Modrastane

(Trilostane)

Phase 2Small molecule

BBioenvision

Modrastane is one of 56 small molecule programs targeting Abortion. It is currently in Phase 2.

Indications

Total Trials

Active Trials

Competitors

FDA Application

NDA/BLA/ANDA regulatory filings

Pipeline

Status by Indication[3][1]

Indication

AbortionActive, not recruiting

Prostate CancerActive, not recruiting

AbortionPhase 2

Active, not recruiting

Prostate CancerPhase 2

Active, not recruiting

Competition

Competitive Landscape

1399 competitors in Prostate Cancer

#DrugCompanyPhaseTrials

Novantrone

Pfizer

Preclinical

5 2

Modrastane

BBioenvision

Phase 2

1 3

Mekinist

Novartis

Preclinical

3 4

Trexall

Alnylam Pharmaceuticals

Preclinical

—5

Viagra

VViatris Specialty LLC

Preclinical

1 6

Ranexa

MMenarini International Operations Luxembourg SA

Preclinical

1 7

Prednisone/prednisolone

Roche

Preclinical

3 8

Triptorelin Pamoate

Ipsen

Preclinical

2 9

Ifex

BBaxter Healthcare Corporation

Preclinical

—10

Xylocaine

CCitius Pharmaceuticals, Inc.

Preclinical

—

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Abortion1 trial

Randomized Study of Letrozole and Trilostane for Medical Abortion

Terminated·KKristina Gemzell Danielsson·Phase 2·NCT01615211·36 enrolled

Prostate Cancer1 trial

Trilostane for Androgen-Independent Prostate Cancer

Completed· Sanofi logo

Sanofi·Phase 2·NCT00181597·24 enrolled

Regulatory

FDA Approval Timeline[4]

Dec 31, 1984

MODRASTANE

NDA NDA018719

Sources

References

[1]
ClinicalTrials.gov — 2 trial records for Trilostane. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Trilostane compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Trilostane. EMBL-EBI & Wellcome Sanger Institute.
[4]
OpenFDA — FDA approval records (NDA NDA018719). U.S. Food & Drug Administration.
[5]
SEC EDGAR — Bioenvision company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 2[1]
Company: BBioenvision

Modrastane

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Abortion1 trial

Prostate Cancer1 trial

FDA Approval Timeline[4]

References

Drug Info

Quick Facts

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