Morphine sulphate

Phase 3Small molecule

EEgalet Ltd

Indications

Total Trials

Active Trials

Competitors

Timeline

Expected Milestones

Q4 2029

ApprovedNot yet recruiting

Cough

NCT07288528

Phase 3Not yet recruiting

Analgesia

NCT06835504

Clinical

Trials by Indication[1]

Cancer Pain2 trials

An Interventional Study for Patient With Cancer Pain to Evaluate the Efficacy and Safety of OxyNorm® Compared to Morphine Sulfate Through the IV Continuous Infusion.

Completed·MMundipharma Korea Ltd·Phase 4·NCT02660229·66 enrolled

Efficacy and Safety Study of Nasalfent for Treatment of Breakthrough Cancer Pain in Patients Taking Regular Opioids

Completed·AArchimedes Development Ltd·Phase 3·NCT00589823·135 enrolled

Efficacy and Safety1 trial

A Efficacy and Safety Trial of Controlled Release (CR) Morphine in Cancer Patients

Completed·EEgalet Ltd·Phase 2·NCT00446069·36 enrolled

Analgesia1 trial

Morphine or Ketamine for Analgesia

Not yet recruiting·—·Phase 3·NCT06835504·1,010 enrolled

Immune Response1 trial

Effect of Morphine, Tramadol, and Ketorolac on Postoperative Stress and Immune Responses

Unknown status·—·Phase 2/3·NCT02449954·60 enrolled

Total Knee Replacement1 trial

Pain Treatment After Total Knee Replacement - Continuous Epidural Versus Intravenous Patient Controlled Analgesia With Morphine

Terminated·RRambam Health Care Campus·Phase 4·NCT00270322·80 enrolled

7 more indications

Efficacy1 trial

Efficacy of Multimodal Opioid Therapy During Hepatic Resection Surgery

Unknown status·SSt Vincent's University Hospital, Ireland·N/A·NCT00553553·45 enrolled

Single Dose1 trial

Effects of a Single Dose of Egalet® Morphine Combined With a Single Dose of Alcohol in Healthy Moderate Drinkers

Completed·EEgalet Ltd·Phase 1·NCT00802308·24 enrolled

Obstructive Sleep Apnoea1 trial

Morphine in Moderate Obstructive Sleep Apnoea

Terminated·PPapworth Hospital NHS Foundation Trust·Phase 3·NCT03127800·6 enrolled

Intravenous1 trial

Intranasal Fentanyl Versus Intravenous Morphine in the Treatment of Severe Painful Sickle Cell Crises in Children

Completed·UUniversity College Dublin·Phase 4·NCT03682211·31 enrolled

Treatment1 trial

A Study to Evaluate Tapentadol (CG5503) in the Treatment of Chronic Tumor-Related Pain Compared With Placebo and Morphine

Completed·GGrünenthal GmbH·Phase 3·NCT00472303·622 enrolled

Gastric Bypass Surgery1 trial

Intraoperative Lidocaine Infusion as a Sole Analgesic Versus Morphine in Laparoscopic Gastric Bypass Surgery

Completed·—·Phase 1·NCT05150756·60 enrolled

Cough1 trial

A 2x2 Factorial, Randomized, Open-label Trial to Evaluate Neuromodulators and Cough Control Therapy in Patients With Refractory or Unexplained Chronic Cough (FORTITUDE)

Not yet recruiting·MMcMaster University·Approved·NCT07288528·124 enrolled

Sources

References

[1]
ClinicalTrials.gov — 13 trial records for Morphine sulphate. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Morphine sulphate compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Morphine sulphate. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Egalet Ltd company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: EEgalet Ltd