Sudafed
(Pseudoephedrine)ApprovedSmall molecule
Pseudoephedrine is used to relieve nasal congestion and sinus pressure caused by colds, allergies, or sinus infections. It works by narrowing blood vessels in the nasal passages to reduce swelling and help you breathe more easily.[2] Sudafed is currently approved and in use across 12 indications[4].[1]
Sudafed is one of 217 small molecule programs targeting Common Cold. It is currently in Approved.
12
Indications
20
Total Trials
0
Active Trials
216
Competitors
4
FDA Applications
NDA/BLA/ANDA regulatory filings
Pipeline
Status by Indication[4][1]
Indication
Showing 10 of 12 indications
Competition
Competitive Landscape
392 competitors in Obesity
#DrugCompanyPhaseTrials
1Sudafed
KKenvue Brands
Approved
Actemra
RochePreclinical
Avapro
SanofiPreclinical
Amidate
PfizerPreclinical
Colcrys
Alnylam PharmaceuticalsPreclinical
Cetrotide
EMD SeronoPreclinical
Minocin
TTriax
Preclinical
Firmagon
FerringPreclinical
Advil
KKenvue Brands
Preclinical
EGRIFTA WR
TTheratechnologies
Preclinical
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Clinical
Trials by Indication[1]
Allergic Rhinitis3 trials
An Efficacy Study of JNJ-39220675 and Pseudoephedrine in Participants With Allergic Rhinitis
Completed·
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.·Phase 2·NCT00804687·53 enrolled
Johnson & Johnson Pharmaceutical Research & Development, L.L.C.·Phase 2·NCT00804687·53 enrolledSeasonal Allergic Rhinitis3 trials
11 more indications
MPA1 trial
Medication1 trial
Blood Pressure Monitoring1 trial
Efficacy1 trial
Blood Pressure1 trial
Hyperbaric Oxygen Therapy1 trial
Nasal congestion1 trial
To Determine if Diphenhydramine Works for Nasal Congestion at Two Different Doses
Completed·JJohnson & Johnson Consumer and Personal Products Worldwide·Phase 4·NCT00648973·1,021 enrolled
Unspecified1 trial
TransMEM Gas Exchange -- Project 1, Aim 2
Completed·—·Phase 1·NCT01925729·84 enrolled
Regulatory
FDA Approval Timeline[5]
Jan 1, 1982
NOVAFED
NDA NDA017603
Jan 1, 1982
SUDAFED 12 HOUR
NDA NDA017941
Jan 1, 1982
AFRINOL
NDA NDA018191
Dec 15, 1992
SUDAFED 24 HOUR
NDA NDA020021
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Sudafed drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Pseudoephedrine. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]
Details
Drug Info
Quick Facts
- Mechanism of Action
- Norepinephrine Transporter Releasing Agent[3]
- Modality
- Small molecule[3]
- Highest Phase
- Approved[1]
- Company
- KKenvue Brands