plasma

ApprovedBiologic

CSL Behring

plasma is one of 314 biologic programs targeting Plantar Fasciitis. It is currently in Approved.

Indications

Total Trials

Active Trials

313

Competitors

Pipeline

Status by Indication[3][1]

Indication

Plantar FasciitisActive, not recruiting

Endothelial DysfunctionActive, not recruiting

Liver TransplantActive, not recruiting

HemorrhageActive, not recruiting

PneumoniaActive, not recruiting

Infectious DiseaseActive, not recruiting

PancreatitisActive, not recruiting

Liver DiseaseActive, not recruiting

Septic ShockActive, not recruiting

COVID-19Active, not recruiting

Plantar FasciitisApproved

Active, not recruiting

Endothelial DysfunctionPreclinical

Active, not recruiting

Liver TransplantPreclinical

Active, not recruiting

HemorrhagePhase 2/Phase 3

Active, not recruiting

PneumoniaPhase 2

Active, not recruiting

Infectious DiseasePreclinical

Active, not recruiting

PancreatitisApproved

Active, not recruiting

Liver DiseasePhase 2

Active, not recruiting

Septic ShockPhase 2

Active, not recruiting

COVID-19Phase 2/Phase 3

Active, not recruiting

Showing 10 of 13 indications

Competition

Competitive Landscape

1931 competitors in COVID-19

#DrugCompanyPhaseTrials

plasma

CSL Behring

Approved

2 2

Spikevax

Moderna

Preclinical

21 3

Bnt162b2

BioNTech

Preclinical

29 4

COVID-19 Vaccine

Moderna

Preclinical

27 5

Biaxin

AbbVie

Preclinical

2 6

Stivarga

Bayer

Preclinical

1 7

Aimovig

Amgen

Preclinical

1 8

Aldactone

Pfizer

Preclinical

1 9

Nexavar

Bayer

Preclinical

1 10

Singulair

AstraZeneca

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q3 2029

Phase 3Not yet recruiting

Burn Injury

NCT07212998

Clinical

Trials by Indication[1]

SMA2 trials

The Safety of Autologous Lyophilized Plasma Versus Fresh Frozen Plasma in Healthy Volunteers

Completed·HHemCon Medical Technologies, Inc·Phase 1·NCT00968487·16 enrolled

A Clinical Study of Lyophilized Plasma in Patients on Warfarin

Withdrawn·HHemCon Medical Technologies, Inc·Phase 2·NCT01541098

Hemorrhage2 trials

Early Use of Cryoprecipitate With Major Hemorrhage Protocol (MHP) Activation

Completed·BBryan Cotton·Phase 3·NCT04704869·1,604 enrolled

Pre-Hospital Use of Plasma for Traumatic Hemorrhage

Withdrawn·VVirginia Commonwealth University·Phase 2/3·NCT02303964

COVID-192 trials

Convalescent Plasma for Patients With COVID-19: A Randomized, Single Blinded, Parallel, Controlled Clinical Study

Completed·—·Phase 2/3·NCT04332835·92 enrolled

Convalescent Plasma for Patients With COVID-19: A Pilot Study

Completed·—·Phase 2·NCT04332380·10 enrolled

West Nile fever1 trial

High-Titer Neutralizing Plasma for West Nile Fever in Hospitalized Patients

Recruiting·GGili Regev-Yochay MD·Phase 2·NCT07094724·37 enrolled

Endothelial Dysfunction1 trial

Characterization of Endothelial Dysfunction as a Function of Hyperaemia of the Brachial Artery During Cardiac Surgery

Unknown status·—··NCT02853682·28 enrolled

12 more indications

Pilot Study1 trial

Pilot Study to Compare Fresh Frozen Plasma With 24-Hour Plasma in Babies Up to Age Six Months

Withdrawn·UUniversity of Chicago·Phase 4·NCT02774317

Septic Shock1 trial

Resuscitation With Plasma in Surgical and Trauma Patients With Septic Shock

Terminated·TThe University of Texas Health Science Center, Houston·Phase 2·NCT03366220·16 enrolled

Pneumonia1 trial

Convalescent Plasma Compared to the Best Available Therapy for the Treatment of SARS-CoV-2 Pneumonia

Completed·HHospital Universitario Dr. Jose E. Gonzalez·Phase 2·NCT04358783·31 enrolled

Infectious Disease1 trial

Collection of Plasma From People Who Recovered From or Were Vaccinated to Emerging Infectious Diseases

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)··NCT02338986·10 enrolled

Cohort Study1 trial

An Observational Cohort Study to Investigate the Risk of Thromboembolic Events in Patients Receiving Kcentra® or Plasma to Reverse Vitamin K Antagonist (VKA) Therapy in the Setting of Acute Major Bleeding

Completed· CSL Behring logo

CSL Behring··NCT02319460·2,238 enrolled

Plantar Fasciitis1 trial

Treatment of Plantar Fasciitis With Injection af Platelet-rich Plasma Into the Origin of the Plantar Fascia

Unknown status·KKolding Sygehus·Phase 4·NCT01509274·90 enrolled

Osteoarthritis1 trial

Evaluation of Platelet Rich Plasma (PRP) for Knee Osteoarthritis

Unknown status·UUniversity of Sao Paulo·Phase 2·NCT03138317·60 enrolled

Liver Transplant1 trial

Evaluation of the Safety of Octaplas™ Versus Plasma in Patients Undergoing Orthotopic Liver Transplantation

Terminated· Octapharma logo

Octapharma··NCT02037373·43 enrolled

Pancreatitis1 trial

Aggressive Hydration With Lactated Ringer's Solution Versus Plasma Solution for the Prevention of Post ERCP Pancreatitis

Completed·DDo Hyun Park·Phase 4·NCT05832047·844 enrolled

Disease Progression1 trial

Plasmapheresis Versus Plasma Infusion from Young APOE3 Homozygotes Into MCI APOE4 Homozygotes to Slow Disease Progression

Completed·MMayo Clinic·Phase 1·NCT03887741·3 enrolled

Liver Disease1 trial

Clinical Study of Lyophilized Plasma in Patients With Liver Disease

Withdrawn·HHemCon Medical Technologies, Inc·Phase 2·NCT01547078

Burn Injury1 trial

Plasma Resuscitation Early for Evaluating Volume and Endotheliopathy of Thermal Injury (PREEVEnT) Trial

Not yet recruiting·JJason Sperry·Phase 3·NCT07212998·750 enrolled

Sources

References

[1]
ClinicalTrials.gov — 20 trial records for plasma. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — plasma compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for plasma. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — CSL Behring company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Biologic[2]
Highest Phase: Approved[1]
Company: CSL Behring

plasma

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q3 2029

Trials by Indication[1]

SMA2 trials

Hemorrhage2 trials

COVID-192 trials

West Nile fever1 trial

Endothelial Dysfunction1 trial

Pilot Study1 trial

Septic Shock1 trial

Pneumonia1 trial

Infectious Disease1 trial

Cohort Study1 trial

Plantar Fasciitis1 trial

Osteoarthritis1 trial

Liver Transplant1 trial

Pancreatitis1 trial

Disease Progression1 trial

Liver Disease1 trial

Burn Injury1 trial

References

Drug Info

Quick Facts

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