Seroquel

ApprovedSmall molecule

AstraZeneca

Seroquel is one of 275 small molecule programs targeting Post-Traumatic Stress Disorder. It is currently in Approved.

Indications

Total Trials

Active Trials

274

Competitors

Pipeline

Status by Indication[3][1]

Indication

Post-Traumatic Stress DisorderActive, not recruiting

PsychosisActive, not recruiting

Alcohol DependenceActive, not recruiting

Social Anxiety DisorderActive, not recruiting

Major Depressive DisorderActive, not recruiting

SchizophreniaActive, not recruiting

Bipolar DisorderActive, not recruiting

DementiaActive, not recruiting

Post-Traumatic Stress DisorderPreclinical

Active, not recruiting

PsychosisApproved

Active, not recruiting

Alcohol DependencePhase 3

Active, not recruiting

Social Anxiety DisorderPhase 3

Active, not recruiting

Major Depressive DisorderPreclinical

Active, not recruiting

SchizophreniaPhase 3

Active, not recruiting

Bipolar DisorderPreclinical

Active, not recruiting

DementiaPhase 3

Active, not recruiting

Competition

Competitive Landscape

583 competitors in Schizophrenia

#DrugCompanyPhaseTrials

Seroquel

AstraZeneca

Approved

2 2

Zocor

OOrganon and Co

Preclinical

6 3

Depakote

Ibrance

Comtan

Orion Corporation, Orion Pharma

Preclinical

1 6

Rapamune

PPrism Pharmaceuticals

Preclinical

1 7

Persantine

Boehringer Ingelheim

Preclinical

1 8

Inversine

TTargacept Inc.

Preclinical

1 9

Luvox

SSolvay Pharmaceuticals

Preclinical

1 10

Permax

VValeant Pharmaceuticals

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Pilot Study2 trials

Psychotherapy for Bipolar II Depression, Pilot Study, Phase II

Completed·UUniversity of Pittsburgh·Phase 2/3·NCT00411463·25 enrolled

Quetiapine vs. Placebo in Alcohol Relapse Prevention - a Pilot Study

Completed·IInstitut fuer anwendungsorientierte Forschung und klinische Studien GmbH·Phase 2·NCT00561587·40 enrolled

Schizophrenia2 trials

SR-Registration Study 1, ROW: Efficacy and Safety of Seroquel® in the Treatment of Patients With Schizophrenia

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00206115·535 enrolled

Relapse Prevention, RoW: Study to Evaluate Prevention of Relapse in Patients in Stable Chronic Schizophrenia Receiving Either Seroquel or Placebo

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00228462·197 enrolled

Social Anxiety Disorder1 trial

Flushing in Social Anxiety Disorder on Seroquel

Completed·SSTART Clinic for Mood and Anxiety Disorders·Phase 3·NCT00773162·21 enrolled

Alcohol Dependence1 trial

Quetiapine Fumarate (Seroquel) for the Treatment of Alcohol Dependence.

Completed·UUniversity of Pennsylvania·Phase 3·NCT00124059·61 enrolled

Heavy Drinker1 trial

Seroquel for Frequent, Heavy Drinkers

Completed·UUniversity of Pennsylvania·Phase 2·NCT00674765·156 enrolled

8 more indications

Efficacy and Safety1 trial

Efficacy and Safety of Utapine vs. Seroquel in Patients With Bipolar Mania

Unknown status·TTaichung Veterans General Hospital·Phase 4·NCT01043679·40 enrolled

Major Depressive Disorder1 trial

Effect of Quetiapine on Sleep Architecture in Bipolar Depression and Major Depressive Disorder

Completed·QQueen's University··NCT00616889·15 enrolled

Bipolar Disorder1 trial

Effects of Quetiapine on Ultrastructural Hippocampal and Neurochemical Changes in Patients With Bipolar Disorder: Searching for Antidepressant and Mood Stabilising Neurophysiology

Completed·RRWTH Aachen University·N/A·NCT01552837·33 enrolled

Post-Traumatic Stress Disorder1 trial

Post-Traumatic Stress Disorder (PTSD) and Seroquel

Completed·CCambridge Health Alliance·N/A·NCT01066156·34 enrolled

Psychosis1 trial

Efficacy and Safety of Quetiapine in Treating Affective Symptoms of Patients With First-episode psychosis-a Pilot Study

Completed·IInstitut fuer anwendungsorientierte Forschung und klinische Studien GmbH·Phase 4·NCT00511277·60 enrolled

Safety and Efficacy1 trial

Safety and Efficacy Trial of the Use of Quetiapine Fumarate (SEROQUEL®) in the Treatment of Patients With Bipolar Depression

Completed· AstraZeneca logo

AstraZeneca·Phase 3·NCT00060489

Metabolism1 trial

Seroquel on Glucose Metabolism

Completed· AstraZeneca logo

AstraZeneca·Phase 4·NCT00214578·572 enrolled

Dementia1 trial

Depakote Extended Release (ER) Versus Seroquel for Agitated Behaviors in Nursing Home Care Unit Patients With Dementia

Terminated·TTuscaloosa Research & Education Advancement Corporation·Phase 3·NCT00315900·20 enrolled

Sources

References

[1]
ClinicalTrials.gov — 15 trial records for Seroquel. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Seroquel compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Seroquel. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — AstraZeneca company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: AstraZeneca

Seroquel

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Pilot Study2 trials

Schizophrenia2 trials

Social Anxiety Disorder1 trial

Alcohol Dependence1 trial

Heavy Drinker1 trial

Efficacy and Safety1 trial

Major Depressive Disorder1 trial

Bipolar Disorder1 trial

Post-Traumatic Stress Disorder1 trial

Psychosis1 trial

Safety and Efficacy1 trial

Metabolism1 trial

Dementia1 trial

References

Drug Info

Quick Facts

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