NCT04641364·80 enrolled

Prednisolone1 trial

Intravenous Immunoglobulin and Prednisolone for RPL After ART.

Completed·—·Phase 2·NCT04701034·80 enrolled

Ovarian Hyperstimulation Syndrome1 trial

The Effect of Human Albumin Infusion on VEGF Levels in Women at Risk for Ovarian Hyperstimulation Syndrome

Withdrawn·YYale University·N/A·NCT00617864

Polyneuropathy1 trial

The Impact of IVIG Treatment on Critical Illness Polyneuropathy and/or Myopathy in Patients With MOF and SIRS/Sepsis

Terminated·MMedical University of Vienna·Phase 1·NCT01867645·38 enrolled

Sepsis1 trial

Feasibility of 5% Albumin Compared With Balanced Crystalloid, as Intravenous Fluid Resuscitation in Adult Patients With Sepsis, Presenting as an Emergency to Hospital

Completed·UUniversity of Edinburgh·Phase 3·NCT04540094·300 enrolled

Encephalopathy1 trial

Albumin Infusion Effects in Mortality in Patients With Cirrhosis and Hepatic Encephalopathy

Unknown status·HHospital Universitari Vall d'Hebron Research Institute·Phase 4·NCT02401490·128 enrolled

Propofol1 trial

Agitated Saline, Albumin, or Propofol-albumin Mixture for Enhanced Contrast in TEE Examinations

Completed·UUniversity of California, San Diego·N/A·NCT02613052·17 enrolled

Infusion1 trial

Effect of Albumin Infusion on Oxidative Albumin Modification, Albumin Binding Capacity and Plasma Thiol Status

Completed·MMedical University of Graz··NCT03214796·40 enrolled

Gastric Cancer1 trial

Human Albumin and Anastomotic Leakage After Gastric Cancer Surgery

Completed·RRuijin Hospital··NCT04490668·1,049 enrolled

Miscarriage1 trial

Trial of the Efficacy of Intravenous Immunoglobulin for Treating Women With Unexplained Secondary Recurrent Miscarriage

Completed·RRigshospitalet, Denmark·Phase 3·NCT00722475·82 enrolled

Heart Failure1 trial

PREVENTION OF WORSENING RENAL FUNCTION OF INTRAVENUS ALBUMIN IN HEART FAILURE PATIENTS

Recruiting·—·Phase 3·NCT06630923·250 enrolled

Phase II1 trial

Phase II/III of Recombinant Human Albumin Injection

Completed·TThe First Hospital of Jilin University·Phase 2·NCT06411743·90 enrolled

Stiff-Person syndrome1 trial

A Phase III, Randomized, Double-blind, Placebo-Controlled, Parallel Group, Multicenter Study to Assess the Efficacy and Safety of Intravenous Human Normal Immune Globulin (IGIV) 10% in Adult Patients With Stiff Person Syndrome

Not yet recruiting·KKedrion S.p.A.·Phase 3·NCT07552987·38 enrolled

Liver Cirrhosis1 trial

A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).

Recruiting·EEuropean Foundation for Study of Chronic Liver Failure·Phase 2·NCT05895136·90 enrolled

Supplementation1 trial

The Effect of Albumin Supplementation on the Inflammatory and Oxidative Stress Markers in Septic Patients

Completed·UUniversity of Pecs·Phase 1·NCT03950778·40 enrolled

Unspecified1 trial

SUbstition of PERioperative Albumin Deficiency Disorders

Completed·TTechnical University of Munich·Phase 4·NCT03167645·600 enrolled

Sources

References

[1]
ClinicalTrials.gov — 29 trial records for Human albumin. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Human albumin compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Human albumin. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Tonghua Anrate Biopharmaceutical Co., Ltd. company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: TTonghua Anrate Biopharmaceutical Co., Ltd.

Human albumin

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Q3 2027

Q3 2028

Trials by Indication[1]

Subarachnoid Hemorrhage2 trials

Hypoalbuminemia2 trials

Peritonitis2 trials

After Cardiac Surgery1 trial

Cardiac Surgery1 trial

Septic Shock1 trial

Systemic Inflammatory Response Syndrome1 trial

Pancreaticoduodenectomy1 trial

Cirrhosis1 trial

Preeclampsia1 trial

Tolerance1 trial

Prednisolone1 trial

Ovarian Hyperstimulation Syndrome1 trial

Polyneuropathy1 trial

Sepsis1 trial

Encephalopathy1 trial

Propofol1 trial

Infusion1 trial

Gastric Cancer1 trial

Miscarriage1 trial

Heart Failure1 trial

Phase II1 trial

Stiff-Person syndrome1 trial

Liver Cirrhosis1 trial

Supplementation1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

Related News