Cocaine HCl
(Cocaine)ApprovedSmall molecule
Cocaine is a local anesthetic used medically to numb tissues during certain surgical procedures, particularly in nasal and ear surgery. It also constricts blood vessels, which helps reduce bleeding during these procedures.[2] Cocaine HCl is currently approved and in use across 4 indications[4].[1]
Cocaine HCl is one of 112 small molecule programs targeting Cocaine Abuse. It is currently in Approved.
4
Indications
28
Total Trials
0
Active Trials
111
Competitors
2
FDA Applications
NDA/BLA/ANDA regulatory filings
12
Patents
Pipeline
Status by Indication[4][1]
Indication
Competition
Competitive Landscape
101 competitors in Cocaine Dependence
#DrugCompanyPhaseTrials
1Cocaine HCl
OOmnivium
Approved
Permax
VValeant Pharmaceuticals
Phase 3
Bupropion XL
GSKPhase 3
Celexa
AbbViePhase 2
Buspar
Bristol-Myers SquibbPhase 2
Dostinex
PfizerPhase 2
Sabril
LundbeckPhase 2
Ritalin
NovartisPhase 2
Tegretol
NovartisPhase 2
Zofran
NovartisPhase 2
Ranked by pipeline maturity and clinical activity. Current drug highlighted in teal.
Clinical
Trials by Indication[1]
AIN8 trials
Interaction3 trials
Drug3 trials
Cocaine Abuse3 trials
8 more indications
Cocaine Dependence2 trials
Complementary Combination Therapy for Cocaine Dependence
Completed·—·Phase 1·NCT02538744·45 enrolled
Anesthesia1 trial
Cocaine Use Disorder1 trial
Regulatory
FDA Approval Timeline[5]
Dec 14, 2017
GOPRELTO
NDA NDA209963
Jan 10, 2020
NUMBRINO
NDA NDA209575
Sources
References
- [1]
- [2]MedlinePlus Drug Information — Cocaine HCl drug information. U.S. National Library of Medicine, National Institutes of Health.
- [3]
- [4]Open Targets Platform — Drug–disease associations for Cocaine. EMBL-EBI & Wellcome Sanger Institute.
- [5]
- [6]
- [7]