Bupivacaine + Magnesium

PreclinicalSmall molecule

NNational Cancer Institute, Egypt

Bupivacaine + Magnesium is one of 2 small molecule programs targeting Mastectomy. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

AnalgesiaRecruiting

AnalgesiaPreclinical

Recruiting

Competition

Competitive Landscape

5 competitors in Analgesia

#DrugCompanyPhaseTrials

Marcaine

IInnocoll

Preclinical

5 2

Bupivacaine + Magnesium

NNational Cancer Institute, Egypt

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Timeline

Expected Milestones

Q4 2026

PreclinicalRecruiting

Analgesia

NCT05851768

Clinical

Trials by Indication[1]

Mastectomy3 trials

Serratus Anterior Plane Block Versus Erector Spinae Plane Block With Dexmedetomidine Added to Bupivacaine for Ultrasound-Guided Pain Management After Mastectomy

Completed·KKafrelsheikh University·N/A·NCT06737458·40 enrolled

Dexmedetomedine and Ketamine in Erector Spinae Block for Postoperative Analgesia Following Mastectomy.

Completed·NNational Cancer Institute, Egypt·Phase 2/3·NCT05727098·75 enrolled

Dexmedetomidine in Serratus Plane Block for Mastectomy

Completed·AAlaa Mazy·N/A·NCT03498092·150 enrolled

Suprascapular Nerve Block1 trial

Postoperative Analgesia of Magnesium Sulfate in Suprascapular Nerve Block Following Shoulder Arthroscopy

Unknown status·MMansoura University·N/A·NCT03602469·60 enrolled

Laparoscopic Cholecystectomy1 trial

Dexmedetomidine in Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy

Completed·IImam Abdulrahman Bin Faisal University·Phase 1/2·NCT02031510·195 enrolled

Caesarean Section1 trial

Intrathecal Bupivacaine-fentanyl and Bupivacaine-dexmedetomidine for Elective Low Segment Caesarean Section

Completed·—·N/A·NCT04095013·60 enrolled

Postoperative Pain Relief1 trial

Presternal Magnesium With Bupivacain Versus Bupivacain Only for Postoperative Pain Relief in Open Heart Surgery

Completed·—·N/A·NCT03230227·40 enrolled

2 more indications

Dexamethasone1 trial

Addition of MgSO4 or Dexamethasone to Bupivacaine on the Prolongation of Ultrasound-guided Quadratus Lumboram Block

Completed·—·N/A·NCT05397236·66 enrolled

Analgesia1 trial

Analgesic Efficacy of Adding Dexmedetomidine VS Magnesium Sulphate as Adjuvants With Bupivacaine in Ultrasound-guided Erector Spinae Plane Block for Post Thoracotomy Pain

Recruiting·NNational Cancer Institute, Egypt·Preclinical·NCT05851768·60 enrolled

Sources

References

[1]
ClinicalTrials.gov — 9 trial records for Bupivacaine + Magnesium. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Bupivacaine + Magnesium compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Bupivacaine + Magnesium. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — National Cancer Institute, Egypt company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Small molecule[2]
Highest Phase: Preclinical[1]
Company: NNational Cancer Institute, Egypt

Bupivacaine + Magnesium

Status by Indication[3][1]

Competitive Landscape

Expected Milestones

Q4 2026

Trials by Indication[1]

Mastectomy3 trials

Suprascapular Nerve Block1 trial

Laparoscopic Cholecystectomy1 trial

Caesarean Section1 trial

Postoperative Pain Relief1 trial

Dexamethasone1 trial

Analgesia1 trial

References

Drug Info

Quick Facts

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