Calcitonin Gene-Related Peptide

PreclinicalPeptide

Calcitonin Gene-Related Peptide is one of 55 small molecule programs targeting Migraine Without Aura. It is currently in Preclinical.

Indications

Total Trials

Active Trials

Competitors

Pipeline

Status by Indication[3][1]

Indication

Migraine Without AuraActive, not recruiting

MigraineActive, not recruiting

Cluster HeadacheActive, not recruiting

Migraine Without AuraPreclinical

Active, not recruiting

MigrainePreclinical

Active, not recruiting

Cluster HeadachePreclinical

Active, not recruiting

Competition

Competitive Landscape

357 competitors in Migraine

#DrugCompanyPhaseTrials

Aimovig

Amgen

Preclinical

33 2

Emgality

Eli Lilly

Preclinical

19 3

Vyepti

Lundbeck

Preclinical

12 4

Savella

AbbVie

Preclinical

2 5

Bayer Aspirin

Bayer

Preclinical

2 6

Cymbalta

Alnylam Pharmaceuticals

Preclinical

1 7

Viagra

VViatris Specialty LLC

Preclinical

2 8

Pristiq

PPrism Pharmaceuticals

Preclinical

1 9

Non-Steroidal Anti-Inflammatory Drugs (NSAID)

Roche

Preclinical

1 10

Bupivacaine Only

Pacira Pharmaceuticals, Inc

Preclinical

Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.

Clinical

Trials by Indication[1]

Headache3 trials

Clinical Characteristics and Pathophysiology of Post-Traumatic Headache

Completed·DDanish Headache Center·N/A·NCT03791515·200 enrolled

The Effect of Anti-calcitonin Gene-related Peptide (CGRP) Receptor Antibodies on the Headache Inducing Properties of CGRP and Cilostazol in Migraine Patients

Unknown status·DDanish Headache Center·N/A·NCT04452929·72 enrolled

The Effect of Sumatriptan and Placebo on CGRP Induced Headache

Completed·DDanish Headache Center·N/A·NCT03542357·30 enrolled

Migraine2 trials

Hypersensitivity to CGRP as a Predictive Biomarker of Migraine Prevention With Erenumab

Unknown status·DDanish Headache Center·Phase 4·NCT04592952·400 enrolled

CGRP-induced Migraine Attacks in Patients Who Have Tried Anti-CGRP Monoclonal Antibody Treatment

Unknown status·DDanish Headache Center·N/A·NCT03481400·40 enrolled

Cluster headache1 trial

CGRP's Cluster Headache Inducing Abilities in Cluster Headache Patients

Completed·DDanish Headache Center·N/A·NCT02466334·37 enrolled

Migraine Without Aura1 trial

Pharmacologically Triggered Migraine Without Aura and Neuroimaging

Unknown status·DDanish Headache Center·N/A·NCT03143465·36 enrolled

Sources

References

[1]
ClinicalTrials.gov — 7 trial records for Calcitonin Gene-Related Peptide. U.S. National Library of Medicine, National Institutes of Health.
[2]
ChEMBL — Calcitonin Gene-Related Peptide compound record. European Bioinformatics Institute (EMBL-EBI).
[3]
Open Targets Platform — Drug–disease associations for Calcitonin Gene-Related Peptide. EMBL-EBI & Wellcome Sanger Institute.
[4]
SEC EDGAR — Danish Headache Center company filings. U.S. Securities and Exchange Commission.

Details

Drug Info

Quick Facts

Modality: Peptide[2]
Highest Phase: Preclinical[1]
Company: DDanish Headache Center

Calcitonin Gene-Related Peptide

Status by Indication[3][1]

Competitive Landscape

Trials by Indication[1]

Headache3 trials

Migraine2 trials

Cluster headache1 trial

Migraine Without Aura1 trial

References

Drug Info

Quick Facts

Related News