VivoSeq
Other

Headache

176

Pipeline Programs

25

Active Trials

48

Companies Involved

Headache is a highly competitive landscape with 176 programs across 48 companies. The most active players are COMPASS Pathways, Eli Lilly, Solvay Pharmaceuticals. 57 therapies are approved with 24 more in late-stage development.

Pipeline Metrics

Competitive Density

78/100

Pipeline Velocity

27/100

Mech. Concentration

11/100

Completion Rate

76/100

Attrition Rate

19/100

Competitive Landscape

Bubble size = clinical trials

Approved
Phase 3
Phase 2
Phase 1
Preclinical

Programs by Phase

Modality Breakdown

96%

Small molecule

203 of 212 classified programs — the dominant modality here.

4%ALL OTHERSPeptide52%Monoclonal antibody42%

Small molecule leads; the ring shows all 212 classified programs, each share of the total. Modality classified for 100% of 222 pipeline programs.

Trial Status

264

clinical trials

Completed156 · 59%
Unknown status33 · 13%
Terminated33 · 13%
Withdrawn17 · 6%
Recruiting15 · 6%
Not yet recruiting7 · 3%
Other3 · 1%

Trial Activity

264 trials

Responding With Evidence and Access for Childhood Headaches
Recruiting··N/A·NCT05889624·400 enrolled
China HeadAche DIsorders RegiStry
Recruiting·BBeijing Tiantan Hospital·N/A·NCT05334927·10,000 enrolled
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Data sources: ClinicalTrials.gov (NIH) · OpenFDA (FDA) · ChEMBL (EMBL-EBI) · Open Targets (EBI/Sanger) · MedlinePlus (NIH) · PubMed (NIH) · SEC EDGAR (SEC)