vancomycin hydrochloride

Phase 3Small molecule

WWake Forest University Health Sciences

vancomycin hydrochloride is one of 10 small molecule programs targeting Dental Caries. It is currently in Phase 3.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Dental CariesActive, not recruiting

Infection ProRecruiting

Dental CariesPreclinical

Active, not recruiting

Infection ProPhase 3

Recruiting

Competition

Competitive Landscape

8 competitors in Dental Caries

#DrugCompanyPhaseTrials

Peridex

DDexcel Pharma Technologies Ltd.

Approved

—2

Betadine

BBecton, Dickinson and Company

Mycostatin

Zocor

vancomycin hydrochloride

WWake Forest University Health Sciences

Phase 3

1 6

KH001

HHysensBio Co., Ltd

Phase 2

1 7

Chlorhexidine Digluconate

GSK

Preclinical

1 8

Nano Silver Fluoride

OOctober University for Modern Sciences and Arts

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q1 2028

Phase 3Recruiting

Fracture

NCT05766670

Q3 2028

PreclinicalRecruiting

Ulcerative Colitis (UC)

NCT07913347

Q4 2028

Phase 3Recruiting

Infection Pro

NCT06126614

Clinical

Trials by Indication[1]

Cardiac Surgery1 trial

Topical Vancomycin Over Sternal Edge in Cardiac Surgery

Completed·NNational Cheng-Kung University Hospital·Phase 4·NCT04500275·360 enrolled

Prophylaxis1 trial

Intrawound Vancomycin Prophylaxis for Neural Stimulator

Unknown status·UUniversity of British Columbia·Phase 2/3·NCT03221023·900 enrolled

Infection Pro1 trial

Infection Prophylaxis in Total Joint Replacement

Recruiting·HHamilton Health Sciences Corporation·Phase 3·NCT06126614·21,006 enrolled

Dental Caries1 trial

The Use of Antimicrobial Agents in the Inhibition of Mutans Streptococci in Children With Dental Caries

Completed·UUniversidade Federal do Ceara·N/A·NCT00612469·69 enrolled

Ulcerative Colitis (UC)1 trial

Phase 1b/2a Study of MGT-006 in Patients With Ulcerative Colitis: A Dose and Preparation Regimen Selection Trial to Assess Safety and Microbiome Engraftment (ROOT Study)

Recruiting·MMetagen Therapeutics, Inc.·Preclinical·NCT07913347·54 enrolled

1 more indication

Fracture1 trial

Intramedullary Calcium Sulfate Antibiotic Depot for Prevention of Open Fracture Related Infection: A Randomized Clinical Trial

Recruiting·WWake Forest University Health Sciences·Phase 3·NCT05766670·242 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for vancomycin hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — vancomycin hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for vancomycin hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Wake Forest University Health Sciences company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Phase 3[1]
Company: WWake Forest University Health Sciences

vancomycin hydrochloride

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q1 2028

Q3 2028

Q4 2028

Trials by Indication[1]

Cardiac Surgery1 trial

Prophylaxis1 trial

Infection Pro1 trial

Dental Caries1 trial

Ulcerative Colitis (UC)1 trial

Fracture1 trial

References

Drug Info

Quick Facts

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