Uridine

ApprovedSmall molecule

UUniversity of Utah

Uridine is one of 45 small molecule programs targeting Suicidal Ideation. It is currently in Approved.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Suicidal IdeationActive, not recruiting

Cystic FibrosisActive, not recruiting

Suicidal IdeationApproved

Active, not recruiting

Cystic FibrosisPreclinical

Active, not recruiting

Competition

Competitive Landscape

386 competitors in Cystic Fibrosis

#DrugCompanyPhaseTrials

Uridine

UUniversity of Utah

Approved

1 2

Onglyza

AstraZeneca

Preclinical

2 3

Calciferol

Alnylam Pharmaceuticals

Preclinical

1 4

Vibramycin

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Preclinical

3 5

Actimmune

HHorizon Therapeutics Ireland DAC

Preclinical

2 6

Aztreonam Lysine

Gilead

Preclinical

5 7

Advil

KKenvue Brands

Preclinical

1 8

Tums

Otsuka

Preclinical

1 9

Feosol

AAuerbach Hematology Oncology Associates P C

Preclinical

1 10

Capromorelin

UUniversity of Aarhus

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Suicidal Ideation1 trial

Clinical and Imaging Trial of Uridine for Veterans With Suicidal Ideation

Completed·VVA Office of Research and Development·Phase 4·NCT03265964·75 enrolled

Randomized Controlled Trial1 trial

Uridine Adolescent Bipolar Depression Randomized Controlled Trial

Completed·UUniversity of Utah·N/A·NCT01805440·62 enrolled

Bipolar Depression1 trial

Oral Uridine for Treatment of Bipolar Depression in Adolescents

Completed·UUniversity of Utah·Phase 2·NCT00841269·42 enrolled

Cystic Fibrosis1 trial

Study of Uridine Triphosphate (UTP) as an Aerosol Spray for Cystic Fibrosis

Completed·FFDA Office of Orphan Products Development·N/A·NCT00004705

Phase II1 trial

Phase II Study of Ribose, Uridine, and Thymidine for a Complex Syndrome Involving Excessive 5'-Nucleotidase Activity

Completed·NNational Center for Research Resources (NCRR)·Phase 2·NCT00004658

3 more indications

Depression1 trial

Phase II Study to Assess RG2417 in the Treatment of Bipolar I Depression

Completed·RRepligen Corporation·Phase 2·NCT00322764·80 enrolled

CLE1 trial

Immunologic Effects of Supplemental Monosaccharide and Nucleoside Derivatives in Patients With Inherited Disorders of Glycosylation

Terminated·NNational Institute of Allergy and Infectious Diseases (NIAID)·Phase 1·NCT02511041·2 enrolled

Unspecified1 trial

Effect of Uridine on GABA and High Energy Phosphate Levels in Healthy Volunteers

Completed·MMclean Hospital·Phase 1·NCT01261260·33 enrolled

Sources

References

[1]
ClinicalTrials.gov — 8 trial records for Uridine. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Uridine compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Uridine. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — University of Utah company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Approved[1]
Company: UUniversity of Utah

Uridine

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Suicidal Ideation1 trial

Randomized Controlled Trial1 trial

Bipolar Depression1 trial

Cystic Fibrosis1 trial

Phase II1 trial

Depression1 trial

CLE1 trial

Unspecified1 trial

References

Drug Info

Quick Facts

Related News