Amitriptyline hydrochloride

PreclinicalSmall molecule

NNational Institute of Allergy and Infectious Diseases (NIAID)

Amitriptyline hydrochloride is one of 60 small molecule programs targeting Peripheral Neuropathy. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Peripheral NeuropathyActive, not recruiting

FibromyalgiaActive, not recruiting

Peripheral NeuropathyPreclinical

Active, not recruiting

FibromyalgiaPreclinical

Active, not recruiting

Competition

Competitive Landscape

42 competitors in Fibromyalgia

#DrugCompanyPhaseTrials

Lyrica

PPfizer's Upjohn has merged with Mylan to form Viatris Inc.

Approved

37 2

Savella

AbbVie

Approved

15 3

Cymbalta

Jazz Pharmaceuticals

Approved

14 4

Elavil

AstraZeneca

Approved

4 5

Emgality

Eli Lilly

Approved

1 6

Keppra

UCB

Approved

1 7

Revia

Teva

Approved

—8

Seroquel

EEngelhard Arzneimittel GmbH & Co.KG

Approved

4 9

Xylocaine

MMEDRx USA, Inc.

Approved

4 10

Ultram

WWim Janssens

Approved

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Efficacy1 trial

EASE (Efficacy of ATX01 Study in Erythromelalgia)

Completed·AAlgoTherapeutix·Phase 2·NCT05917912·14 enrolled

Terminated·GGil Yosipovitch·Phase 2·NCT03096444·13 enrolled

Irritable Bowel Syndrome1 trial

To Compare the Efficacy of Drugs in Combination for Treating Irritable Bowel Syndrome Associated With Diarrhea

Completed·—·Phase 4·NCT05867550·162 enrolled

1 more indication

Peripheral Neuropathy1 trial

The Efficacy of a Standardized Acupuncture Regimen and Amitriptyline Compared With Placebo as a Treatment for Pain Caused by Peripheral Neuropathy in HIV-Infected Patients

Completed·NNational Institute of Allergy and Infectious Diseases (NIAID)·N/A·NCT00000817·260 enrolled

Sources

References

[1]
ClinicalTrials.gov — 6 trial records for Amitriptyline hydrochloride. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Amitriptyline hydrochloride compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Amitriptyline hydrochloride. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Institute of Allergy and Infectious Diseases (NIAID) company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: NNational Institute of Allergy and Infectious Diseases (NIAID)

Amitriptyline hydrochloride

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Efficacy1 trial

Fibromyalgia1 trial

HIV infection1 trial

Lidocaine1 trial

Irritable Bowel Syndrome1 trial

Peripheral Neuropathy1 trial

References

Drug Info

Quick Facts

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